On the EcoHealth+WIV report, I told @theintercept
"one of their chimeric SARS-like viruses caused more severe disease in a humanized animal model than the original virus. After seeing that.. why did they do similar work using the MERS human pathogen?”
theintercept.com/2021/10/21/vir…
@theintercept In August 2021, the EcoHealth Alliance submits the 2019 report to the NIH, 2 years late, detailing the chimeric MERS-CoV work.

In September 2021, the EcoHealth Alliance told @theintercept “The MERS work proposed in the grant is suggested as an alternative and was not undertaken”
Has this middleman organization completely broken down? What is happening in there?
In April 2018, the NIH received the EcoHealth Alliance report showing chimeric viruses with >10x enhanced viral loads in the lung of humanized mice. This report also stated that they were moving on to do similar work with MERS-CoV.

Was there any intervention to stop this?
Who in their right mind unintentionally creates chimeric SARS-like virus with enhanced pathogenicity in humanized mice and intentionally decides to do more of the same work with human pathogen MERS, in a city of 11 million people with international flights to major tourist areas?
Tell us what BSL the live chimeric MERS-CoV work was performed at @EcoHealthNYC

Was it also BSL2 (low biosafety level, cannot protect against airborne pathogens) just like where the chimeric SARS-like virus work had been performed?
@EcoHealthNYC No scientist/student should be put in a position where a single moment of carelessness can lead to millions of deaths.

There is no one, regardless of skill, who should be entrusted to take on such a burden.
At this rate the 3rd CoV pandemic out of China might be a MERS-like virus.

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More from @Ayjchan

21 Oct
From August 2020:

“At the time that [NIH to EcoHealth] grant was revoked, conspiracy theories suggested the virus may have emerged from the Wuhan lab. As NPR has reported, many scientists who study viruses called that scenario nearly impossible.” npr.org/sections/goats…
Bringing this up because “EcoHealth Alliance is one of 11 institutions and research teams receiving grants from NIH, announced [August 2020], to establish the Centers for Research in Emerging Infectious Diseases.”

EcoHealth is still being funded by NIH to do more virus hunting.
I’m not saying these programs should be defunded but that they should at least be subject to a higher level of accountability and transparent reporting (open access to emerging data) to prevent against worst case scenarios.
Read 4 tweets
20 Oct
The type of experiments conducted at the WIV could have led to the emergence of SARS2.

In this explainer, NIAID is saying that the -exact- viruses used in the -exact- experiments described in the literature and recently FOIA'ed docs did not create SARS2.
niaid.nih.gov/diseases-condi…
What do we know?

1. WIV's public data describe mostly viruses sampled up to 2016. 3 yrs before 2019.

2. There's a missing WIV pathogen sample database of 22,000+ entries.

3. In early 2018, EcoHealth/WIV had a roadmap to insert novel cleavage sites into novel SARS-like viruses.
What would help is for the EcoHealth Alliance and other WIV collaborators to publish all communications and documents (including unfunded proposals) involving the WIV.

That would go a very long way in helping us to understand what SARS-like virus work was happening in Wuhan.
Read 4 tweets
19 Oct
Is it too much to ask for @who to please not appoint SAGO members who have called the lab leak hypothesis a conspiracy theory?

Is this very challenging for the WHO? To pick 26 non-controversial experts to track the #OriginOfCovid?
You’re telling me that out of 700 SAGO applicants, these 26 names were the least conflicted / controversial?

Did the entire EcoHealth Alliance & gain-of-function friends network apply or something?
There should be 2 qualifiers for SAGO members:

1. What are the problems they have identified in the first China-WHO joint study and its report?

2. What are their comments on the DEFUSE proposal and NIH report showing gain-of-function SARSrCoV work by WIV/EcoHealth?
Read 4 tweets
19 Oct
Even if you’re convinced that SARS2 emerged completely naturally, it is in your interest that a credible and balanced investigative #OriginOfCovid team is established.

If an imbalanced team is set up, it’s not going to convince people on the other side.
cbc.ca/news/health/wh…
Where I’m sitting, I see people tweeting that it’s obvious the virus came from a lab / nature. There are people on each side that are equally convinced that “everyone knows” where this virus came from.

We need a balanced #OriginOfCovid investigation that both sides can trust.
I told @markgollom @CBCNews “Most of the international experts convened on the highly criticized initial joint study with China are back on SAGO. It will now be difficult to convince people that the new SAGO will be much different from the original joint study group.”
Read 6 tweets
19 Oct
“Daszak.. at the center of yet another maelstrom.. a leaked grant application.. controversial experiments that could alter bat coronaviruses in a way that may have given them a “gain of function,” potentially creating human pathogens with pandemic powers.” science.org/content/articl…
Daszak who had been placed in the @WHO & @TheLancet #OriginOfCovid teams did not tell them that he and WIV had engineered chimeric SARS-like viruses with 10,000x higher viral loads in humanized mice, and by 2018 had seen novel cleavage sites they planned to insert into SARSrCoVs.
We need to see all of the communications at EcoHealth and UNC relating to the discussion of novel cleavage site detection and/or insertion into virus in the lab.
Read 4 tweets
18 Oct
"To chair the task force Sachs initially chose zoologist Peter Daszak, one of the world’s most experienced researchers of bat coronaviruses."

Enough said.
science.org/content/articl…
"The other 11 people on the task force refused to remove Daszak from their ranks, but agreed to make Keusch their chair instead."

Yep. Disband them.
"On 10 September, [Sachs] learned details of an NIH grant to EcoHealth.. following FOIA requests from @theintercept. Keusch and three other task force members are listed as co-investigators. “None of them reported this involvement with the EcoHealth Alliance.."
Read 9 tweets

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