Thread by @eozdalga

In the last 8 days, I have been reviewing the charts of every #covid+ patient hospitalized at #Stanford Hospital. Here are my observations... @StanfordHealth 1/x

While we currently are having over 95% of covid positive tests (both inpatient and outpatient) come back #omicron, much of our critically ill is still driven by #delta. 2/x

This is due to delta causing more severe disease (and hence hospitalizations) and reflecting delta patients who have been in the hospital prior to the omicron surge. 3/x

In fact, almost every patient with omicron that has been admitted to the hospital and requiring oxygen support usually has an additional medical condition contributing to the need for oxygen. And a majority require minimal oxygen (e.g. nasal canula 1-2 liters). 4/x

Radiographic findings in CT scans and chest x-rays are much more likely to show pneumonia with delta keeping with the multiple studies showing that omicron is less likely to travel past the airways into the lung. 5/x

We are not yet seeing a plateau of total covid hospital admissions. However the number of patients in critical care from covid has been stable, similarly reported in other institutions. 6/x

Of our hospitalized patients, approximately 35% of cases are not hospitalized for covid. Many are asymptomatic and some mild to moderately symptomatic from covid. 7/x

Many are hospitalized due chronic disease (e.g. cancer patients on chemo) to get remdesivir and be observed but otherwise stable. Once we have oral antivirals and better access to monoclonals, the percentage of patients hospitalized for this reason will improve. 8/x

And of course, we're still seeing a huge benefit from #vaccinations. Much of our critically ill are not just delta but also unvaccinated. Many are also chronically immunosuppressed. 9/x

Special thank you to @benjamin_pinsky who runs our lab and getting the variant data. Thank you @Neera_Ahuja and @WillCollMD! @StanfordDeptMed