“Breakthrough” infections DO NOT mean vaccines don’t work. Remember, they are preventatives, NOT cures. One can still contract COVID once vaccinated. As long as that vaccine is preventing you from facing severe disease and worse, it IS working and doing what it was designed to.
The term infection refers to the virus entering and being detectable in your system regardless of whether OR NOT it makes you sick, whereas the term illness refers to the virus entering, being detectable in your system AND making you sick. It it important not to conflate the two.
The first thing to know about the COVID-19 vaccines is that they’re doing exactly what they were designed and authorized to do. Since the vaccines first started their rollout late last year, rates of COVID-19 disease have taken an unprecedented plunge among the immunized.
The second thing to know about the COVID-19 vaccines is that they’re flame retardants, not impenetrable firewalls, when it comes to the coronavirus. Some vaccinated people are still getting infected, and a small subset of these individuals is still getting sick
-and this is completely expected. “Breakthroughs” are known to occur after vaccination against other diseases, such as influenza and measles. Why? Because NO VACCINE IS 100% EFFECTIVE.
“Even the measles vaccine, which is incredibly effective, fails to protect about 3% of vaccinated individuals who are exposed to the virus. Jonas Salk's polio vaccine-hailed a medical miracle- was 80% to 90% effective at preventing paralysis caused by the polio virus.”
So, for those saying the Polio vaccine is sterilizing? Try again. It took a DECADE for Polio to be eliminated in the U.S. and even longer for other parts of the world and guess what? It is still not fully eradicated. It’s still endemic in some countries. pubmed.ncbi.nlm.nih.gov/28718581/
Measles and Polio breakthrough infections aren't just rare because the vaccines are so effective but also because those who are vaccinated rarely interact with infected people. Even with highly effective vaccines for COVID-19, breakthrough infections are likely to keep happening
As @angie_rasmussen says: "Polio is just one example of how vaccines work to reduce R even when they imperfectly prevent infection. What does the data say for Omicron?" I HIGHLY recommend reading this thread AND all the studies within. I’ll link them here.
Breakthrough infections typically cause mild to moderate symptoms, if one develops symptoms at all. Another benefit of vaccines is that they shorten the length of illness for many individuals who do become infected. Vaccination REDUCES disease severity and duration of illness.
A great line from Dr. Rasmussen’s thread: “Vaccines work but not instantly. Polio elimination took years and that was with an extremely pro-vaccine public who couldn’t wait to not get Polio. Just because the vaccines aren’t working on your timetable doesn’t mean they don’t work.”
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Just a heads up. Regarding “Neo-CoV.” IT IS NOT A NEW COVID-19 VARIANT. Please be aware. It’s another type of Coronavirus that was first reported in 2012 and then again in 2015 during the outbreak of MERS-CoV. It has been found in bats and NO HUMAN TRANSMISSION. Don’t get misled.
NeoCov can use ACE2 receptors of bats BUT NOT ACE2 receptors of HUMANS and DOES NOT INFECT HUMANS in its current form. It spreads EXCLUSIVELY among bats.
SHOULD YOU WORRY ABOUT NEOCOV? “No, you should not be worried about the reports of this MERS-linked virus going through a zoonotic effect and transmitting from animals to humans. The last outbreak of MERS was reported in 2015 and the World Health Organization (WHO) said in 2019
So, not COVID-19 related, however, this is really exciting news I wanted to share. The first participant has been dosed in the Phase I study of Moderna's HIV vaccine candidate, mRNA-1644, which uses the same mRNA technology as our COVID-19 vaccines!
Approximately 38 million people worldwide are currently living with HIV with 1.2 million in the U.S. Approximately 2 million new infections of HIV are acquired worldwide every year and approximately 690,000 people die annually due to complications from HIV/AIDS.
mRNA-1644 is a novel approach to HIV vaccine strategy in humans designed to elicit broadly neutralizing HIV-1 antibodies (bNAbs). The Phase 1 study for mRNA-1644 will use iterative testing to validate the approach and antigens and multiple novel antigens will be used
Guys, BA.2 isn’t new. It’s been around since last year. It’s a sub-lineage to BA.1. They’re both still Omicron. It isn’t expected to be any more severe or expected to cause another wave. It might just eventually replace BA.1. End of the day, still Omicron. Let’s not lose focus.
Per @PeacockFlu: BA.2 shares a lot of mutations with BA.1, but it also has some differences. BA.2 also lacks the Spike Δ69-70 mutations. It means it does not cause S gene target failure. Remember the “stealth” version of Omicron? Yeah, that’s BA.2. theguardian.com/world/2021/dec…
Just so I can prove this isn’t necessarily new you can see here. BA.2 appears to be the major Omicron lineage in (part of) India and the Philippines and there is evidence it is growing compared to BA.1 in Denmark, UK, Germany and some other areas.
Wisconsin’s first case of Omicron was detected on December 4th, 2021 and became the dominant variant over Delta within four weeks so Omicron IS included in this analysis.
•dataportal.slh.wisc.edu
•tmj4.com/news/coronavir…