Furin cleavage site data and discussion included. Identical sequence stretch on S. cerevisiae chromosome XIII identified and suggested as potential recombination donor for the furin site insert in the SARS-CoV-2 spike glycoprotein
3. Revised version 3 includes new data regarding the origin of the unusual FCS in SARS-CoV-2. Indeed, with these new data & evidence, it suggests that this critical site is the product of a recombination event after synthetic passage in genetically manipulated S. cerevisiae cells
4. . Overall, the research presented in this article now provides strong evidence that SARS-CoV-2 has an origin in synthetic yeast, and as such is not a product of natural evolution alone.
5. Highlighted Revisions - 1
"At this junction, we detect a highly specific stretch of yeast DNA encoding for the critical furin cleavage site insert PRRA, which has not been seen in other lineage b betacoronaviruses"
6. Highlighted Revisions - 2
"Our data specifically allow the identification of
the yeast S. cerevisiae as a potential recombination donor for the critical furin cleavage site in SARS-CoV-2"
7. Highlighted Revisions - 3
"Of special interest in this analysis was a 16 base sequence TTCTCCTCGGCGGGCA near P2 between position 23599 & 23614, which corresponded to the furin cleavage site & identically aligned with bases [810386..810401] from S. cerevisiae chromosome XIII"
8. Highlighted Revisions - 4
"Yeast (S. cerevisiae) standardized BLAT z-scores representing the relative homology signal from all alignment scores in 13 representative SARS-related coronaviruses"
Note that only, SARS-COV 1, SARS -COV 2 and RaTG13 show Yeast anomalies.
9. Highlighted Revisions - 5
"According to our data, this cleavage site is specifically compatible with a recombination event including chromosome XIII of S. cerevisiae, which shares a unique nucleotide sequence that encodes
the necessary insert PRRA"
10. Any questions?
Corresponding author: Andreas Martin Lisewski
a.lisewski@jacobs-university.de
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1. A Modest Proposal for the Fair Imprisonment of Women and the Liberation of Men
By a Concerned Citizen of Reason,
Published in The Rational Gazette on X
March 24, 2025
2. Dire Injustice!
It is a lamentable truth, oft repeated in the progressive broadsheets and the sanctimonious halls of modern discourse, that the state of our prisons reveals a dire injustice.
3. Gaol'd Wretches
We are told, with furrowed brows and trembling voices, that Black men, comprising a mere 4% of the good people of England and Wales, yet numbering 13% of our gaol’d wretches, suffer under the cruel yoke of systemic discrimination.
@Ticklicker56 @angie_rasmussen @Dissenting2020 @DrStrangeLovett @Rebecca21951651 @All_New_to_This @VaughnMises @R_H_Ebright @Florin_Uncovers @ban_epp_gofroc @MJnanostretch @Muller_Lab @SolidEvidence @ydeigin @ciukzwil @tgof137 @StavaRune @VBruttel @FondueMean @tom335363 @BioSRP @stevenemassey @jbloom_lab @BallouxFrancois @Ayjchan @mattwridley RML expertise in biodefense inlcudes tick & flea agents, so I doubt she would want to discuss how many ticks they have or what they inject them with.
1. Latest Victim of Flo Debarre's "Doxxng" Crusade
Is ME!
I got a disturbing & threatening email, mentioning:
"room for negotiation about the name"
"1st story is often the one that sticks, even if it's not accurate..your chance to negotiate terms"
"continue over Signal"
2. Le Monde
The reporter she is working with, William Audureau @Willvs , seems a principled journalist and did not know of her nefarious doxxing activities against me and other members of DRASTIC and our supporters in Academia, of which he dissaproves.
@Willvs 3. Best way to deal with bullies is to expose them!
I thus emailed CNRS, Cyber Security Office & the Minister of the Interior to complain
"Participant 12" (maybe a soldier at Aldershot). after infection with SC2, over time experienced a substantial number of mutations suggestive of rapid evolution.