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Dr. Doug Corrigan

26 Nov, 13 tweets, 3 min read

1/One of the most concerning things about the constellation of mutations found in Nu is the abnormal combination of deletions and insertions in the N-Terminal Domain (NTD) of Spike. The NTD region is considered the hot spot for enhancing antibodies, which is connected to ADE.

2/ nature.com/articles/s4159…

3/ pubmed.ncbi.nlm.nih.gov/34384810/

4/ biorxiv.org/content/10.110…

5/ biorxiv.org/content/10.110…

6/ cell.com/cell/pdf/S0092…

7/ journalofinfection.com/article/S0163-…

8/ researchgate.net/publication/35…

9/ biorxiv.org/content/10.110…

10/ sciencedirect.com/science/articl…

11/ NTD Mutations are shown on the left (light blue)

12/ List of mutations occurring in the Spike. This is an incredible number of mutations; a number not observed in any previous variant.

13/ A67V, Δ69-70, T95I, G142D, Δ143-145, Δ211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F

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More from @ScienceWDrDoug

Dr. Doug Corrigan

@ScienceWDrDoug

28 Nov

1/ The current mRNA vaccines use an abnormal substitution for uridine; every U is replaced with m1Ψ (N1-methylpseudouridine). This synthetic substitution was made to increase mRNA stability, reduce immunogenicity, and increase expression. But what are the health effects of m1Ψ?

2/As an example, the human protein EMG1 is a pseudouridine N(1)-methyltransferase that methylates pseudouridine at position 1248 in 18S rRNA. It’s also involved in 40S ribosomal subunit biogenesis. Will m1Ψ from the vaccine inactivate this enzyme?
genecards.org/cgi-bin/carddi…

3/ If so, what cell types will this inactivation take place, and for how long? What are the implications for ribosomal assembly and protein synthesis in these cells?

Read 7 tweets

Dr. Doug Corrigan

@ScienceWDrDoug

24 Nov

1/ The authors make a strong case that AXL (UFO) is a primary receptor for viral entry, perhaps even more so than ACE2, especially in certain tissue types. Could some of the side effects associated with Spike-expressing vaccines be due to Spike interacting with AXL? Fertility?

2/ Uniprot entry describing the function of AXL in signal transduction. Pay attention to modulation of thrombotic and platelet activity, and endothelial survivability.
uniprot.org/uniprot/P30530

3/ Also, AXL is involved in neuronal development and survivability of GnRH neurons, which are responsible for the release of Gonadotropin-releasing hormone (GnRH). GnRH controls reproductive cycle in the female and spermatogenesis in the male.

pubmed.ncbi.nlm.nih.gov/18787040/

Read 6 tweets

Dr. Doug Corrigan

@ScienceWDrDoug

21 Nov

1/ The PULS blood test analyzes a series of bio markers related to the leading cause of myocardial infarction (CHD). These bio markers are significantly elevated for at least 2.5 months post second jab, putting people at more than twice the risk of Acute Coronary Syndrome (ACS).