Here are 5 nutritional supplements which can be effective for benzo withdrawal.
At the cellular level, withdrawal appears to involve:
- Structural changes in the GABA-a receptor
- Loss of sensitivity to GABA
- Rebound glutamate excitoxicity
Explanation in following tweets...
At the cellular level, withdrawal appears to involve:
- Structural changes in the GABA-a receptor
- Loss of sensitivity to GABA
- Rebound glutamate excitoxicity
Explanation in following tweets...
1) Agmatine is a metabolite of arginine which modulates NMDA receptor function.
A recent study on benzo withdrawal demonstrated:
-Significant reduction in symptom scores
- Increased GABA
- Lower glutamate
- Major improvement across the board
#benzo withdrawal
A recent study on benzo withdrawal demonstrated:
-Significant reduction in symptom scores
- Increased GABA
- Lower glutamate
- Major improvement across the board
#benzo withdrawal
2) Niacin has long been studied in Russia for its benzodiazepine-like qualities and ability to balance brain chemistry.
- Niacin & NAD precursors possess anti-anxiety and inhibitory neurological effects
- Modulate GABA receptors
-Nicotinamide shown to improve #benzo withdrawal
- Niacin & NAD precursors possess anti-anxiety and inhibitory neurological effects
- Modulate GABA receptors
-Nicotinamide shown to improve #benzo withdrawal
3) The neurosteroid allopregnanolone (ALLO) was shown to abolish #benzo withdrawal and improve tolerance.
- Oral pregnenolone (ALLO precursor) 400mg per day can increase ALLO levels in brain 7-fold.
- Palmitoylethanolamide also increases ALLO through PPAR-a dependent mechanism
- Oral pregnenolone (ALLO precursor) 400mg per day can increase ALLO levels in brain 7-fold.
- Palmitoylethanolamide also increases ALLO through PPAR-a dependent mechanism
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