Thread by @calyxlaw

New psychedelic inventions?

⁂ Phil Wolfson/KRF—ketamine for postpartum symptoms

⁂ Psilo Scientific—psychoactive & psychedelic fungus extraction

⁂ Cognigenics—5-HT2A “cognitive upgrade”

⁂ Liechti—MDMA response prediction

⁂ Small Pharma—DMT-type compound synthesis

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…and more new psychedelic inventions?

⁂ Ixtlan—psilocybin for Alzheimer’s

⁂ Spirify—hydroxynorketamine analogs

⁂ Guangzhou Dazhou Biomedicine—transdermal ketamine

⁂ Disruption Labs—nanoparticle compositions

⁂ Daniel Lilly—“medicinal food products” with psilocybin

2/14

Ketamine Research Foundation (KRF)—“Ketamine for the Treatment of Postpartum Symptoms & Disorder”

First inventor Phil Wolfson

“treatment of all forms of emotional and psychological symptoms and disorders related to childbirth and its aftermath”

patentscope.wipo.int/search/en/deta…

3/14

Psilo Scientific:

🍄 “Extraction of Psychoactive Compounds from Psychedelic Fungus”

patentscope.wipo.int/search/en/deta…

🍄 “Methanol-Based Extraction of Psychoactive Compounds from Fungus”

patentscope.wipo.int/search/en/deta…

4/14

Psilo Scientific:

🍄 “Compositions Comprising Psychoactive Compounds From Psychoactive Organisms”

patentscope.wipo.int/search/en/deta…

🍄 “Methods & Compositions Comprising Psychoactive Compounds From Psychoactive Organisms”

1: appft.uspto.gov/netacgi/nph-Pa…

2: appft.uspto.gov/netacgi/nph-Pa…

5/14

Cognigenics—“Methods for Sustainable Human Cognitive Enhancement”

Using gene-editing “to lower the population of 5-HT2A receptors in the brain”

“temporary or permanent cognitive enhancement” that delivers a “persistent higher states of awareness”

appft.uspto.gov/netacgi/nph-Pa…

6/14

Liechti—“MDMA Response Prediction”

Dosing MDMA, MDA, MDEA, MDAI, mephedrone, methylene, & 3-MMC

Based on “patient characteristics” to produce “maximum positive subjective acute effects”

Sister PCT of published US app

No claims found inventive

patentscope.wipo.int/search/en/deta…

7/14

https://twitter.com/calyxlaw/status/1471961579579002880

Small Pharma—“Synthesis of N,N-Dimethyltryptamine-Type Compounds, Methods, & Uses”

“an alternative method for the synthesis of DMT and DMT-type compounds...which avoids the use of problematic oxalyl chloride whilst producing high-purity compounds”

appft.uspto.gov/netacgi/nph-Pa…

8/14

Ixtlan Bioscience—“Psilocybin Treatment of Alzheimer’s Disease & Brain Pathologies”

Ixtlan AD Kit—“unique assembly of tools” to treat “a variety of brain pathologies by microdosing of encapsulated 5HT2A receptor agonists, specifically psilocybin”

prnewswire.com/news-releases/…

9/14

Spirify Pharma—“Hydroxynorketamine Analogues, Compositions Comprising Same & Methods of Use Thereof”

“HNK analogs and uses thereof in the treatment of depression, pain, inflammation, and other clinical indications”

All novel, none inventive

patentscope.wipo.int/search/en/deta…

10/14

Guangzhou Dazhou Biomedicine—“Transdermal Drug Delivery System for Ketamine”

Monolithic transdermal patches with ketamine drug-in-adhesive layer

And their use to treat depression, anxiety, and/or pain

appft.uspto.gov/netacgi/nph-Pa…

11/14

Disruption Labs—“Compositions for Supplementing Products with Therapeutic Agents & Methods of Use Thereof”

Nanoparticle compositions w fungus extract, kratom extract, Kanna extract, or kava extract, & incl psilocybin

All claims novel & inventive

patentscope.wipo.int/search/en/deta…

12/14

Daniel Lilly—“Medicinal Food Products & Method for Producing Said Products”

Cannabis & psilocybin “medicinal-infused food items” w extended shelf life

Cannabis & psilocybin:

🍨 ice cream

🥛 coffee creamer

🥤 drink product

🧀 cheese product

appft.uspto.gov/netacgi/nph-Pa…

13/14

Follow psychedelic patent applications with the @PsilocybinAlpha patent trackers:

psilocybinalpha.com/data

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