Thread by @clearyb1

Love this paper. Majorly jealous of the Scottish Health Informatics/Research infrastructure that enables this. A 🧵on #MedsInPregnancy TL;DR- get the vaccine, protect yourself, protect your baby. Ignore other messaging- they’re either misinformed or trying to sell you something

https://twitter.com/per_damkier/status/1482046707428954113

To place COVID vaccines in context, we now have more pregnancy outcome data for them than for a lot of other commonly used medicines. This study adds data on over 18,000 pregnancies to a constantly evolving evidence base.

Vaccine coverage in pregnancy is disappointing with less half the level of vaccine uptake in pregnancy compared with the general female population 18-44yrs: 32.3% vs. 77.4%

As usual there are sociodemographic determinants of vaccine uptake with the most deprived having less than half the level of uptake of the least deprived quintile.

The vast majority of the burden of infections, hospital admissions and critical care admissions is borne by the unvaccinated.

The likelihood of the baby being stillborn or dying in the first 4 weeks of life is raised to a worrying extent if there has been a COVID infection within 28 days of birth. Compare the absolute risk for those who get COVID and those who are vaccinated:

The likelihood of preterm birth is also significantly raised by COVID within 28 days of birth. Those who have any COVID vaccination have the same rate as the background population.

COVID is causing devastating PREVENTABLE adverse pregnancy outcomes. The absolute risk of stillbirth or death in the first 4 wks is greater than that from poorly controlled diabetes or smoking above 40 cigarettes per day ncbi.nlm.nih.gov/pmc/articles/P…

Health professionals- please play your part in informing and supporting women in this decision making process. Messaging should be clear- there is considerable risk of avoidable harm without the vaccine. #BoostTheBump #VaccinesSaveLives

Well done to @sarahjestock Rachel Wood @DrAzizSheikh & colleagues. 👏👏👏👏👏