Having spoken to many experts and organizations including experts from Costco and @AARP it was clear that even if the intent is there, providing low cost drugs in our system is extraordinarily difficult.
So I'm glad someone is taking the initiative.
The fact that your copay with insurance can be higher than paying out of pocket at the pharmacy tells you how broken the system is, how much the entire supply chain except the patient benefits from the current system.
Even when life saving expensive drugs like imatinib become generic, a low price is not guaranteed.
1) Because to enter formularies the generic is also priced high to accommodate all the rebates that go to middlemen. That why you see this kind of disparity in cost.
Even with @GoodRx coupon the lowest price is $120. Not $17.
And as a patient you wouldn't know that for this drug on this day, there is a much higher price at say Walgreens compared to Walmart.
2) Second is having one or two generics is not enough. Need more than 4 generics to have real completion and impact on prices. Many generics are hesitant to enter the US market if there are already a couple on the market because they would find it hard to enter formularies.
3) Third is Pharma has made it hard for generics to enter the market. And by the time they do, there is already a new and improved brand name version which makes the older one (which still works quite well) appear to seem outdated. We wrote about it here. mayoclinicproceedings.org/article/S0025-…
*competition
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One thing that's clear watching the pandemic for the last 2 years is that the only way to truly contain it was early action. A few countries did it the right way. Saved a lot of lives.
If you didn't do the right thing early on, the task became infinitely harder.
Countries which successfully contained covid early on now face a problem of how long they can realistically sustain their approach.
These countries have vaccinated their public and did all the right things. But Omicron makes it very hard.
Countries which acted late find rising cases the moment preventive measures are relaxed. And whenever a new variant arises. It's disheartening.
It's a medical miracle how vaccines developed within one year against the wild strain of COVID have maintained 90% efficacy against hospitalizations against an onslaught of variants. coronavirus.health.ny.gov/covid-19-break…
Risk reduction is how most of medicine works. Few things in medicine work 100%.
Few things work 90%.
You see the same effect in other places as well. Here is deaths by vaccination status from Switzerland. ourworldindata.org/covid-deaths-b…
As I have indicated the US is so large geographically that the overall time to peak and fall down for the country as a whole will be longer that South Africa or the UK. But each state will likely behave like the east coast states.
Prior Covid also offers protection. But vaccines augment that protection even more.
Omicron may have lesser propensity for lung involvement, but it's not zero. We see people getting seriously ill. We see deaths. It's luck of the draw. The risk is not worth it.
A lot of questions to my recent tweet on South Korea ask how did they do so well?
Its a combination of great talent & leadership, uniform non-politicized messaging, border control, effective test/trace system, high compliance with masks, distancing, & vaccination.
A strategy.
Many replies I got say it best. And I'll highlight some of them.