Game plan updated:

I don't think I have changed anything this week. I came close today to nibbling one of my stocks that got hit today for no reason, but waited. I have no plans of selling anything this year as my taxes are closed out for 2021.
All * mean my top 3 the extras are subject to trading sale later. I bought a ton of extra companies down here so I have more to sell for profits on the way back up.

My cash is at 25.95% My lowest cash position since the Spring of 2020.
AI Based Drug Development:

$SDGR 3.53% *
$RLAY 2.82%
$RXRX 2.12% *
$EXAI 2.12% *
Targeted Therapies:

$BPMC 3.53%
$MRTX 3.53% *
$RVMD 2.82% *
$ERAS 3.53% *
Protein Degraders:

$ARVN 2.82%
$KYMR 3.53% *
$CCCC 3.53% *
$GLUE 3.53% *
Cell Therapies:

$FATE 2.82% *
$SANA 2.82% *
$IPSC 3.53% *
$CRBU 3.53%
Synthetic Biology:

$DNA 2.12% *
$TWST 2.82% *
$AMRS 2.82%
$CDXS 2.12%
$BLI 2.12% *
Genomics:

$BEAM 3.48% *
$NTLA 1.41% *
$CRSP 1.41%
$PACB 2.82%
$NVTA 2.82% *

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More from @Biotech2k1

24 Dec
Taking a look at the use of Tech in Biotech.

Here we will look at the use of Automation, Artificial Intelligence and Machine Learning in the Discovery of new drugs.
1/ Introduction:

It can take up to 10 years to develop a new drug. A majority of that time is spent in the lab testing targets and ideas. Its the process of sorting through thousands of potential targets to find the one that is worth advancing.
2/ It can cost a ton of money to develop a drug. The statistics show that it can cost upward of $2.5 billion to bring a new drug all the way to commercial. The high level of failure and high costs of testing and discovery is one space where technology can really help.
Read 25 tweets
23 Dec
Everyone has to develop their own style. You have to go with what works for you. No one person's style is right for everyone. Different people can have different styles that work.
I would never criticize anyone for using a different style from me. Just because mine is different from your doesn't make it wrong. I just use a different style.
I buy into my stock each 10% to 15% they pull back. Then I fade them on the way back up each 20% they run. For the index, I use 10% as its not as big of a mover as many individual stocks. I always keep a minimum position as a core investment.
Read 5 tweets
23 Dec
Taking a Look at $BLI

The stock has been knocked down 80% from its highs off of the short reports. I did my own research, and I don't find any credibility to those claims by the shorts.
1/ The company looks cheaply valued at only $1.3 billion market cap with over $123 million in projected 2022 revenues and $197 cash on the books.
2/ Berkley Lights makes machines that automate and simply the lab process. They have 3 machines with the Beacon, the Lighting and the Culture Station. The main machine is the Beacon which uses chip built with thousands of pens.
Read 13 tweets
22 Dec
My 2 overweight themes:

I have 2 themes that are overweight. I had a few names in there I was debating. I finally made my decisions on the synthetic biology and genomics spaces for the companies that would go.
For synthetic biology, I think it has to be $CDXS. Its an enzyme company that has a role in synbio, but its not as much play on this space as the other names. I am not sure how big the revenues are for enzymes. It might be a small business.
I would keep $DNA, $TWST, $BLI and $AMRS. I set my bid to sell all my $CDXS with a go to complete order at a price I would be happy with. I don't think there is a rush. I would even add some if it really sold off from here.
Read 7 tweets
22 Dec
My Ultimate Chemistry Playlist:

I was going to do a Bio Chem course for SynBio. It seemed right to go along with my Mastery of Genetics, Immunology and Oncology. That is when I realized my chem and organic chem was rusty. Here is my list.
1/ This is the basics to get you started.

youtube.com/playlist?list=…
2/ Then there are 3 Chem classes. Chem 1A
youtube.com/playlist?list=…
Read 11 tweets
22 Dec
How to make the most out of any index.

I have always been a stock picker. I have always valued my skills at picking the best companies out of a long list of companies. I am going to show you how I do it.
1/ If you take any index, a good investor can go over the companies in that index and pick out the top 10 or so that are the best. If you don't have the time, then holding an index is great. If you do have the time, you can outperform any index by picking the best of the best.
2/ I am going to use the $ARKG since its the most popular biotech fund. I love and respect these folks who run this fund. I think they are great people. I also think I could go over their 50 or so holdings and extract the top 10 that I think will outperform over the next decade.
Read 11 tweets

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