Fantastic news. Initial lab studies show a third dose of Pfizer’s COVID-19 vaccine neutralizes Omicron. A booster with the current version of the vaccine RAISES antibodies 25-FOLD providing a similar level as observed after two doses against the original virus and other variants!
As 80% of epitopes in the spike protein recognized by CD8+ T-cells are not affected by the mutations in Omicron, two doses MAY STILL induce protection against severe disease.
Blood plasma from people immunized with two doses of the vaccine had a 25-fold reduction in neutralizing antibody levels versus Omicron, when compared with the original strain of the virus, boosters RESTORE that loss.
Pfizer continues to advance the development of a variant-specific vaccine for Omicron and expect to have it available by March 2022 in the event that an adaption is needed to further increase the level and duration of protection.
“It’s clear from these preliminary data that protection is improved with a third dose,” Pfizer Chief Executive Officer Albert Bourla said in a statement. The initial data show a third dose could offer still offer enough protection from disease, BioNTech CEO Ugur Sahin said.
I’ll post the data as soon as we have it. In the meantime, you can read this and more here:
•bloomberg.com/news/articles/…
•pfizer.com/news/press-rel…
•bloomberg.com/news/articles/…
•pfizer.com/news/press-rel…
•This is in regards to INFECTION
•No going back to “square one”
•THIS IS NOT VE %, just nAbs
•Boosters are ESSENTIAL
•Steer clear of those suggesting vaccines are rendered useless based on early lab data
•Most IMPORTANT evidence to look out for is VE based on CLINICAL DATA
•No going back to “square one”
•THIS IS NOT VE %, just nAbs
•Boosters are ESSENTIAL
•Steer clear of those suggesting vaccines are rendered useless based on early lab data
•Most IMPORTANT evidence to look out for is VE based on CLINICAL DATA
From Pfizer, three doses neutralize Omicron! LOOKS VERY similar to what we see with Delta here: nejm.org/doi/full/10.10… Stay calm. Stay vigilant. Breathe and Get Boosted! pfizer.com/news/press-rel… 
“Study of blood samples in a laboratory is not proof of how the vaccines will perform in the real world. While antibodies are the first line of defense against infection, they are only part of a wider-ranging and powerful response by the immune system.”nytimes.com/2021/12/08/hea…
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