Just a friendly reminder. Despite what you might hear, there has yet to be a variant that isn’t susceptible to the vaccines.
Why are variants unlikely to FULLY evade vaccine-induced immunity?
•Vaccines are polyclonal
•CD8+ T-cells covering 52 epitopes across the spike protein
•CD4+ T-cells covering 23 epitopes across the spike protein
You can learn about epitopes here: news-medical.net/life-sciences/…
Regarding the concerns about waning immunity. Please remember, this is likely referring to infection. Not effectiveness against symptomatic infection, not effectiveness against severe illness. See: bmj.com/content/374/bm…
While neutralizing antibodies decrease over time (as they ARE supposed to) protective immunity provided by memory B-cells and T-cells is STILL present. See: science.org/doi/10.1126/sc… and biorxiv.org/content/10.110…
The term infection refers to the virus entering and being detectable in your system regardless of whether OR NOT it makes you sick, whereas the term illness refers to the virus entering, being detectable in your system AND making you sick. It it important not to conflate the two.
The first thing to know about the COVID-19 vaccines is that they’re doing exactly what they were designed and authorized to do. Since the vaccines first started their rollout late last year, rates of COVID-19 disease have taken an unprecedented plunge among the immunized.
The second thing to know about the COVID-19 vaccines is that they’re flame retardants, not impenetrable firewalls, when it comes to the coronavirus. Some vaccinated people are still getting infected, and a small subset of these individuals is still getting sick-
-and this is completely expected. Read here: theatlantic.com/science/archiv…. Your Vaccinated Immune System Is Ready for Breakthroughs. Read here: theatlantic.com/science/archiv… and theatlantic.com/science/archiv…
If you find the time this week, consider reading:
•Six Important Things to Know About “Breakthrough” Infections: smithsonianmag.com/science-nature…
•America Has Lost the Plot on COVID: theatlantic.com/health/archive…
•A Better Way to Think About Your Risk of COVID: theatlantic.com/science/archiv…

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More from @sailorrooscout

5 Nov
FANTASTIC news for your Friday! Phase 2/3 results of PAXLOVID, Pfizer’s COVID-19 oral antiviral shows the risk of hospitalization or death is REDUCED by NEARLY 90% in high-risk adults with COVID-19 when taken within three days of experiencing symptoms.

Let’s talk about that! 🧵
IMPORTANT NOTE: this protease inhibitor was originally developed for SARS-CoV in 2003 and has been repurposed! So first, let’s discuss the results. The scheduled interim analysis showed an 89% reduction in risk of COVID-19-related hospitalization or death from any cause compared
to placebo in patients treated within three days of symptom onset (primary endpoint); 0.8% of patients who received PAXLOVID™ were hospitalized through Day 28 following randomization (3/389 hospitalized with NO deaths), compared to 7.0% of patients who received placebo and
Read 14 tweets
3 Nov
How’s your morning going? Image
This is how I started my birthday.
Update. The Dinosaur- I mean, uh, the bird has been successfully contained.
Read 4 tweets
2 Nov
“The vaccines don’t work- look at Singapore.” Alright, let’s.

Cases are at record highs due to Delta, however, ALMOST 99% of Singapore’s vaccinated cases are MILD or have NO symptoms. In addition, the nation has had VERY FEW deaths despite a surge in cases.

I’m not done.🧵
Almost 84% of Singapore’s population is considered to be fully vaccinated. IMPORTANT TO NOTE: Singapore transitioned away from a ZERO COVID approach. The rise in cases upon attempting to reopen was to be expected as part of attempting to “live” with the virus and reopen.
According to their MOH, over the last 28 days, of the 96,376 infected individuals, 98.7% are MILD or have NO symptoms, 0.8% required oxygen supplementation, 0.3% required ICU care, and 0.2% had died. moh.gov.sg/news-highlight…
Read 14 tweets
29 Oct
Let me fix this BBC headline for you since most unfortunately will not read past it, OR even read the study. Fully vaccinated individuals can contract and pass on COVID-19 in the home, BUT AT LOWER RATES than unvaccinated individuals. bbc.com/news/health-59…

I’m not finished.🧵
If you actually open this article, rather than just posting a screenshot of it and taking it as some sort of sarcastic “win” as I have seen several people do this morning, you will find that this article does not really say what you think it says and I think most people
are counting on the fact most will not read past the headline. So, what does it actually say? First and foremost, and from the author of the study themselves: “The ongoing transmission we are seeing makes it ESSENTIAL for unvaccinated people to get vaccinated to
Read 14 tweets
27 Oct
A study of 1M+ people in Canada found two doses of any of the three COVID-19 vaccines (Moderna, Pfizer, AstraZeneca) led to strong protection from infection, hospitalization, AND death -even against Delta- REGARDLESS of the vaccination combination and showed NO signs of waning.🧵
Data from researchers at the British Columbia Centre for Disease Control (BCCDC) and the Quebec National Institute of Public Health (INSPQ) showed two doses of mRNA and/or AstraZeneca’s vaccine gave excellent protection against hospitalization, with NO SIGN of decline
by 5-7 months post-vaccination. In addition, a 7-8-week interval between doses improved vaccine efficacy and may be optimal in most circumstances. Findings indicate prolonged two-dose protection and support the use of mixed schedules and longer intervals between doses.
Read 14 tweets
25 Oct
In case it needs to be said, COVID-19 vaccines DO NOT and WILL NOT cause AIDS. This false claim has been circulating due to the manipulation of documents which DO NOT even mention anything of the sort in their original text. Stop the misinformation.
Please remember, the risk of developing aids comes through infection with HIV, which can occur from exposure to infected bodily fluids OR by sharing needles with someone who is infected.
At NO time will your immune system weaken due to the COVID-19 vaccine or any vaccine for that matter. Vaccines encourage and train our immune systems, not the opposite. In addition, please remember, neutralizing antibodies always decline, AS THEY ARE SUPPOSED TO! But guess what
Read 7 tweets

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