Singapore is surging. We will have multiple “Singapores” here in the US. Their surge is higher than any they’ve had. 83% fully vax’d @ the time of this graph.

Does this look like u can’t surge if u have a significant amount of vax in your country or state? US is 57% fully vax’d. Image
What say you? But is it impacting their healthcare services? YES. “Singapore ministers told a media briefing on Friday that the jump in COVID-19 cases in the island of 5.7 million people had put ‘tremendous’ pressure on its healthcare system.”
reuters.com/world/asia-pac…
But has it required them to increase mitigations again? YES. Long lines started forming at the emergency departments @ several hospitals. With cases doubling every 8-10 days, the government limited social gatherings to 2 people & told people once again they should work from home.
“If the health care system gets overwhelmed, that’s when we know from experience everywhere that doctors are unable to cope and you have death rates start to go up,” Mr. Wong said. “So we are trying very hard to avoid that.” reuters.com/world/asia-pac…
“The vaccines have worked to keep most of the population out of the hospital, w/ 98.4 percent of cases presenting mild or no symptoms. But the shots cannot protect against infection [& may not block Long Covid enough], especially when up against the Delta variant, Mr. Wong said.
And what does this mean for the US or many other countries in the world that are fairly vaccinated? We repeatedly hear estimates that only 5% of Americans have been infected with Delta. Many Americans are more than 4-6 months out from their last infection or their last vax dose.
And the above assessment does not even include the fair probability of a new coronavirus variant, especially one that pierces prior immunity. Even 1 that already exists, Mu, is holding its own against Delta in Columbia. It may be waiting in the wings post Delta. H/T @DrEricDing Image
Dr. Ugur Sahin, Founder of BioNTech
@VirusesImmunity
Virus is “just beginning” to escape immune responses. Other molecules may be involved in uptake of the virus & entry of virus. The spike should not be our only focus. Prepare for unexpected evolution.

@VirusesImmunity You mentioned in the past that you’ve seen CoV2 variants that don’t need the ACE receptor to enter.
@fitterhappierAJ @DrEricDing @DrWilliamKu @emilygraymd_mph @dgurdasani1 @RadCentrism @BidoliNicola @segal_eran @PeterHotez @trvrb @ScottGottliebMD @ahandvanish
The AY.23 (Delta sub-lineage) rose rapidly in Singapore during July and has almost totally displaced B.1.617.2 ("ancestral" Delta). Variants didn’t stop when we decided that ancestral Delta was “probably the last significant surge”. Let’s stop making this mistake. Image
Still tremendous pressure on healthcare systems & potential for significant Long Covid which can be as impactful as deaths on a country. We have the “famine of corms effect” going on all over the world w/ multiple sectors & countries having trouble hiring despite many open jobs.
This is a coronavirus pandemic that can last decades to generations. It’s not a flu pandemic that lasts 3 waves. We only slow this down as fast as we can race against this significant foe. VAX, BOOST, MASK, UPDATE VAX, & hope for ANTIVIRAL COCKTAIL with limited side effects.
“…a coronavirus epidemic swept East Asia some 20,000 years ago & was devastating enough to leave an evolutionary imprint (this means a lot of people died or could not reproduce) on the DNA of people alive today.” That’s a coronavirus epidemic that lasted decades or generations.
LC can be as impactful as death:
“…post-viral syndrome has been blamed for triggering the worst famine in a century—the so-called “famine of corms”—after debilitating lethargy prevented flu survivors from planting when the rains came at the end of 1918.” apple.news/AUoorvbszQkyuX…
As requested:
What is the level of hospitalizations in a country 83% fully vax’d (Pfizer and Moderna) and just starting to deal with AY.23? Image

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More from @maryaalexand1

29 Jul
1. Delta behavior indoors & outdoors: they saw fleeting proximity transmission in the Bondi Junction outbreak. Only needed 5-10 seconds proximity or 1-3 inhalations if briefly within 2 ft of someone else.
These kinds of transmission occurred when just “brushing past” someone & was well documented for indoor cases by genomic testing and CCTV. They also had a case of a woman sitting outdoors at a cafe who was infected by a man who visited the cafe when she was not inside.
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