It's important to understand that this wave is going to be different from previous waves in many ways. Every wave so far in the UK, the govt has acted late- when the NHS was already quite overwhelmed. This time doing this will be far far more dangerous- here's why. Thread
We know that there is a lag between cases & hospitalisations rising. This means that even if we act to curb spread today, hospitalisations and deaths will continue to rise for 2-3 weeks because those who will be hospitalised and die in the next 2-3 wks have already been infected.
So every time the govt has taken action, with the NHS severely strained, the situation has continued to get worse for 2-3 weeks in terms of hospitalisations and deaths before getting better. Which means strain on the NHS continues to rise for a period even after we act.
Somehow the NHS managed despite massive pressures (at huge cost to many HCWs), and thankfully we haven't seen the sort of O2 shortages, and large numbers of people dying due to lack of ventilators like some other countries did despite late action by govt.
his time the situation is different, and I'm not sure the govt understands this. The rate of rise with omicron is vastly different from any variant we've seen before- a doubling time of <2 days.
No one knows how long this doubling is sustainable, but this means that by the time we see the impact of cases today in terms of hospitalisations and deaths, several doubling times would've likely passed.
this means by the time hospitalisation rises are felt and acted upon, during the 2-3 wk lag, cases may be several fold higher (no one can actually predict this currently because we've never been here before).
This means once again that hosp will continue to rise after we act, but the rise may be far greater and steeper than anything we've seen before, and NHS utilisation will increase much more steeply even after we act than we've seen ever before due to delay.
The recent SPI-M-O report also makes this clear- if you're acting by the time the NHS is already overwhelmed, it's going to be far far too late.
Yes, boosters will almost certainly help, but everything is telling us that early action is even more important when the rate of spread is so high. Any underreaction or late reaction has the potential for severe damage to public health and the NHS. Much more than before.
I think govt may think they got away with late action before (with huge costs to public health) so they can act late once again, but things are very different this time round, and they need to be aware that the costs of acting late this time will be far more devastating.
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I really thought that perhaps omicron would wake people up to the fact that 'living with' this virus isn't really going to be possible - unless we accept mass death & suffering, and develop an understanding that we need globally coordinated progressive suppression. 🧵
But for many people including scientists omicron has actually strengthened the idea of 'living with it' and dropping all mitigations. This is an extremely privileged take, & completely ignores that the impacts of such policy would be devastating on the most disadvantaged.
So unless you're willing to spell out the consequences of your plans clearly and honestly (mass death, especially among the poor, disabled, vulnerable, elderly, ethnic minorities), and own that this is what you're advocating for society to accept, please don't recommend it.
I've seen people use 'uncertainty' around aspects of evidence to justify inaction. Uncertainty in evidence *does not* mean uncertainty in policy. As I've said, while there's a lot of uncertainty around the exact impact of omicron, there's little doubt that it'll be severe🧵
Same with long COVID. The greater the uncertainty, the more the need for caution, and the more the need for early action. Even the best-case scenarios look very concerning with omicron. So please don't use uncertainty as an excuse for inaction. Inaction will kill in a pandemic.
Best to act early, quickly & scale back if the response was an overreaction. I can safely say that I've not seen any overreaction in UK pandemic policy though, so this is extremely unlikely. Under reaction which is far more damaging has been the mainstay, and continues to be.
There's absolutely no doubt that deaths have risen in Tshwane with lags despite all the 'mild' rhetoric & are likely to increase further as impact is felt from the rapid growth several wks ago. Data from Denmark suggests equivalent or higher hospitalisation rates to delta.🧵
And remember that for SA the 3rd & 4th wave were very different in many respects- a large section of the population was exposed in the 3rd wave, and it's estimated that 70-80% of people may have had previous exposure by the end - so v. different levels of pop immunity.
Given the relatively high levels of vaccination the UK had going into the delta wave, the level of background immunity will be different between the 3rd & current wave, but perhaps not as different as in SA - so we may not see the same difference in severity.
I do think this is a possibility, although hard to know at this point. The lower proportion of omicron in children in the recent Denmark report may point to this, but it's early days so very hard to say. 🧵
Essentially, as explained very well here, delta and omicron could have relative advantages in different settings- delta may be more transmissible, but less escape, so spreads in unvax/unexposed while omicron spreads in vax/exposed groups.
The bit we don't know is relative transmissibility (R0) in a susceptible population. We know omicron has a considerable advantage from escape, but whether it's more transmissible than delta in a fully susceptible population is still unclear.
This is ridiculous- these purifiers cost 6x higher than regular ones that are far more extensively used across the globe. It's completely scandalous. For the amount being paid to Dyson (!), they could be making 6x the number of classrooms safer than they are. Why aren't they?
Here's as device with literally the same CADR as the Dyson one, at a tenth of the cost!! amazon.co.uk/dp/B09HYV7W6B/…
What really angers me is that enriching their friends and cronies is so important to them, that they're very happy to throw the health and lives of children and families out the window, when they could easily be protecting them with standard products everyone is using.
There is no evidence (despite all the rhetoric in the media) that omicron is intrinsically 'milder' than previous variants. Hospitalisation rate in Denmark comparable with delta at equivalent levels of vaccination. And the rapid spread makes it *much* worse.
Any differences in severity of admissions between 3rd and 4th wave in SA may be attributable to some level of protection from vaccination or previous infection - that *does not* in any way mean that the impact of the variant in places it is spreading will not be severe.
The impact will largely be governed by rate of spread rather than severity - and even if it was half or even quarter as severe as delta (no evidence of this), the impact because of rapidity of spread will be massive in most places.