💉 Today marks exactly 100 years since Leonard Thompson, a 14-year-old boy dying from type 1 diabetes, became the first person to receive an injection of insulin on 11 January 1922.
A thread 👇 (1/6)
⬇️ Within 24 hours, Leonard’s dangerously high blood sugar levels dropped, but he developed an abscess at the site of the injection and still had high levels of ketones. (2/6)
🔬 Scientists worked day and night on purifying the extract even further, and Leonard was given a second injection on 23 January 1922. This time it was a complete success and Leonard’s blood sugar levels become near-normal, with no obvious side effects. (3/6)
🙌 For the first time in history, type 1 diabetes was not a death sentence. (4/6)
Insulin saved Leonard’s life and countless others over the last century. It’s so exciting to see how far diabetes research has come since then, but there's still a way to go until we find a cure. We're determined to get there - because diabetes is relentless, but so are we. (5/6)
🔬 Today, we have one final #LabToLife story lined up for you as we get ready for #WorldDiabetesDay tomorrow!
Today we’re hearing from Beth Williams, a PhD student whose research is looking at how we might be able to prevent kidney disease in people with diabetes… (1/9)
💬 “Diabetes affects so many people worldwide, and I was fascinated by the fact that one condition can lead to such a variety of secondary complications – the treatments for which, are very limited.” (2/9)
“I knew the importance of research in improving this, which inspired me to pursue a PhD in diabetic kidney disease.” (3/9)
It's that time of week again, and today's #ResearchFriday is all about zombie cells... 🧟 (1/6)
Cells in our immune systems, called T cells, help us fight infections and heal wounds.
As we get older, T cells can sometimes go wrong and become zombie-like. They don't die as cells naturally should and they turn other cells into 'zombies' too. (2/6)
🔬 Dr Sian Henson found that people with #Type2 diabetes have more zombie T cells than people without diabetes. It means wounds don’t heal as quickly and they could make you more prone to infections. (3/6)
1/4 On 7th November 1920 – exactly 100 years ago – a Canadian surgeon, Frederick Banting, paid a visit to scientist John Macleod in a meeting that would lead to one of the greatest ever medical breakthroughs.
2/4 Banting wanted help to figure out how to remove insulin from a pancreas, so that it could be used to treat diabetes.
3/4 Together, they began to plan a series of experiments that led to the discovery of insulin and would save the lives of millions of people with diabetes over the next century. Their work continues to change lives and inspires our ongoing commitment to research.
(1/6) Lots of you have been asking whether you need to follow the shielding advice from the government. Here are the facts on shielding, and what it means for people with #diabetes.
(2/6) Shielding means staying at home and avoiding all face-to-face contact for at least 12 weeks. It’s a way of protecting extremely vulnerable people who are at a very high risk of severe illness from coronavirus.
(3/6) Who is classed as extremely vulnerable? At the moment, these are people with certain types of cancers and severe respiratory conditions. You can find the full list of people who should be shielding on the government website.