NK Leb #UpdateTheVaccines 💉 Profile picture
Nov 14, 2021 8 tweets 3 min read Read on X
The morons are at it again.

"What makes more sense"?

There are only two options. 3rd dose or no 3rd dose.

In what reality does not taking a vaccine make more sense than taking one?

None. Makes no immunological sense.
What difference does it make?
"Exhaust your immune system" has entered the chat.
It isn't, though. None of this is new.

There are zero immunologists working day and night watching The Simpsons reruns trying to decode "The Paradox" to figure out boosting at 6 months vs 1 year.

This is just a question for blue checkmark PH accounts on Twitter.
"Experts all agree" - no.

What is being described below is the very basis of "herd immunity" that had been promoted for over a year, for this very pathogen, whereby the immune protect the non-immune by breaking transmission chains.
The privileged have antivirals, monoclonals, dex and ECMO machines and everything in between.

The more vulnerable only have these free vaccines. Not even PTO to take them.

These people want to take away the only thing the vulnerable have.

In the name of the equality.
So what else can the individual do other than take a vaccine or wear a mask?

They are still at risk, sure, but the vaccine reduces the risk and you're not proposing any alternatives.

You're saying "the risk is still there, so don't take the vaccine."
Vaccination does two things:

1. Herd immunity: vaccinate oneself to protect the non-immune
2. Individual protection: vaccinate oneself to protect oneself.

These  🤡🤡 are against both. Against boosting to reduce transmission & against it to reduce individual risk.

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More from @NickytaLeb

Jan 26, 2022
Oh. Image
Citation? Image
Hmm.. weak vaccines, non-equipped health care system.

Maybe, just maybe, that's why they're doing what they're doing?
Have yous considered it?

@ZekeEmanuel @mtosterholm Image
Read 12 tweets
Jan 11, 2022
Some of y'all may think I'm obsessed with older tried-and-true vaccine platforms such as inactivated or attenuated virus vaccines when we have mRNA.

The problem is that most countries don't have mRNA & can't make any vaccines whatsoever, dependent on old, weak shots from China.
It's a disaster that many parts of the world will not be able to take a virus, influenza or CoV-2 strain, and inactivate it and use that as a vaccine.

This is the 2nd pandemic where low income countries see that centralized vaccine production does not work in their favor.
Spoiler alert: there will be another respiratory virus pandemic in the future.

Spoiler 2: one will be able to create a vaccine for it by inactivating the virus + adjuvant or inhaling a cold-adapted attenuated strain of it.

And low income countries will die waiting for Moderna.
Read 4 tweets
Jan 11, 2022
This dumb idea of "fear" causing the disruptions has to stop.

Restaurants near me that were open during the WT, Alpha & Delta waves are now (temp) closed because they have no staff. Lots of places with no temps.

This has nothing to do with "fear" of Omicron.

Folks just sick.
This has nothing to do with "overtesting" - since he have no access to any tests whatsoever (no PCRs, no rapid tests) or isolation policies (no tests = no cases = no isolation).

People are just sick in bed with "flu-like symptoms"

I don't know what to tell you.
This dumb idea that systemic T cells will prevent people from getting ill and that once all of us get these magic spike protein-targeting T cells in our blood that disruption will never happen again and that we can go back to treating this like OC43... turned out to be dumb.
Read 14 tweets
Jan 7, 2022
Next winter we could absolutely have COVID-19 have a "flu-like" or "less-than-flu" impact on hospitalization & mortality.

It just requires better vaccination (strain match) like the flu, preemptive vaxxing in Autumn (like the flu), vaxxing kids (like the flu)... you get my point
The ideal vaccine would be a recent, strain-matched vaccine that elicits mucosal antibodies & tissue resident B/T cells.

Every step away from that reduces VE:

1. Time since vaccination
2. Strain mismatch
3. Route (systemic vs local antibodies immune cells)

We're at 0/3 today
With 2-year-old vaccines targeting a distant relative of the circulating strain, eliciting systemic antibodies and immune cells, and this vaccine being administered 6-months to a year ago, what we are seeing is a recipe for failure.

This is a 0/3.

We don't do this for the flu.
Read 15 tweets
Jan 6, 2022
Just a reminder to all the "the vaccines were made to prevent severe COVID or death" losers is that moderate COVID has these symptoms, including "deep-vein thrombosis" which is very serious but still considered "moderate" for the trials.
A vaccine for a respiratory virus that does not prevent "pneumonia" is a failure. A vaccine that has does not prevent these listed symptoms is simply a failure and one must reformulate the shot to match the strain, or reconsider dose, schedule or route or the platform itself.
Fortunately for us, the vaccines in the trial prevented moderate COVID-19, as well as "symptomatic COVID-19."

Unfortunately for us, many have decided to shift goalposts & gaslight everyone, claiming that the trials were for severe COVID & death & that everything else is mild.
Read 4 tweets
Dec 3, 2021
This is a biphasic disease - a viral phase & an immunopathological one.

There may be 𝑠𝑜𝑚𝑒 virus in the 2nd phase & there is 𝑠𝑜𝑚𝑒 immunopathology in the 1st, & there can be rapid deterioration/cascading of 1st into 2nd, but many only experience one phase.

Biphasic.
The ancestral strain of SARS-CoV-2 had a relatively mild viral phase and a possibly terrible 2nd phase. People felt mild flu-like symptoms in before rapidly deteriorating.

Subsequent variants have resulted in increased virulence, with the 1st phase being more severe, esp. Delta.
Animal challenge trials, even in macaques, show only the first phase. Even unvaccinated animals only experience 7 days of a typical respiratory illness and that's it.

COVID-19 in humans is different.
Read 4 tweets

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