Just a heads up. Regarding “Neo-CoV.” IT IS NOT A NEW COVID-19 VARIANT. Please be aware. It’s another type of Coronavirus that was first reported in 2012 and then again in 2015 during the outbreak of MERS-CoV. It has been found in bats and NO HUMAN TRANSMISSION. Don’t get misled.
NeoCov can use ACE2 receptors of bats BUT NOT ACE2 receptors of HUMANS and DOES NOT INFECT HUMANS in its current form. It spreads EXCLUSIVELY among bats.
SHOULD YOU WORRY ABOUT NEOCOV? “No, you should not be worried about the reports of this MERS-linked virus going through a zoonotic effect and transmitting from animals to humans. The last outbreak of MERS was reported in 2015 and the World Health Organization (WHO) said in 2019
that there has been a reduction in cases of MERS globally. However, as of now, there has been no development to indicate that any MERS-CoV-linked virus has spread among humans. There have been NO human infections of NeoCoV globally and there have been NO deaths.”
Why is it in the news? Because of a PRE-PRINT with A LOT of hypotheticals and media outlets running a mile with it. NeoCoV is an actually an old virus closely related to MERS-CoV (as I stated above) which enters cells via DPP4 receptors. What's “new”is that NeoCoV can use ACE2
receptors of bats but NOT human ACE2 receptors in its current form. It would need to undergo mutations to be able to do so that has NOT HAPPENED. So DO NOT buy into these sensationalist headlines please. It is just blatant misinformation at this point.
It is NOT a new SARS-CoV-2 variant like Delta or Omicron. Again, there has been no development to indicate that any MERS-CoV-linked virus has spread among humans. There have been NO human infections of NeoCoV globally and there have been NO deaths.
The WHO, which identifies and notifies mutations and new virus outbreaks, has not said anything about these reports about NeoCoV. indiatoday.in/science/story/…
• • •
Missing some Tweet in this thread? You can try to
force a refresh
So, not COVID-19 related, however, this is really exciting news I wanted to share. The first participant has been dosed in the Phase I study of Moderna's HIV vaccine candidate, mRNA-1644, which uses the same mRNA technology as our COVID-19 vaccines!
Approximately 38 million people worldwide are currently living with HIV with 1.2 million in the U.S. Approximately 2 million new infections of HIV are acquired worldwide every year and approximately 690,000 people die annually due to complications from HIV/AIDS.
mRNA-1644 is a novel approach to HIV vaccine strategy in humans designed to elicit broadly neutralizing HIV-1 antibodies (bNAbs). The Phase 1 study for mRNA-1644 will use iterative testing to validate the approach and antigens and multiple novel antigens will be used
“Breakthrough” infections DO NOT mean vaccines don’t work. Remember, they are preventatives, NOT cures. One can still contract COVID once vaccinated. As long as that vaccine is preventing you from facing severe disease and worse, it IS working and doing what it was designed to.
The term infection refers to the virus entering and being detectable in your system regardless of whether OR NOT it makes you sick, whereas the term illness refers to the virus entering, being detectable in your system AND making you sick. It it important not to conflate the two.
The first thing to know about the COVID-19 vaccines is that they’re doing exactly what they were designed and authorized to do. Since the vaccines first started their rollout late last year, rates of COVID-19 disease have taken an unprecedented plunge among the immunized.
Guys, BA.2 isn’t new. It’s been around since last year. It’s a sub-lineage to BA.1. They’re both still Omicron. It isn’t expected to be any more severe or expected to cause another wave. It might just eventually replace BA.1. End of the day, still Omicron. Let’s not lose focus.
Per @PeacockFlu: BA.2 shares a lot of mutations with BA.1, but it also has some differences. BA.2 also lacks the Spike Δ69-70 mutations. It means it does not cause S gene target failure. Remember the “stealth” version of Omicron? Yeah, that’s BA.2. theguardian.com/world/2021/dec…
Just so I can prove this isn’t necessarily new you can see here. BA.2 appears to be the major Omicron lineage in (part of) India and the Philippines and there is evidence it is growing compared to BA.1 in Denmark, UK, Germany and some other areas.
Wisconsin’s first case of Omicron was detected on December 4th, 2021 and became the dominant variant over Delta within four weeks so Omicron IS included in this analysis.
•dataportal.slh.wisc.edu
•tmj4.com/news/coronavir…