Thread by @BenjaCurrents

Nature 2005: "Caution raised over SARS vaccine"
"Jab against one strain might worsen infection with others."
nature.com/articles/news0…

"A cautionary note has been sounded for those developing vaccines against severe acute respiratory syndrome (SARS). Some vaccines could prove useless against certain strains, or even worsen the infection, a preliminary study suggests."

"The results show that the virus changes over time, so that a strain that crops up in one outbreak might be quite different from that in a later outbreak. "This virus is not standing still and we need to take this into account," Nabel says."

"This wouldn´t be the first case where exposure to one strain of a virus can worsen infection with another. In the mosquito-borne disease dengue fever, e.g., people who have been infected with one strain are likely to suffer a worse infection if they pick up a second strain."

"Figuring this out might thwart potential problems in vaccines"

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