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Billy Bostickson 🏴👁&👁 🆓 Profile picture
@BillyBostickson
Oct 27, 2021 • 20 tweets • 18 min read • Read on X
Scrolly
The Good, Bad & the Ugly with @THAILANDMEDICA1
1. thailandmedical.news/news/breaking-…

Paper: COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes

insight.jci.org/articles/view/…
2. Does your Brain hurt?

thailandmedical.news/news/saudi-ara…

Paper: Brain MRI in SARS-CoV-2 pneumonia patients with newly developed neurological manifestations suggestive of brain involvement

nature.com/articles/s4159…
3. Yes, my brain hurts, doctor!

thailandmedical.news/news/breaking-…

Paper:

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

nature.com/articles/s4159…
4. Cognitive Decline and Brain Fog

thailandmedical.news/news/icahn-stu…

Paper: Assessment of Cognitive Function in Patients After COVID-19 Infection

jamanetwork.com/journals/jaman…
4. You Microclot! You Inflammatory Molecule!

thailandmedical.news/news/breaking-…

Paper: Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin

cardiab.biomedcentral.com/articles/10.11…
5. Deviled Kidneys?

thailandmedical.news/news/more-grea…

Paper: Kidney Outcomes in Long COVID

jasn.asnjournals.org/content/early/…

jasn.asnjournals.org/content/jnephr…
6. We are all effed?

thailandmedical.news/news/breaking-…

Paper: Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection
A Systematic Review

jamanetwork.com/journals/jaman…

n this systematic review of 57 studies comprising more than 250 000 survivors of COVID-19,
7. How dare you alter my Genes without permission!

thailandmedical.news/news/breaking-…

Paper: Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae

medrxiv.org/content/10.110…
8. New Variants and Mutations (1)

You can run but you can't hide..

thailandmedical.news/news/breaking-…

Paper: The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency

nature.com/articles/s4142…
9. New Variants and Mutations (2)

SARS-COV-2 gets a Break out of Jail Free Card

Hotspot Mutations and Immune Evasion

thailandmedical.news/news/swiss-stu…

Paper: Mutational hotspot in the SARS-CoV-2 Spike protein N-terminal domain conferring immune escape potential

biorxiv.org/content/10.110…
10. New Variants and Mutations (3)

Baton Rouge Mutants

thailandmedical.news/news/louisiana…

News: What do we know about the new Louisiana COVID-19 variant?

deseret.com/coronavirus/20…
11. New Variants and Mutations (4)

Don't go to Cape Cod

thailandmedical.news/news/harvard-a…

Paper: Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts

medrxiv.org/content/10.110…
12. Oi, Pfizer, did you just steal my N Antibodies?

thailandmedical.news/news/uk-health…

with useful list of 91 studies on natural immunity

Document (UK):

assets.publishing.service.gov.uk/government/upl…
13. Single agent monoclonal antibodies? Hilarious?

@THAILANDMEDICA1 puts the boot in again(Image 1)
thailandmedical.news/news/hilarious…
Paper: Acquisition & onward transmission of a SARS-CoV-2 E484K variant among household contacts of a bamlanivimab-treated patient
medrxiv.org/content/10.110…
14. One for @Daoyu15 Too complex for me.

Monoclonal Antibody Related

thailandmedical.news/news/breaking-…

Paper: Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis

biorxiv.org/content/10.110…
15. Role of Lipids

thailandmedical.news/news/universit…

Paper: The roles of lipids in SARS-CoV-2 viral replication and the host immune response

jlr.org/article/S0022-…
16. "Palmitoylation" 🤲🤦🤦‍♂️🤦‍♀️

thailandmedical.news/news/universit…

Paper: Inhibition of SARS-CoV-2 spike protein palmitoylation reduces virus infectivity

biorxiv.org/content/10.110…

"Palmitoylation of the 1st 5 cysteine residues of the spike c-terminal cysteine-rich domain are indispensable"
17. Finished with Bad & Ugly, now Good news
1. Manuka Honey
thailandmedical.news/news/qatar-uni…
2. Basil (Fenchol)
thailandmedical.news/news/fenchol-a…
3. Glucose Regulating Drugs
thailandmedical.news/news/penn-stat…
4. Zofran (Antiemetic)
thailandmedical.news/news/new-ameri…
5. Atovaquone (antimicrobial)
thailandmedical.news/news/danish,-c…
18. I hope this thread was not too depressing?

If it was, the solution is at hand, mushroom soup :)

thailandmedical.news/news/penn-stat…

Mushroom intake and depression

"Mushroom consumers had a lower odd of depression"

sciencedirect.com/science/articl…
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More from @BillyBostickson

Billy Bostickson 🏴👁&👁 🆓 Profile picture
Nov 8
@Daoyu15 @jhas5 @Fynnderella1 Not sure what your point is ragrding hACE2 mice infection.

Have you read all the other hACE2 mouse model papers that show SC2 infection.

I have!

Here are 15 of them, please read them:

1. Animal models for SC2 and SC1 pathogenesis & transmission

pmc.ncbi.nlm.nih.gov/articles/PMC87…
@Daoyu15 @jhas5 @Fynnderella1 2. Mouse Models for SC2 Infection

pmc.ncbi.nlm.nih.gov/articles/PMC85…

3. Highly susceptible hACE2-transgenic mouse model for SC-2 research

frontiersin.org/journals/micro…

4. Inducible hACE2 transgenic mouse model recapitulates SC-2 infection & pathogenesis in vivo

pnas.org/doi/abs/10.107…
@Daoyu15 @jhas5 @Fynnderella1 5. Mouse Model of SC-2 Infection & Pathogenesis

sciencedirect.com/science/articl…

6. Mouse models of lung-specific SC-2 infection

frontiersin.org/journals/immun…

7. Comparison of transgenic & adenovirus hACE2 mouse models for SARS-CoV-2 infection

tandfonline.com/doi/full/10.10…
Read 8 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Nov 7
@Ticklicker56 @Biorealism Yes, we thoroughy researched this issue some time ago.

Difficult to prove anything, but certainly raises suspicions.
@Ticklicker56 @Biorealism Interestingly, the E protein and nsp7 of ZC45 are 100% identical to those of SARS-COV-2.

Even Holmes (Wu et al., 2020) listed ZC45 as closest in Feb 2020 until the RaTG13 full genome was published in March

nature.com/articles/s4158…
@Ticklicker56 @Biorealism Phylogenetic trees and analysis from the early days

nature.com/articles/s4158…

What's unusual is that Wu & Holmes (2020) did NOT inlcude the RdRp of SC2 in the analysis

Holmes definitely knew of the RdRp of RaTG13 (4991) and RaTG13's sequence since 2018

x.com/tlitb/status/1… Image
Image
Image
Image
Read 6 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Oct 15
🧵The Censorship of an Innocent Monkey!

by the following Western "science" websites:

@biorxivpreprint

@medrxivpreprint

and Chinese news websites:

@globaltimesnews

@PDChina

Let's see what disturbs them so much that they have to censor certain comments?
1. @biorxivpreprint August 2024 Image
@biorxivpreprint 2. @biorxivpreprint 3 years ago Image
Read 38 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Oct 6
1. Spiked: The Hunt For The Origin of Covid-19

Good news @BlueAntMedia is going to publish it

Many #DRASTIC interviews including myself 🐵

"SPIKED tells the inside story of one of humanity’s biggest & most pressing mysteries: the debate over the origins of COVID-19"

Clip 👇
2. The Making of the Documentary (20 minutes)

"Unfolding like true crime, this detective story takes us deep into clashing conspiracy theories & partisanship while exposing the dangers posed by experiments regularly taking place in the world’s biolabs"

worldscreenevents.com/premieres/spik…
3. Our film is a true crime detective thriller

"It’s about the future of biotech and the next pandemic. We wanted to make a contentious story really exciting, with twists and turns, that covers the science but with a strong dramatic structure"

broadcastnow.co.uk/broadcast-netw…
Read 8 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Sep 14
1. "Baseless" = How the Media Gaslights You

The 4Ds: Dismiss, Distract, Distort, Dismay

7 posts with video evidence of cat eating by Haitian immigrants in the comments

and this is why they hate @X

Because their lies & propaganda are exposed

Their Masters have lost control!
2. A Haitian Woman in the US speaks out

3. Haitian-American, whose family members ate cats, SPEAKS OUT against illegal migration.

Read 12 tweets
Billy Bostickson 🏴👁&👁 🆓 Profile picture
Sep 9
1. "For me with this data a lab origin is now more than likely" says @dr_louwen

Referring to ON876210 ( i think ;)



From authors of this paper (Submitted March 2020)

An Infectious cDNA Clone of SARS-CoV-2



h/t @Rebecca21951651 ncbi.nlm.nih.gov/nuccore/ON8762…
ncbi.nlm.nih.gov/pmc/articles/P…
2. From 2020 Paper

“icSars_CoV_2 retained the engineered molecular markers & did not acquire other mutations”.

@dr_louwen considers that:

1. This increases the validity of the genetic finding

2. This isolate is highly similar to the wild type isolate 2019-nCoV/USA_WA1/2020
@dr_louwen 3. Point 2 above refers to "ON876210"

(My mistake in Tweet 1)

Submitted (29-JUN-2022) in the USA

ncbi.nlm.nih.gov/nuccore/ON8762…
Read 4 tweets

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