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Hannah Davis (ON HIATUS FOR JANUARY) Profile picture
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5 Jan, 4 tweets, 1 min read
Getting an illness that has been unnecessarily politicized is a nightmare.
I don’t want to deal with trolls and harassment for making threads about biomedical papers.
(and obviously there are many politicized illnesses, #LongCovid is just one. but one everyone wants to have an opinion on)
anyway I am reaching my limit. this has been a lot.

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More from @ahandvanish

Hannah Davis (ON HIATUS FOR JANUARY) Profile picture
5 Jan
New, very strong, meta-analysis published on 81 studies estimating #LongCovid prevalence!

Key findings:

32% of patients have fatigue at 12 weeks, 31% at 6+ months
22% have cognitive impairment at 12 weeks, 21% at 6+ months

Lots of additional info:

1/
 sciencedirect.com/science/articl…
It focuses on 2 most common & debilitating #LongCovid symptoms: fatigue & cognitive impairment. Unlike other studies which don't include cognition or only include 1 impairment (i.e. difficulty concentrating), this includes memory & more comprehensive cognitive symptoms.

2/
A really key finding is that fatigue and cognitive impairment were not statistically significantly different between hospitalized and non-hospitalized patients!

This is a major point as the public assumes that non-hospitalized cases are "mild".

#LongCovid

3/
Read 10 tweets
Hannah Davis (ON HIATUS FOR JANUARY) Profile picture
23 Dec 21
This week marks the 1 year anniversary of @patientled's 2nd #LongCovid paper (now peer-reviewed & published: thelancet.com/journals/eclin…).

The good news: it got better information to many new researchers, including the accurate symptoms, neurological severity, & testing issues.
1/
It has over 200k views & several hundred citations, & informed policy in many countries & orgs, including the US, UK, Belgium, Spain, the WHO, CDC, & others.

The bad news:

2/
Most of this info is still not common knowledge to the general public & new patients. So many have no knowledge that cognitive dysfunction, memory issues, neurological issues, post-exertional malaise, dysautonomia (incl temperature & heart issues), & more are SO COMMON.

3/
Read 7 tweets
Hannah Davis (ON HIATUS FOR JANUARY) Profile picture
30 Nov 21
Exciting paper on endothelial dysfunction (ED) in #LongCovid! (Endothelium is a membrane that lines blood vessels).

"Long COVID-19 symptoms, specifically non-respiratory symptoms, are due to persistent endothelial dysfunction."

frontiersin.org/articles/10.33…

Some key points:

1/ Image
-Endothelial dysfunction (ED) is associated with high cholesterol!
-3 symptoms were associated with ED: fatigue, cognitive dysfunction, & shortness of breath. Others, including loss of sense of smell & cough, were not!

#LongCovid

2/ Image
-Reduced Left Ventricle GLS (Global Longitudinal Strain) was associated with #LongCovid (which I believe validates findings from @PutrinoLab et al?)
-There's a note that beta blockers were associated with reduced Long Covid symptoms

3/
Read 6 tweets
Hannah Davis (ON HIATUS FOR JANUARY) Profile picture
29 Nov 21
It might not be obvious to those without kids or those who aren't following COVID data closely, but schools are creating & normalizing some of the worst COVID policies. My friend is a teacher who was exposed to 2 students (both positive) during close in-person tutoring...

1/
But the school doesn't count it as an exposure because they were all masked & she doesn't have symptoms (yet - they take 5-6 days to appear).

They have a substitute teacher shortage (obviously) so she isn't even allowed to self-quarantine; they made her come back to work.

2/
Another school I know of started out saying a class only has to quarantine if 2 kids are positive; that moved up to 4 kids, then half. So if half minus one students in the class test positive, the class doesn't quarantine 🤯

3/
Read 5 tweets
Hannah Davis (ON HIATUS FOR JANUARY) Profile picture
19 Nov 21
I mentioned treatments on this panel today - #LongCovid providers need to learn what is available from existing post-viral illness & myalgic encephalomyelitis experts.

This list of treatments is from the ME/CFS Clinician Coalition & is super useful:

drive.google.com/file/d/1T6psBJ…
The ME/CFS Clinician Coalition is a wealth of resources. Here are a list of courses with Continuing Medical Education (CME) credits for new #LongCovid providers: mecfscliniciancoalition.org/medical-educat…

2/
Here is a recommended list of tests to do for #LongCovid patients if you're a new provider:

drive.google.com/file/d/1Yu79EY…

cc @WesElyMD @kavitapmd

3/
Read 4 tweets
Hannah Davis (ON HIATUS FOR JANUARY) Profile picture
3 Nov 21
It's been a rough week of learning that the Covid info in the general public is way worse than I understood.

I didn't understand that doctors are *still* telling people they're 100% safe from transmission/transmitting if they're vaccinated, even if they're 8 months out from vax.
I didn't understand that people are sending their kids to school despite someone in the house having Covid.

I didn't understand the cognitive games & justifications people were using to go out with friends even if their partner is ill.
I've reached a new level of hopelessness I didn't think was possible. The amount of information that needed to be communicated to the public like 4 months ago is just not happening, and people are taking advantage of that to be selfish.
Read 4 tweets

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