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Billy Bostickson 🏴👁&👁 🆓 Profile picture
@BillyBostickson
Oct 27, 2021 • 20 tweets • 18 min read • Read on X
Scrolly
The Good, Bad & the Ugly with @THAILANDMEDICA1
1. thailandmedical.news/news/breaking-…

Paper: COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes

insight.jci.org/articles/view/…
2. Does your Brain hurt?

thailandmedical.news/news/saudi-ara…

Paper: Brain MRI in SARS-CoV-2 pneumonia patients with newly developed neurological manifestations suggestive of brain involvement

nature.com/articles/s4159…
3. Yes, my brain hurts, doctor!

thailandmedical.news/news/breaking-…

Paper:

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

nature.com/articles/s4159…
4. Cognitive Decline and Brain Fog

thailandmedical.news/news/icahn-stu…

Paper: Assessment of Cognitive Function in Patients After COVID-19 Infection

jamanetwork.com/journals/jaman…
4. You Microclot! You Inflammatory Molecule!

thailandmedical.news/news/breaking-…

Paper: Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin

cardiab.biomedcentral.com/articles/10.11…
5. Deviled Kidneys?

thailandmedical.news/news/more-grea…

Paper: Kidney Outcomes in Long COVID

jasn.asnjournals.org/content/early/…

jasn.asnjournals.org/content/jnephr…
6. We are all effed?

thailandmedical.news/news/breaking-…

Paper: Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection
A Systematic Review

jamanetwork.com/journals/jaman…

n this systematic review of 57 studies comprising more than 250 000 survivors of COVID-19,
7. How dare you alter my Genes without permission!

thailandmedical.news/news/breaking-…

Paper: Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae

medrxiv.org/content/10.110…
8. New Variants and Mutations (1)

You can run but you can't hide..

thailandmedical.news/news/breaking-…

Paper: The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency

nature.com/articles/s4142…
9. New Variants and Mutations (2)

SARS-COV-2 gets a Break out of Jail Free Card

Hotspot Mutations and Immune Evasion

thailandmedical.news/news/swiss-stu…

Paper: Mutational hotspot in the SARS-CoV-2 Spike protein N-terminal domain conferring immune escape potential

biorxiv.org/content/10.110…
10. New Variants and Mutations (3)

Baton Rouge Mutants

thailandmedical.news/news/louisiana…

News: What do we know about the new Louisiana COVID-19 variant?

deseret.com/coronavirus/20…
11. New Variants and Mutations (4)

Don't go to Cape Cod

thailandmedical.news/news/harvard-a…

Paper: Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts

medrxiv.org/content/10.110…
12. Oi, Pfizer, did you just steal my N Antibodies?

thailandmedical.news/news/uk-health…

with useful list of 91 studies on natural immunity

Document (UK):

assets.publishing.service.gov.uk/government/upl…
13. Single agent monoclonal antibodies? Hilarious?

@THAILANDMEDICA1 puts the boot in again(Image 1)
thailandmedical.news/news/hilarious…
Paper: Acquisition & onward transmission of a SARS-CoV-2 E484K variant among household contacts of a bamlanivimab-treated patient
medrxiv.org/content/10.110…
14. One for @Daoyu15 Too complex for me.

Monoclonal Antibody Related

thailandmedical.news/news/breaking-…

Paper: Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis

biorxiv.org/content/10.110…
15. Role of Lipids

thailandmedical.news/news/universit…

Paper: The roles of lipids in SARS-CoV-2 viral replication and the host immune response

jlr.org/article/S0022-…
16. "Palmitoylation" 🤲🤦🤦‍♂️🤦‍♀️

thailandmedical.news/news/universit…

Paper: Inhibition of SARS-CoV-2 spike protein palmitoylation reduces virus infectivity

biorxiv.org/content/10.110…

"Palmitoylation of the 1st 5 cysteine residues of the spike c-terminal cysteine-rich domain are indispensable"
17. Finished with Bad & Ugly, now Good news
1. Manuka Honey
thailandmedical.news/news/qatar-uni…
2. Basil (Fenchol)
thailandmedical.news/news/fenchol-a…
3. Glucose Regulating Drugs
thailandmedical.news/news/penn-stat…
4. Zofran (Antiemetic)
thailandmedical.news/news/new-ameri…
5. Atovaquone (antimicrobial)
thailandmedical.news/news/danish,-c…
18. I hope this thread was not too depressing?

If it was, the solution is at hand, mushroom soup :)

thailandmedical.news/news/penn-stat…

Mushroom intake and depression

"Mushroom consumers had a lower odd of depression"

sciencedirect.com/science/articl…
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More from @BillyBostickson

Billy Bostickson 🏴👁&👁 🆓 Profile picture
Dec 19
1. Russian Biolab Claims: A Controversial Topic

Good luck using your critical thinking skills to seperate wheat from chaff so that you can decide what is propaganda & what is fact.

Of course the easy options are to dismiss everything as lies or to swallow everything as fact.
2. What I recommend

If you are interested in a balanced analysis of the Russian claims and all the detailed evidence presented by Kirillov before his assassination in Moscow, as well as relted topics, then I highly recommend you plough through those threads at your leisure.
3. Documents & Russian claims on Projects UP-4 (avian flu) Flu-Flyway (wild ducks & bird flu), P-781 (bat coronaviruses), UP-8 (CCHF, Leptospirosis Hanta viruses):

Read 15 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Dec 15
1. 'CONSPIRACY OF SILENCE"

Pentagon was told 6 times that Covid was lab leak at start of pandemic – but buried the truth, ex-intel official says.

Story now published with intriguing detail by @imogen_braddick after we informed her of John Myers Tweet

thesun.co.uk/news/32257526/… x.com/BillyBostickso…
2. John Myers said that:

he "knows with absolute certainty" that top US military chiefs were told Covid had leaked from a lab in Wuhan.

"the Joint Chiefs of Staff were briefed in October 2019 - more than five years ago - about a new virus that had leaked from a lab in China"
3. Claims

This was briefed in Oct& Nov 2019 as a lab leak.

It was in the intelligence. We briefed it. It was accepted. I briefed it numerous times about a viral outbreak and that it was from a lab.

"Over the course of late Nov & Dec, it came up 6 or 7 times in briefings.
Read 15 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Dec 12
🧵📸 We have now solved the Pangolin Riddle!

This is BIG so sit tight!

1. WIV did have Pangolins in 2019 (we now have proof)

2. WIV isolated Pangolin/HKU4/MERS like Covs with Furin Sites in 2019, just before the pandemic!
3. Important Note

If you have not done so already, please read the linked thread above before continuing, it will make much more sense if you do so.
4. GX Pangolins at WIV in 2019!

From the Horse's Mouth in 2024!

"In 2019 & 2020, 86 anal swab samples & 80 serum samples were collected from Guangxi pangolins"

"Pangolin samples were transported & stored at Wuhan Institute of Virology, CAS"

cell.com/cell/fulltext/…Image
Read 53 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Dec 11
Missing Documents from EHA & Peter Daszak

He hid all WeChat comms with WIV & Zhengli Shi from @COVIDSelect

However, EHA provided the #DOJ subpoena with tens of thousands of unredacted comms stretching back a decade.

AND where are these OIG audits:

#DHHS
@USGAO
@NIH
@USAID
1. @COVIDSelect @mitch_benzine @RepBradWenstrup

Have much more unreleased information

@COVIDSelect @mitch_benzine @RepBradWenstrup 2. DOJ Audit

1. "DOJ subpoenaed EcoHealth’s communications (inlcuding WeChat) with, at least, Dr. Shi. This subpoena included both Dr. Shi’s official WIV email address & her Hotmail"

2. “DoJ subpoena for genetic sequences, docs — almost complete”

nypost.com/2024/12/02/us-…
Read 9 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Dec 11
Pangolin Riddle!

MpCoV-GX Isolated in 2017 said YiGang Tong

BUT ZLS & Yi GangTong in 2023 said:

"MpCoV-GX was isolated in 2019"

SARS-CoV-2-Related Virus from Malayan Pangolin

pmc.ncbi.nlm.nih.gov/articles/PMC99…

Accession data says submission date is 8 FEB 2020

ncbi.nlm.nih.gov/nuccore/MT0403… x.com/BillyBostickso…
2. Double Confirmed

Yi Gang Tong confrimed again the 2017 isolation date for MpCov-GX.

He experimented with it, but did not write a paper, and they did not upload the sequence until 8th Feb 2022, just after the beginning of the SARS-COV-2 pandemic

3. Why is this significant?

Yi Gang Tong stated in a paper received on 22 Feb 2020:

"no suspected infections were found in those having close contacts with pangolins"

"Our pangolin coronavirus isolate was routinely cultured in BSL 2 FACILITIES"

Read 20 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Nov 29
Most interesting RaTG13 - SARS-COV 2 paper ever written by Chinese Scientists!

Received 17 July 2020 before Gag Orders kicked in.

Comparative Genomic Analyses Reveal Specific Mutation Pattern Between SARS-CoV-2 & RaTG13

frontiersin.org/journals/micro…

See Tweeets 32 to 35 for Why 👇 x.com/BillyBostickso…
2. Potential Effects of 5-FU

Use of 5-FU during serial passage could lead to increased mutation rates in RNA viruses which might result in variants in enhanced virulence.

However, this is not guaranteed; many mutations can be deleterious rather than beneficial.
3. Using 5-FU

5-fluorouracil can induce mutations during serial passage of RNA viruses that could lead to variants with altered virulence characteristics.

Outcome would depend on specific virus involved, the nature of induced mutations & environmental pressures during passage. Image
Read 6 tweets

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