The Good, Bad & the Ugly with @THAILANDMEDICA1
1. thailandmedical.news/news/breaking-…

Paper: COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes

insight.jci.org/articles/view/…
2. Does your Brain hurt?

thailandmedical.news/news/saudi-ara…

Paper: Brain MRI in SARS-CoV-2 pneumonia patients with newly developed neurological manifestations suggestive of brain involvement

nature.com/articles/s4159…
3. Yes, my brain hurts, doctor!

thailandmedical.news/news/breaking-…

Paper:

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

nature.com/articles/s4159…
4. Cognitive Decline and Brain Fog

thailandmedical.news/news/icahn-stu…

Paper: Assessment of Cognitive Function in Patients After COVID-19 Infection

jamanetwork.com/journals/jaman…
4. You Microclot! You Inflammatory Molecule!

thailandmedical.news/news/breaking-…

Paper: Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin

cardiab.biomedcentral.com/articles/10.11…
6. We are all effed?

thailandmedical.news/news/breaking-…

Paper: Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection
A Systematic Review

jamanetwork.com/journals/jaman…

n this systematic review of 57 studies comprising more than 250 000 survivors of COVID-19,
7. How dare you alter my Genes without permission!

thailandmedical.news/news/breaking-…

Paper: Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae

medrxiv.org/content/10.110…
8. New Variants and Mutations (1)

You can run but you can't hide..

thailandmedical.news/news/breaking-…

Paper: The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency

nature.com/articles/s4142…
9. New Variants and Mutations (2)

SARS-COV-2 gets a Break out of Jail Free Card

Hotspot Mutations and Immune Evasion

thailandmedical.news/news/swiss-stu…

Paper: Mutational hotspot in the SARS-CoV-2 Spike protein N-terminal domain conferring immune escape potential

biorxiv.org/content/10.110…
10. New Variants and Mutations (3)

Baton Rouge Mutants

thailandmedical.news/news/louisiana…

News: What do we know about the new Louisiana COVID-19 variant?

deseret.com/coronavirus/20…
11. New Variants and Mutations (4)

Don't go to Cape Cod

thailandmedical.news/news/harvard-a…

Paper: Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts

medrxiv.org/content/10.110…
12. Oi, Pfizer, did you just steal my N Antibodies?

thailandmedical.news/news/uk-health…

with useful list of 91 studies on natural immunity

Document (UK):

assets.publishing.service.gov.uk/government/upl…
13. Single agent monoclonal antibodies? Hilarious?

@THAILANDMEDICA1 puts the boot in again(Image 1)
thailandmedical.news/news/hilarious…
Paper: Acquisition & onward transmission of a SARS-CoV-2 E484K variant among household contacts of a bamlanivimab-treated patient
medrxiv.org/content/10.110…
14. One for @Daoyu15 Too complex for me.

Monoclonal Antibody Related

thailandmedical.news/news/breaking-…

Paper: Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis

biorxiv.org/content/10.110…
15. Role of Lipids

thailandmedical.news/news/universit…

Paper: The roles of lipids in SARS-CoV-2 viral replication and the host immune response

jlr.org/article/S0022-…
16. "Palmitoylation" 🤲🤦🤦‍♂️🤦‍♀️

thailandmedical.news/news/universit…

Paper: Inhibition of SARS-CoV-2 spike protein palmitoylation reduces virus infectivity

biorxiv.org/content/10.110…

"Palmitoylation of the 1st 5 cysteine residues of the spike c-terminal cysteine-rich domain are indispensable"
17. Finished with Bad & Ugly, now Good news
1. Manuka Honey
thailandmedical.news/news/qatar-uni…
2. Basil (Fenchol)
thailandmedical.news/news/fenchol-a…
3. Glucose Regulating Drugs
thailandmedical.news/news/penn-stat…
4. Zofran (Antiemetic)
thailandmedical.news/news/new-ameri…
5. Atovaquone (antimicrobial)
thailandmedical.news/news/danish,-c…
18. I hope this thread was not too depressing?

If it was, the solution is at hand, mushroom soup :)

thailandmedical.news/news/penn-stat…

Mushroom intake and depression

"Mushroom consumers had a lower odd of depression"

sciencedirect.com/science/articl…
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More from @BillyBostickson

May 22
🧵1. Another Modest Proposal

This time for the Pangolin’s Noble Sacrifice!

In this enlightened year of our Lord 2025 I, a humble observer of mankind’s ceaseless quest for health, find myself much struck by the ingenious practices of the Orient..
🧵2. A Scaly Panacea

...where the pangolin, that scaly denizen of subtropical climes, hath been elevated to a panacea most wondrous.

The Baicao Chinese Medicine compendium, a veritable gospel of herbal wisdom, doth proclaim the virtues of this creature’s scales...
🧵3. Humanity's Salvation?

...harvested with a diligence that would shame the most ardent of alchemists.

I propose, therefore, a modest scheme to amplify this noble tradition, ensuring that the pangolin’s sacrifice might serve the greater good of humanity.
Read 16 tweets
May 21
🧵🗞️The International News

A Convulsive Horizon of No Escape

Clang! Bar, far, scar, star.

Take the swarming headlines, shred them,

South Korea’s soy sauce grand master stirs

Books that don’t exist, AI’s fevered brew.

War without purpose, war crimes bite,
🧵🗞️ Clang! Crimes, limes, slimes!

EU’s chocolate crisis, cocoa beans scream!

Climate breakdown bites the fields.

The moment that changed me

a boulangerie revelation melting into Vindolanda’s stone relief

But the man in the navy suit and tie,

chokes on known unknowns.
🧵🗞️ Clang! Rice, nice, vice, dice!

Japanese minister’s rice is free, free, glee, spree,

As Trump’s tariffs tangle with toilet roll wedding lists.

No escape. The hour will no longer be ours.

Clang! Dome, home, foam, roam!
Read 38 tweets
May 16
Some insights into our DRASTIC investigation

1. What appears wasteful research to you in the present may be of great value to you or others in the future, if it is given the time to develop to its logical end.

Don’t judge the usefulness of your findings too quickly!
2. What appears wasteful or a dead end to you..

May be of immense value to somebody else!

Don’t judge the usefulness:

1. Of other people’s findings based only on your own assessment of them.

2. Of your own findings based only on your own current assessment of them either.
3. What appears wasteful and a dead end to you..

A. May be the raw stuff that new hypotheses and new research directions are born from.

B. Don’t judge the usefulness of your "investigations" until you have given them enough time to surprise you.
Read 15 tweets
May 13
🧵Holmes Studies "Lab Leak"🤔

1⃣ WIV

-Deliberate release of bioweapon
-Accidental release of bioweapon in development
-Lab accident during genetic engineering
-Lab accident during cell culture
-Lab accident during vaccine development
-Accidental infection that no one knew about
2⃣ WCDC

• Lab worker infected during field animal sampling
• Accident during experimental work
• Accident from exposure to infected waste
• Accident during move to new location
• WCDC gave bat samples to the WIV
3⃣ Virus engineering

•Engineered from RaTG13
•Engineered from pool of bat viruses (Laos)
•Engineered from secret database of bat viruses
•Engineered at UNC & shipped to the WIV
•Engineered hybrid of bat & pangolin viruses🐵
•Synthetic infectious clone engineered in vitro
Read 8 tweets
May 12
🧵THE GOOD, THE BAD & THE UGLY!

1. GOOD NEWS

Thanks to @BumblebeeJoe I have 250 new followers!



Welcome aboard!

To summarize the state of affairs in my world

As you may know, I am one very hard-working🙊

12-15 hours a day investigating "lab leak"✅
🧵2. My Recent Work

I demolished Pekar et al., (2025)

x.com/BillyBostickso…

This paper is so bad it is not even wrong!

Das ist nicht einmal falsch!

(Wolfgang Pauli)

azquotes.com/author/21450-W…
🧵3. I completed my 40,000-word final report

(Possibly final..😉)

The Pangolin (Coronavirus) Papers

x.com/BillyBostickso…

I provided summaries and explainers here:

x.com/BillyBostickso…
Read 35 tweets
May 9
“We are not a Cult”

DRASTIC and the investigative network that broke the Corona laboratory taboo

Must Read Interview!

The hard working "Two Ronnies" of DRASTIC

@gdemaneuf & @BillyBostickson

Interviewed by @franzbecchi for @berlinerzeitung

berliner-zeitung.de/politik-gesell…
1. Who are the “pandemic detectives”?

We speak with 2 of DRASTIC's prominent members:

@gdemaneuf (a data scientist & engineer)

and @BillyBostickson, longtime activist who was formerly part of opposition networks in China & HK & who operates anonymously for security reasons.
@gdemaneuf 2. My Responses

How did DRASTIC come about?

I started in January 2020, triggered by an article by Dan Sirotkin on the origins of the virus.

I connected with people like @R_H_Ebright & others on Twitter.

In May 2020, I chose the name "DRASTIC" for this decentralized group.
Read 18 tweets

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