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14 Dec, 4 tweets, 2 min read
BIG NEWS

The paper has been retracted. Retraction notice not yet online nature.com/articles/s4159… Image
Ping @RetractionWatch
Also, worth noting that in this whole process the editors of Scientific Reports have been really good. The faults lie with the system, not individuals, who mostly appear to genuinely care about science and evidence
I'd actually say this is an amazing piece of integrity for the editors - the paper and critiques were sufficiently academic and mathy that they could've just published all the letters and left it at that; instead, they decided the paper was untrustworthy and retracted

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More from @GidMK

Health Nerd Profile picture
16 Dec
Another new ivermectin study out recently. Apparently it is quasi-randomized and proof that suppressing ivermectin is a "crime against humanity"

Let's do some twitter peer-review 1/n
2/n The preprint is here, and it's a retrospective analysis of routinely collected clinical registry data from the city of Itajai in Brazil

researchgate.net/publication/35…
3/n The design was very simple - take routine data on people who either had or had not elected to be part of an ivermectin distribution program, and controlled for a small number of confounding variables using either a propensity-score or regression model ImageImageImageImage
Read 21 tweets
Health Nerd Profile picture
15 Dec
I do find the impact of ivermectin on people's basic critical thinking quite fascinating. This article is filled with obvious, easily checkable lies, but just look at the popularity Image
The primary claim is that an ivermectin researcher, Andrew Hill, received a grant for $40mil in exchange for lying about ivermectin Image
This claim centers around a grant awarded by UNITAID to the University of Liverpool for $32mil (the article incorrectly states $40mil) - UNITAID released a press release on the 12th of Jan, the preprint was published on the 8th. Dodgy, right? ImageImage
Read 9 tweets
Health Nerd Profile picture
13 Dec
One of the more hilarious things that the ivermectin crowd is currently doing is equating any funding ever received by the Gates Foundation as being purchased personally by Bill Gates
For example, @UNITAID. Various bizarre claims have been made that any funding from Unitaid is equivalent to receiving a personal bequest from Bill Gates
However, even a very cursory examination shows that the Gates Foundation contributes only a tiny fraction of the Unitaid budget. The main funder is France, followed by the UK
Read 8 tweets
Health Nerd Profile picture
7 Dec
Today, our letter about a paper in Nature Scientific Reports that claimed to find no evidence that staying at home reduced Covid-19 deaths was published

This is a depressing example of how scientific error-correction fails 1/n nature.com/articles/s4159…
2/n The original paper came out in March, amid the huge worldwide epidemics, and was immediately a massive hit. After 9 months, it has been accessed nearly 400k times and has one of the highest Altmetric scores of any paper ever Image
3/n The paper has also been, I think it's fair to say, one of the more impactful pieces of work during the pandemic. It is still regularly cited everywhere to support the idea that government restrictions against Covid-19 don't work ImageImage
Read 18 tweets
Health Nerd Profile picture
3 Dec
Abortion statistics are a fascinating example of bias, because there are a great many misconceptions about abortion that are nevertheless common

Try and answer the following questions without looking them up
(I'm using mostly US/EU/Aus stats here, while some of this is generalizable to other places, many of the stats will be very different particularly in low-income regions. Also, even within similar countries these stats can be quite different, so this is very general)
1. What is the most common age-group for people who have induced abortions?
Read 15 tweets
Health Nerd Profile picture
1 Dec
The most important work that I've done this year - we found that the IFR of COVID-19 is double as high in developing countries compared to high-income places medrxiv.org/content/10.110…
(The graph above is a new figure that will soon be in the updated medrxiv preprint)
As you can see from the figure above, this difference is largest in young people and tapers off in the elderly. By age 80, the IFR is only 1.3x higher in developing countries than high-income areas
Read 8 tweets

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