📍SUSPENDING Monoclonal Antibody Drugs—as of today, New York City’s major @MountSinaiNYC hospital system has now formally stopped offering 2 key MAB drugs against #Omicron due to lack of effects in new studies. ➡️What happens when we let #COVID19 run rampant. HT @dianaberrent
2) I share @dianaberrent’s concern that this is a huge reset on pandemic control given how many people in many states rely on this against COVID — especially among many who are vaccine hesitant. MABs are often touted by R governors as an alternative to vaccines.
4) I’m generally not a huge fan of MABs long term — they did work, but expensive, slow to produce (read: rich countries only)c invasive requiring IV infusion, & easily evaded by variants because they are a “monoclonal” one-hit-wonder synthetic antibody. reuters.com/business/healt…
5) Wanna know something that doesn’t care about #Omicron but works against all COVID? Masks and better indoor air quality via ventilation and air disinfection — it’s a NEAT COOL TRICK called aerosol science! See thread 🧵 below 👇
NEW—scientists at Walter Reed Army Institute of Research will soon announce that they have developed a vaccine that protects people from COVID-19 and all its variants, even #Omicron, called The ‘Spike Ferritin Nanoparticle COVID-19 vaccine’, or SpFN. 🧵 defenseone.com/technology/202…
2) The achievement is the result of almost two years of work. The lab received its first DNA sequencing of the COVID-19 virus in early 2020. Very early on, Walter Reed decided to focus on making a vaccine that would work against all of its potential variants.
3) Unlike existing vaccines, Walter Reed’s SpFN uses a soccer ball-shaped protein with 24 faces for its vaccine, which allows scientists to attach the spikes of multiple coronavirus strains on different faces of the protein. 👀
📝A note—Many say racist things to me—& some folks don’t like I share precautionary/doom-y COVID data. Some call me a CCP spy, pharma shill, attention seeking personal brand builder… But I’m none of those. Who I really am:🧵
2) I have no publicist, and unlike many “Twitter docs” during the pandemic, I have never paid for one. I have no website, merch store, or YouTube. I only recently started a mini substack—but I barely use it—& I plan to donate any incidental amount I get from it to COVID research.
3) When I tweet—what I think of is all the lives we could save. All the hospitalization suffering. All the PTSD endured by overworked doctors & nurses. All the long COVID sufferers. Sometimes I’m a misunderstood scientist—but that’s okay if it saves lives in a pandemic.
BREAKING—First #Omicron US death in Texas—in an unvaccinated man **reinfected** after previously having #COVID19. New convalescent blood🩸 studies of survivors (of Alpha, Beta, or Delta variants) show little to no neutralization defense against Omicron. Please #Vaccinate& Boost🧵
2) We do not believe Omicron overall is that much milder if at all than Delta. Keep in mind that Delta is 2-4x more severe than original Wuhan 1.0 strain. A UK 🇬🇧 study found severity is not significantly lower in terms of % needing hospitalization.
3) Show us the study of almost zero neutralization against #Omicron after previously surviving infections of Alpha, Beta, and Delta? Here you go. Full study linked below.
📍JUST IN—the extremely contagious Omicron variant is now the dominant version of new coronavirus cases in the United States. #Omicron now accounts for 73% of new cases, according to CDC. Just 2 weeks ago? …1%. A weeks ago? 13%. Worried about Christmas 🎄 nytimes.com/live/2021/12/2…
2) Don’t be like UK… this is what is now happening to children 0-5 in 🇬🇧 — all time record hospitalizations and surging 39% in one week 👇
3) in contrast to Omicron’s 2 week rampage from 1% to 73% dominance ➡️ it took Delta over 7 weeks to go from 1% to just 54%. This is why many estimate Omicron to be 3-6x more transmissible. (Repost, sorry for earlier typo)
⚠️FALSE NEGATIVES—The FDA has identified **3** COVID-19 molecular tests that are not able to detect the #Omicron variant & warned that diagnostics from 📌Applied DNA Sciences, 📌Meridian Bioscience & 📌Tide Laboratories will return false negative results. medtechdive.com/news/fda-updat…
2) FDA noted on its website that Tide's DTPM COVID-19 RT-PCR test is currently being performed in the U.S. by more than 30 laboratories, providing the names and cities where the labs are located, but added that the diagnostic "is not believed to be used for high volume testing."
3) In the case of Meridian Bioscience's Revogene SARS-CoV-2 test, FDA said that the company has not yet distributed the diagnostic and does not intend to do so inside or outside the U.S. until the issue is resolved.
📍HIGHER HOSPITALIZATION & DEATHS VS FIRST WAVE—Comparing #Omicron in South Africa🇿🇦 epicenter versus its first wave in 2020 (~Wuhan 1.0 strain), we see Omicron has higher hospitalizations, similar ICU rate, and higher #COVID19 deaths than the 1st wave. 🧵 ceri.africa/publications/