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4 Oct, 5 tweets, 1 min read
For those interested in facts, there are two more fraudulent ivermectin trials with news dropping this week, at least two more with very high probability of fraud soon to come
It's also worth noting that when I talk about fraud, I'm only considering clinical and observational trials. Most of the ecological trials are so woeful that it doesn't really matter if anyone faked them, and I don't really assess basic science
Anyway, if you want to know exactly how many studies are flawed, we'll hopefully have it all up this week. Takes time to assemble this stuff working unpaid in our free time!
HAHAHAHAHA

"There may be slightly less fraud in the ivermectin space than the absolute worst-case scenario proposed in a recent BMJ editorial" is not the argument you think it is, Alex 😂😂😂

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More from @GidMK

Health Nerd Profile picture
4 Oct
Lots of people have been asking me to take a look at this observational ivermectin trial from Argentina, and I thought it'd be a nice change from all the fraud so here's a bit of a thread 1/n
2/n The trial is here, and it is a fairly simple epidemiological trial comparing people who were given ivermectin with those who weren't on ICU admission/death using large-scale registries in Argentina
zenodo.org/record/5525362…
3/n I've done a brief check for fraud, and the study looks fine. Honestly, I have no real issues with this paper as is, it's just not very useful as evidence for ivermectin

Let's think about why that is
Read 14 tweets
Health Nerd Profile picture
2 Oct
Our big new study on the infection fatality rate of COVID-19 in developing countries is out

The news is pretty grim 🧵

medrxiv.org/content/10.110…
Throughout the pandemic, there has been an apparent contradiction - low-income places appear to have lower death rates from COVID-19 than higher-income areas

This makes no sense on the face of it
So, we looked at the infection fatality rate (IFR) of COVID-19 in every place that we could find, using antibodies to estimate the number of infections in each area and the number of registered deaths as our numerator
Read 15 tweets
Health Nerd Profile picture
25 Sep
Interesting paper. Seems to make it extremely unlikely that SARS-CoV-2 was created in a lab
It is amazing how many people mischaracterize "extremely likely" as "the only possible answer"

No, this does not mean that a lab leak is totally impossible
That being said, the appearance of very closely-related coronaviruses in non-lab settings obviously makes a natural origin quite likely, especially as there are no more closely related viruses in labs 🤷‍♂️
Read 4 tweets
Health Nerd Profile picture
23 Sep
I cannot believe the question was asked, and the response is even more absurd

No, the pandemic is not a "social construct" what utter garbage
Even the explanation of why the pandemic is "socially constructed" is total nonsense. That we may have had a different response without technology does not mean that what we are doing now is "constructed" in a philosophical sense
I mean, if the pandemic had happened 3 decades ago it's almost certain that the death toll would be FAR higher, so we might have actually had a MORE intensive regulatory response
Read 5 tweets
Health Nerd Profile picture
22 Sep
The ivermectin literature is full of fraud

What can we do about it?

Our new paper in @NatureMedicine argues that we need a systematic change to counter this issue

nature.com/articles/s4159…
The basic issue is that science works on trust. We assume that no one would ever fake a study, because it's ethically and morally indefensible, and work with that

Which makes it very easy for people to fake studies
However, people generally aren't very good at faking things. There are dozens of very simple checks you can run on data to see if it's real

Problem is, you need the data to do that
Read 5 tweets
Health Nerd Profile picture
21 Sep
It is demonstrably false to claim that intubation has led to more deaths during the COVID-19 pandemic, but this has not stopped Professor Ioannidis making the claim repeatedly

sciencebasedmedicine.org/intubations/
I also find the persistent myth that Prof Ioannidis promotes that death certification has lead to more Covid-19 deaths rather odd. I cannot find any basis for this in the literature he cites
For example, in this recent paper he makes the same claim and cites two papers. One is simply a guide to death certification, and not really an assessment of errors
Read 7 tweets

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