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Eric Feigl-Ding Profile picture
@DrEricDing
Dec 11, 2021 • 14 tweets • 8 min read • Read on X
📍NOTA BENE—a “mild but faster” virus will often kill & harm more people than a virus that is slower & more severe. Even if just 2x more transmissible & 1/10 less deadly! ➡️Folks who call #Omicron “nature’s vaccine” need to stop the public endangerment. Figure by @GosiaGasperoPhD Image
2) And we believe #Omicron is not just 2x more contagious but likely 3-4.5x by some estimates.
3) seriously— #Omicron contagiousness (combination of transmission and evasion against past immunity) is at least 3-4x if not even higher than Delta. Image
4) furthermore, I haven’t seen any good data that #Omicron is truly much milder. South Africa’s new wave is younger than past waves. The hospitalization rates often haven’t been age adjusted, vaccine prevalence adjusted, past infection prevalence adjusted, etc. 🍎 to 🍊.
5) Also the “mutations make a virus milder” is often not supported. With exception of one virus, most viruses like Ebola, Zika, or chikungunya viruses have “shown no signs of becomes less pathogenic”
6) Let’s compare old May wave (blue) versus the new #Omicron wave (in orange) of hospitalizations by age group in Tshwane epicenter. Notice how disproportionately it’s sending over 6x more kids age 0-4 to hospital in the first two weeks of each wave. 👀 Image
7) Bad news is the UK 🇬🇧 is facing a substantial wave of #Omicron infections in January without further restrictions, according to scientists. The researchers said tougher restrictions may be needed to prevent Omicron overwhelming hospitals. #COVID19 bbc.com/news/uk-596210…
8) Let the Netherlands 🇳🇱 be a lesson of what not to do… they basically let the virus rip. And this is the result… huge excess deaths again, close to last year’s peak. And this wasn’t even #Omicron contagiousness.
9) Why do I feel like many of us are in denial about #Omicron? I get we are all tired. I’m so darn tired. But #COVID19 doesn’t get “tired”— the virus has an evolutionary drive to mutate and play dodgeball with our immune system. We must be vigilant and keep up. Don’t be blasé.
10) Wait, I thought someone last year said “kids are practically immune to COVID”…. Hmmmm, maybe the precautionary principled epidemiologists are right and the pure economists are wrong again? 🤷🏻‍♂️
11) Another key thing to stopping spread is to drop the 6 foot is enough delusion. The virus is airborne folks. 6 feet (2 meters) is minimal safety
12) AGE ADJUSTMENT is lacking in a lot of #Omicron graphs, as well as vaccine or infection adjustment, vs past waves. But if we stratify on age (one method of adjustment), notice how hospitalizations are higher in kids in first 2 weeks. Lower in adults likely cuz of more vaccines Image
13) WARNING: Objects in the #Omicron Severity Mirror may appear milder than they (actually) are… think like an epidemiologists— think of confounders (like age and vaccine and infections) & think of such modifiers of severity have have changed over time that hide true severity.👇
14) don’t rely on past infection or 2 shots to prevent COVID alone. Definitely get the booster. The data is pretty alarming on how evasive it is. There’s no sugar coating it. 👇

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More from @DrEricDing

Eric Feigl-Ding Profile picture
Feb 26
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain. Image
2) Folks who follow me know that I’m no bullshitter. I criticized past pandemic response right and left, and have called balls and strikes without bias. And I often say things that doctors & epidemiologists are whispering among themselves but don’t say publicly. (Cough cough) ⬇️
3) While I don’t recommend hoarding… I think stocking up on flu antivirals, which you can obtain prophylactically (preventively) from doctors if you ask nicely why you’re high risk, can be a good idea. I know many doctors, epidemiologists and virologists who do for their family.
Read 6 tweets
Eric Feigl-Ding Profile picture
Feb 26
Doctors are debunking RFK Jr’s claim that 20 hospitalized measles cases in Texas are there for mainly quarantine. Doctors on the ground say the 20 kids hospitalized are having trouble breathing. Oh and they are all unvaccinated against measles, which RFK Jr neglects to mention. Image
2) RFK Jr told Trump today there’s now 2 measles deaths.
3) RFK Jr is a tear with his FDA today. A dark Darwinian future lies ahead for America.
Read 4 tweets
Eric Feigl-Ding Profile picture
Feb 26
BREAKING—Reports coming in about potentially *2 measles deaths* in Texas, not just one, according to an HHS briefing to the White House today.
2) Earlier today, one measles death in an unvaccinated child was reported in Texas. Image
3) It seems to be RFK Jr who said it in an official Trump WH cabinet meeting today. Not saying he doesn’t lie, but he is now HHS Secretary
Read 6 tweets
Eric Feigl-Ding Profile picture
Feb 21
Woke or biology? There are actually more than the basic “male” XY & “female” XX sexes. Why? Because biology also creates people with single X chromosomes, or extra chromosomes like XXX, XXY, XYY, or XXX+, plus many 🧬genes. 👉All I’m asking is— please be kind to others. Thanks🙏 Image
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2) “The most frequent SCAs include Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Trisomy X syndrome (47,XXX), and Double Y syndrome (47,XYY).”

pmc.ncbi.nlm.nih.gov/articles/PMC10…
3) “The phenotype seen in SCAs is highly variable and may not merely be due to the direct genomic imbalance from altered sex chromosome gene dosage but also due to additive alterations in gene networks and regulatory pathways across the genome as well as individual genetic modifiers.”
Read 5 tweets
Eric Feigl-Ding Profile picture
Feb 16
I'm shocked a lot of doctors don't know about this newer flu antiviral drug called Baloxavir (XOFLUZA)... that shortens your flu illness by 33%, and reduces your viral load by day 2, versus what a placebo takes 5-6 days to achieve. Baloxavir also seems superior to TAMIFLU (oseltamivir) for smashing your viral load on 2 day, achieving what takes Tamiflu 3-4 days. CDC even lists Baloxavir on their website as one of the top 4 drugs that it tracks whether it works against new flu strains (it works)Image
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2) "Baloxavir was associated with significantly more rapid declines in infectious viral load than placebo or oseltamivir (Figure 3A and 3B)."
nejm.org/doi/full/10.10…
3) Adverse events for baloxavir were no different than placebo. in fact theres even hints that it could be lower than Tamiflu.

"Adverse events that were considered to be related to the trial regimen were more common in oseltamivir recipients (8.4%) than in baloxavir recipients (4.4%, P=0.009)"Image
Read 13 tweets
Eric Feigl-Ding Profile picture
Feb 14
⚠️WORST FLU SEASON ever since 2002-2003 when we began to track flu (red, first graph). Worst hit this year are children ages 0-4 and 5-17. ▶️We also have significantly LOWER flu vaccine uptake this year, one of the lowest flu vaccine coverages (red 3rd graph). Indisputable facts. Image
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2) I don't need to tell you that certain US states have vastly lower vaccination rates than others. See map (lighter green, less flu vaccination coverage), and which have higher (darker green)...

If you want to see details and demographics on which state has the LOWEST flu vaccine coverage rates... the data is here.
cdc.gov/fluvaxview/das…Image
3) It’s not just the flu that is going around… Gaines County, TX, where the epicenter of the measles outbreak is, has one of the lowest measles vaccination rates too.
Read 7 tweets

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