Mark Honigsbaum's review of Viral by @Ayjchan and @mattwridley is rather disappointing.

Out of a lack of analysis, likely aided by an authoring bias, @honigsbaum has produced a damp squib, when usually his writings are much better.

theguardian.com/books/2021/nov…
The opening sets an unfortunate political tone, which is rather trite and totally unnecessary, unless Mark aims to please a political tribe instead of going through a rigorous review:

"Ridley, a Conservative hereditary peer.."
Is Matt now guilty of being born?

Very fancy ideas about hereditary responsibility here for a science writer. The last time this was fashionable it did not work out very well.

Seriously, it's better to abstain from taking cheap political swipes at someone.
Then we get the predictable '...best known for his sceptical writings on climate change'.

You do not have to be a climate change denier (and I could not be further from that) to note that this is a cheap 'framing' trope at the very start of a review.
Now the book is not about climate change - so this is rather a silly trick of the reviewer's trade.

By the way, if the same all-or-nothing criteria was applied to the Chinese government, given all its lies and abuses, Mark should not ever believe anything that China says.
Then Mark happily resorts to a strawman argument, focussing on only one research-related scenario, the one of a manufactured virus.

This is a complete reduction of a range of plausible research-related scenarios that include a sampling infection and natural viruses in a lab.
Is that laziness or another cheap trope?

This is compounded by yet another strawman argument on whether RaTG13 could be a SARS-CoV-2 progenitor.

Very few people argue that point. As explained before, RaTG13 is interesting for other reasons.
All this slow gradual buildup, punctuated by various tropes, then delivers a complete damp squib when Mark eventually wreaks his boat on some basic logical mistakes.

So the Laos finding 'suggests it most likely emerged naturally'.
An absurd reasoning since ALL research-related scenarios (sampling accident, natural virus escape, escape of a construct) suppose that the virus (or its backbone) is present in nature!

Where is common sense gone?
And all the more a suspicious reasoning since it completely fails to explain how that virus ended up triggering a breakout in Wuhan AND NOWHERE ELSE.

Clearly Mark has problems grasping the probabilistic consequences of the location exclusivity argument.
While at the same time we now know that EHA was planning to sample in Laos in 2017-19 and send everything to the WIV.

Mark should acknowledge that the Laos findings do not move the needle and are perfectly consistent with zoonotic and research origins.
So much for the 'most parsimonious' 'farmer [who] ventured into a cave in Yunnan or Laos in search of guano'.

I guess that the farmer went shopping in Wuhan as many must do.

And. God forbid!, he certainly did not meet a WIV sampler in his village.
As for the 'epidemiological evidence' Mark goes fully in, with his claim that 'most of the original human cases had a history of prior market exposure'.

Actually no.
3 of the 4 earliest official ones had none. And we now nothing of all the November cases that China has hidden.
In any case, the earliest official case (Mr Chen) - whom China could not hide because it became the case reported by the Ai Fen and Li Wenliang - lived in the urban district closest to the WIV and shopped locally at a modern supermarket.

Even the Chinese did not believe the wet market story, starting by Chinese scientists who published a very good paper on the 21st Feb 2020.

Did you check that paper @honigsbaum ?

Even Gao Fu, the Oxford-educated director of the China CDC, eventually conceded that it was most likely just a superspreader event.

Did you miss that @honigsbaum, or where you too busy fixating on hereditary peers?
globaltimes.cn/content/118950…
To make things worse Mark doubles up with the now totally discredited story of pangolins as potential intermediary species.
For your info Mark, the outspoken HK virologist Yi Guan recently asserted that the pangolin story was disinformation and that the research-related accident was on the table.

How do you deal with that?
Mark then heads again for the rocks, this time the rocks of the triply false generalisation:

"No major pandemic has ever been traced to a laboratory, whereas history is littered with examples of pandemics that began as transfers of viruses from animals."
By the way, I am actually quite amused to see how Mark took a swipe at Matt for being an hereditary peer, but subscribes to a faulty 'hereditary' views of pandemics without applying any logical filter.

Sweet irony.
Matt closes his review with another cheap trope of the writer, basically the closure on the Climate Change theme labored in the opening:

"far more urgent and compelling story of how the trade in wild animals, coupled with global heating and the destruction of natural habitats"
Which is obviously another way to try to frame Matt (and poor Alina) as Climate Change deniers, and have the readers reach for the sick bag.

Seriously, that Guardian review was very poor and Mark should do better.

@Ayjchan @mattwridley @thackerpd @natashaloder @fastlerner

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More from @gdemaneuf

16 Nov
One should add Mark Honigsbaum’s recent article in the Guardian to the list of politically motivated disinformation pieces that abuse the Laos findings:
Read 4 tweets
10 Nov
There are a lot of fallacies peddled by 'experts' when they tell you that based on an historical argument, the most likely explanation for Covid-19 is a zoonosis and not a research-related accident.

sandwalk.blogspot.com/2021/10/the-ca…
1/ Cargo Cult:
First, it is interesting to note that some of these experts happily follow a kind of cargo cult whereby sampling left and right on an industrial scale and tweaking viruses will get you to eco-health nirvana..
all achieved by bringing science to dark corners of the world, educating local populations, fighting bad local habits and the like. (Wait, did I read that somewhere else?)

And so one can go sample in some caves in these 'wild' places, occasionally with minimal PPEs, and bring..
Read 26 tweets
10 Nov
Get ready for the long awaited sequel, starring Marion Koopmans and many of the original actors, plus some emerging talents such as Summermatter.

Chinese production, US financing.
Due to some unexpected problem with the casting, Daszak was unfortunately not available for the new production.

We will miss his bumbling gruffness and natural sense of comedy, but watch for the new names - plenty of great talents there:
Anyway, it looks like the someone took a leaf from the "Second China-U.S. Workshop on the Challenges of Emerging Infections, Laboratory Safety and Global Health Security" (May 2017)
Read 6 tweets
5 Nov
Page 79 of the White Coat Waste Project FOAI doc is very interesting.

I'll just put it here with my notes in red. Read these first.
@MaraHvistendah @fastlerner
@AndrewKerrNC @anthonybellotti
The bat sampling is for markets AND surrounding caves & forest:
So it definitively includes wild-caught bats too:
Read 22 tweets
4 Nov
People are starting to talk about the likely real death toll for Covid-19, centered around 12 mln.

Detailed estimates have been available for months.

But, by and large, the media tend to stick to the 5 mln number which is way below actual.

fb.watch/935ITt8kS-/
Why stick to the 5 mln when it is very clear that there is dramatic underreporting in many countries, especially developing ones?

Is it because people prefer to report a very wrong number that is supposedly precise, instead of fairly spread estimate that is way more correct?
Thus effectively gaining an illusory precision at the cost of a massive bias..

Or because it comes from country officials. Effectively trading critical thought for some official backing.

The role of media is to question numbers, no to go for the blatantly wrong & easy solution.
Read 6 tweets
3 Nov
That recent letter from the Committee on Energy and Commerce to Collins is really worth reading

Some very interesting revelations about four highly relevant letters between NIH and EcoHealth discussing EcoHealth’s research proposal.

republicans-energycommerce.house.gov/wp-content/upl…
Letters which have not been made public (why?) but for which HHS arranged an 'in camera' review of printed copies by a bipartisan Committee, at HHS headquarters on Oct 5 and monitored by HHS staff.

See particularly pages 6 and 7:
What they show is how easily EHA argued that their research objectives did not constitute GoF, against the initial concerns of the NIH.
Read 9 tweets

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