1/ Did you know that you can use your genetic raw data file from #23andMe or #AncestryDNA to learn more about your health?

A thread on using your data to optimize health and prevent chronic disease 🧵
2/ When getting started learning about how your #genes impact susceptibility to chronic disease, it can be overwhelming.

It isn't like high school science when you learned you inherited the 'brown eye gene' or the 'short gene'.
3/ Most chronic diseases, like #diabetes or #heart disease, have a genetic component. But it is a combination of multiple genetic variants along with lifestyle factors that lead to disease.
4/ Why even bother with understanding your genetic risk? It just makes sense to focus on the lifestyle and wellness changes that will actually make an impact for you. So much advice from 'health gurus' is generic, applying to the majority, but not to you as an individual.
5/ Where to start? Check the Top 10 genes that will make a major impact.
geneticlifehacks.com/top-10-genes-t…. .

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More from @GeneticLifehack

Dec 21, 2021
1/ Columbia University researcher on estimated vaccine-related deaths in the US. The average vaccine-induced fatality rate is estimated at 0.04%. (Holy cow!! That's higher than the IFR for most people. )

Full study (preprint)
researchgate.net/publication/35…
2/ "Vaccination correlated negatively with mortality 6-20 weeks post-injection, while vaccination predicted all-cause mortality 0-5 weeks post-injection in almost all age groups and with an age-related temporal pattern consistent with the US vaccine rollout."
3/ "Results from fitted regression slopes (p<0.05 FDR corrected) suggest a US national average VFR of 0.04% " ... " and 146K to 187K vaccine-associated US deaths between February and August, 2021"
Read 6 tweets
Sep 13, 2021
CDC has now released data from 13 jurisdictions showing the difference in cases, hospitalizations and deaths for people who are fully vaccinated (14 days after the second jab) with the delta variant. cdc.gov/mmwr/volumes/7…

It leaves me scratching my head, wondering...
I've combined the table header with the data so that it is easier to read.
For these 13 jurisdictions (some are full states, some are large metro areas like NYC), below is the data from June 20 - July 17th.

Here's what I don't understand:
I don't see anywhere the percentage of people fully vaccinated vs. not vacc.

85% of cases are in unvaccinated, age 18-49 -
in these states, at this time.

But... what if 85% of people in that area & age group weren't vaccinated?
The vacc. and unvacc. would have the same risk.
Read 5 tweets
Aug 26, 2021
Study from the University of Waterloo, Fluid Mechanics Research Lab:
"The study showed that most common masks, primarily due to problems with fit, filter about 10 per cent of exhaled aerosol droplets. The remaining aerosols are redirected, mostly out the top of the mask where...
...it fits over the nose, and escape into the ambient air unfiltered.

By contrast, higher-quality, more expensive N95 and KN95 masks filtered more than 50 per cent of the exhaled aerosols that can accumulate indoors and spread the COVID-19 virus when inhaled by other people."
uwaterloo.ca/news/media/stu…

The results surprised me...Not in the surgical mask results (I know they're fairly useless), but that N95 aren't all that effective.

The article goes on to conclude the one (very obvious) thing that no one seems to pay any attention to:
Read 4 tweets
Aug 15, 2021
1/4 Study out of Wisconsin showing that vaccinated and unvaccinated people who test positive for SARS-CoV-2 have same viral load. PCR threshold (Ct) shows high viral load in both vaccinated and unvaccinated alike.

medrxiv.org/content/10.110…
2/4. "we show that individuals in Wisconsin, USA had similar viral loads in nasal swabs, irrespective of vaccine status, during a time of high and increasing prevalence of the Delta variant. Infectious SARS-CoV-2 was isolated from 51 of 55 specimens (93%) with Ct <25 from .."
both vaccinated and unvaccinated persons, indicating that most individuals with Ct values in this range (Wilson 95% CI 83%-97%) shed infectious virus regardless of vaccine status. Notably, 68% of individuals infected despite vaccination tested positive with Ct <25, including ...
Read 4 tweets

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