QUICK(ISH) THREAD ON UK COVID UPDATE:

TLDR: cases dropping (partly but not wholly a half term effect), but hospital admissions & deaths rising (in England). Vax still not fast enough.

1/13
Vaccination: NI v behind on boosters *and* highest rate of unvaxxed.

England v behind still on 12-15 yrs compared to Scotland & Wales. Disappointing. 2/13
In terms of speed, boosters are getting quicker but first jabs (teens) are not (in England).

Projecting forward *current* rates, the teen and priority group booster programme won't be done till Feb.

We need to increase availability *and* demand. 3/13
Overall, cases in UK have fallen this week. Positivity rates are lagged (about a week behind), but up the time of drop were going up in England and Scotland.

Wales was declining but still *very* high positivity rate.
4/13
Looking at lateral flow & PCR tests in England, you can see the steep half term drop - mirroring what we saw in summer. On avg we're doing 150K and 20K fewer LFD & PCR tests respectively.

➡️maybe 4K cases might be being missed. Be careful of assuming it's all a real drop! 5/13
That said, cases do looked to have peaked (for now) in school age children, but not yet in adults.

However, prevelence in primary and secondary school children remains very high - 3rd week in a row that ONS shows >8% for 11-15 yrs... 6/13
Since so many infections have been school age kids, I do expect half term to break many chains of transmission and I expect to see cases in kids fall for at least another 10 days... But they might pick up again once school is back. We'll see. Disappointing low vax. 7/13
In terms of regions, both in cases and positivity, the SW is a clear outlier - doubtless at least in part due to Immensa false neg test scandal.

ONS also shows highest cases in SW - and that's randomly sampled people. 8/13
Overall people in hospital rising in all nations apart from NI. In Scotland it's not growth in overall cases but growth in adults offset by drop in kids that is driving up admissions. Waning? (graph @TravellingTabby ) 9/13
In England, hospital admissions have risen quite steeply this week. Last time we had >955 admissions was 23 February :-(

This is not good news for the NHS - and they are likely to keep rising in near future because cases in adults have not dropped (yet?). 10/13
In terms of hospital, NE & Yorkshire still bearing the brunt. Both SW and NW are rising rapidly - and clear differences in SW by Immensa...



11/13
Deaths are also now going up - over 1000 deaths last week in the UK.

Rising cases recently suggests deaths will keep rising - but hopefully boosters will at least prevent some deaths in infected vulnerable people.

I do not think current level of deaths is acceptable. 12/13
So that's that. All eyes on what happens after return to school next week - will take a few weeks to know. We do need to get teen vax *much* higher. And where are the CO2 monitors for schools now that winter is here? 13/13

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More from @chrischirp

28 Oct
SHORT THREAD: about Covid testing, system strain and potential fall out from Immensa scandal on getting PCR tests...

Am highlighting stuff from @ProfColinDavis , @fascinatorfun , @cfinnecy, @samueljlovett & @Gabriel_Pogrund

TLDR: it's not just Immensa, system is straining 1/11
When you do a PCR test, the most common result is either a positive or negative. But some tests return a "void" result, which can mean a bad sample or bad testing process.
Or an "unknown" result where the test just gets lost in the system 2/11

@fascinatorfun has pointed out that voids are more common if testing capacity is under strain - rushed tests, cutting corners on equipment maintenance or procedures etc can lead to more voids.

Tests also more likely to be lost in a straining system 3/11
Read 12 tweets
26 Oct
THREAD on IMPACT OF IMMENSA SCANDAL:

Here are case rates in 10-14 yrs for the 13 most impacted English local authorities compared to all other local authorities.

The dodgy artificially low case rates are obvious as is massive increase in spread compared to rest of England 1/6
Here are primary school age children who *weren't* doing regular LFD tests and relied much more on PCR tests for symptoms.

The two dips looks as if different authorities in that list might have been impacted at different times. 2/6
The recent increase is *not* people rushing out to get tested. The last data point is 19 Oct - the scandal only broke on 15 Oct. The increases all started before then.

It wasn't just children either - here are their parents' age group 3/6
Read 6 tweets
24 Oct
Not only does Wales have a very high case rate at the moment it also has an *extremely high* positivity rate - almost a quarter of people tested are testing positive...
Also -Welsh hospital admissions with Covid are pretty much the same as their *first wave* peak and half their Jan 2021 peak.

In contrast, England is at about a quarter of Jan peak and a third of first wave peak.
You can see a vaccine effect though - severity of illness seems quite a bit less this time around and with shorter stays (so total number in hospital lower at any one time)
Read 6 tweets
23 Oct
THREAD: overview of where we are with Covid.

TLDR: Things aren't looking great, SW hit hard by the Immensa lab scandal, admissions climbing quite fast.

Half term should help a lot in the short term. Esp if we accelerate vax. Clear case for Vax Plus. 1/20
On vaccination, home nations between 65 and 71% fulle vaxxed. Good but behind many other high income countries now.

England v slow on 12-15 rollout - 18% vs 36% in Wales & 50% in Scotland.

16-18 yr old data shows vax works 2/20
On boosters - firstly looks like Pfizer booster works phenomenally well - much higher levels of antibodies after 3rd dose and 96% reduction in risk of catching covid after 3rd dose compared to just 1 dose.

So we def want to them in people - & case stronger for under 50s? 3/20
Read 20 tweets
19 Oct
Two things stand out to me from this chart:

1. The SW is accelerating much faster than anywhere else
2. London rates are almost half those everywhere else.

1. could be driven by the testing scandal but I have no idea what is driving the lower rates in London! and... 1/2
... it's not just testing behaviours!
Positivity rates in SW are also climbing steeply (*before the scandal came out late last week).

Meanwhile positivity rates in London are *also* lower than everywhere else, so it's not just lack of testing 2/2
PS the lower rates in London are seen across the whole age range.
Read 4 tweets
17 Oct
THREAD: Some numbers on Covid and kids since 1 Sept 2020.

For 5-14 yr old kids:
Whole of Autumn term (rise of Alpha) through to spring: 239K confirmed cases.
Summer term starts low, then Delta. April - August another 285K cases.
Since 1 Sept, 336K cases *so far*. 1/7
Case ascertainment improved in March with regular testing for school kids - but even compared to summer term, numbers this term are *far higher*.

ONS infection survey (no testing bias) reported that prevalence in 2nd-ry school kids now more than 2x higher than winter peak . 2/7
What will burden of Long Covid be in children infected since summer?
ONS estimated that in 4 weeks to 2 May, 23K children ages 2-16 had persistent symptoms from Covid caught at least 12 weeks before - ie infections before mid Feb 2021.
(June dataset: ons.gov.uk/peoplepopulati…) 3/7
Read 7 tweets

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