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Tyler 🐈‍⬛Black Cat🐈‍⬛, MD

@tylerblack32

28 Oct

Really interesting RCT showing 10 days of 100mg 2x per day of fluvoxamine reduced bad COVID outcomes.

No taper start either! Just bam 200mg daily. Makes ya wonder.
thelancet.com/journals/langl…

Participants: less than 7 days of covid like symptoms or a covid+ test

n=1497, fluvoxamine vs placebo

Outcome measures: >6h in an ER or admitted to tertiary care

Results: 32% reduction in the fluvoxamine group

While the ITT sample didn't reach significance (including dropouts) for death, it should be noted that the death rate for per protocol participants was;

Fluvoxamine: 1/548 (0.18%)
Placebo: 12/618 (1.94%)
RR: 0.09 (95% CI 0.01-0.47)

90% reduction in death rate.

Read 4 tweets

Tyler 🐈‍⬛Black Cat🐈‍⬛, MD

@tylerblack32

26 Oct

@samhsagov

The 2020 @samhsagov study on youth suicidality (conducted Q4), was reassuring. Overall 12% of 12-17y kids indicated serious suicidal thinking, with 5% making plans and 2% attempting.

This is quite improved compared to @CDCgov numbers in 2019, pre-pandemic. (18%, 15%, 9%, 14-17y)

These improvements seen across the board (age+sex). Though different agencies, both reports are national representative samples. I certainly advise caution comparing the two to any great detail. At a high level, however, it's very reassuring to not see "much higher numbers" here.

I suspect that we will continue to see higher quality data emerge showing globally that children did not show increases in suicide-related measures during 2020 (which includes pandemic, lockdown measures, and everything else that year!)

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Tyler 🐈‍⬛Black Cat🐈‍⬛, MD

@tylerblack32

20 Oct

Therapists: every now and then, you should scan your patient roster, and see whether the makeup of your patient population reflects the population of people in your area. If it doesn't, for whatever reason, you are part of systemic discrimination. Yes, it will require sacrifice.

I've already seen misinterpretation.

"You are part of" does not mean "solely responsible"
"Will require sacrifice" does not mean "must work for free"

I'm sorry that the world works the way it does, but you are either someone who works to correct barriers or someone who doesn't.

Similarly, reducing your carbon footprint barely puts a dent in the climate change crisis yet doing so, while influencing others to do so, and advocating for change at every level is *necessary* to affect climate change.

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Tyler 🐈‍⬛Black Cat🐈‍⬛, MD

@tylerblack32

15 Oct

Thread Title:
"Vaccine Math for GBD Flat-Earthers"
or "Don't Be Like Kyrie"

Being vaccinated reduces your chance of infection from COVID by about 5-fold.

Consider this the "peer review" for all the 💩GBD/contrarian people who deny that vaccination prevents transmission.

/1

Hypothetical! Math!

100 unvaccinated basketball players (like Kyrie Irving) get a *significant* COVID exposure of some COVID-filled room. Some percentage (let's say for arguments sake 20%) get infected themselves.

100 x 0.2 = 20

Now we have 20 infected players.

/2

Each of these 20 players runs an elite camp with 30 unvaccinated kids (lots of indoor time, some chalk talk, etc). That's 20 x 30=600 exposures. Let's assume it follows the dynamic of the CDC report regarding spread to kids indoors. 50%.

That's 300 kids getting COVID.

/3

Read 10 tweets

Tyler 🐈‍⬛Black Cat🐈‍⬛, MD

@tylerblack32

14 Oct

@CDCgov

Suicidology Update
=-=-=-=-=-=-=-=-=

We now have 1 years (Apr20-Mar21) of the pandemic and its association with suicide rates in the US (per @CDCgov). Pretty much every month (including the most recent) showed a substantial decrease compared to the previous five years.

(1/5)

Here is the same data but comparing the sum of the past five years to the pandemic year. The overall average decrease is 4.4% compared to the past 5 years together, and 5.4% compared to the previous year.

(2/5)

There will be breakdowns of data coming soon (when Wonder is updated) re: race, age, and gender.

I will get this data out as quickly as I can & visualize it in a way that puts it into context. Media people would do well to follow my example and include historical context.

(3/5)

Read 5 tweets

Tyler 🐈‍⬛Black Cat🐈‍⬛, MD

@tylerblack32

1 Oct

It's a sad graph for UCSF contrarians and medpage today editors, but a good day for everyone else. Unequivocally, there is significant benefit *EVEN WHEN CONSIDERING THE MILD MYOCARDITIS* to using vaccines in adolescents.

yourlocalepidemiologist.substack.com/p/todays-acip-…

cdc.gov/vaccines/acip/…

you can get the whole meeting slides here yourself!

for 18-24 year olds

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Tyler 🐈‍⬛Black Cat🐈‍⬛, MD

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