The next CDC Opioid Guideline draft is coming:

Be ready to speak LOUDLY to protect patients who were *not protected* by institutions that gave that the 2016 Guideline regulatory force, without regard to the the complexities of scientific evidence
2/My 2016 comment to CDC anticipated such harm:

“As medical boards, insurers and government agencies enforce this guideline, prescribing differently from the topline recommendations is likely to become onerous, leaving many patients in the lurch”

stefankertesz.medium.com/considering-cd…
3/Many of us didn’t fully anticipate that patients would be abandoned,

Or that DEA would use that threshold to investigate doctors,(and to seek criminal convictions)

But I now have observed that is the reality
4/By 2019, the CDC agreed their Guideline was misapplied.. they came to that understanding partly as a result of countless protests by patients themselces, and efforts by people like @BethDarnall @speakingabtpain @slsatel @AJ_Gordon

cdc.gov/media/releases…
5/The prescription reductions achieved to date began *before the CDC Guideline*, and they accelerated after. We are now at the level of 1993. Image
6/One can suggest that this massive reduction did contribute to a steep fall in misuse of prescription-type opioids by youth. Image
7/However the expected reduction in mortality from drug poisoning did not materialize. It seems more likely than not, to me, that our Rx reduction contributed to the illicit market’s traction.

The overdose toll rose

washingtonpost.com/health/2021/11…
8/The reality is:

*protecting and helping* people, is

-NOT defined by making Rx pills go ⬆️ (as pharma argued up till 2017)

-NOT defined by making Rx pills go ⬇️

We *always* needed to measure the opioid crisis differently

Image
9/There is reason for hope, beginning with the fact that scientific evidence has justified the concerns we expressed,

and that the CDC received thoughtful criticism on a preliminary draft of its Guideline cdc.gov/injury/pdfs/bs…
10/Were it up to me, the coming Guideline would not be about “opioids”, as if those pills are our primary obligation

The Guideline I wish for would be about helping people with long term pain, and (often) difficult challenges & contexts

But that is not where we are.
11/As things stand we must wait for the draft

Then comment with focus on science but also on ethics.

To discount patients “left in the lurch” (as I wrote 5 years ago) was an ethical failure, not a scientific one.

We must make it *unacceptable* to fail in this way again/fin Image

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More from @StefanKertesz

Jan 20
Hey: 👩🏽‍⚕️👨🏽‍⚕️🧑🏼‍⚕️
I'm sick of stories on health care that erase and dumb down the professional roles & responsibilities of clinicians (doctors, nurses, etc) – whether it’s @NYTimes on genetic screening or @DopesickOnHulu on opioids. /1
The public is flooded with stories about health care that show health professionals as, well,
patsies, victims and cogs.
Health professionals need to ask "why we look that way" to them, and push back /2
That’s what got me talking in our latest podcast from @OnHealer.
We reviewed a @NYTimes story of highly marketed prenatal screening tests.
These tests do traumatize moms if results come in without appropriate clinical counseling.
Listen: pod.link/healer/episode… /3
Read 14 tweets
Jan 19
1/*Hope* Short thread/🧵

Reflections shared with me from Dr. Lachlan Forrow this evening

Eric Cassell - "Hope has *nothing* to do with probabilities"
2/"Everything that is done in the world is done by hope."

Martin Luther and Martin Luther King, Jr.
3/Hope is your superpower. Don’t let anybody or anything make you hopeless. Hope is the enemy of injustice,” Stevenson said. “Hope is what will get you to stand up when people tell you to sit down.”

Bryan Stevenson
Read 4 tweets
Dec 27, 2021
1/Briefs were filed for the Supreme Court today, on whether doctors will continue to be criminally convicted under the Controlled Substances Act when Rx’s were offered in good faith.

Our team’s work was cited in the @national_pain amicus whose thread covers the law.

My 🧵:
2/The use of criminal charges and prison as a method of regulating US opioid prescribing is a U.S.-specific phenomenon.

It reflects the legacy of the Harrison Narcotics Tax Act (1914) and the Controlled Substances Act (1971).

It is a choice we made that other countries didn’t
3/as opioid overdoses rose, Department of Justice announced its intention to use “data tools” to drive prosecutions, ie investigate higher prescribers - justice.gov/opa/pr/attorne…
Read 15 tweets
Dec 22, 2021
1/There is one upcoming Supreme Court Case to follow for anyone who cares about criminal prosecutions of doctors for prescriptions of opioid medicine - specifically Rx where intentions were to deliver appropriate medical care: Ruan v. USA supremecourt.gov/docket/docketf…
2/The central question comes down to whether it is a federal crime for a physician to prescribe opioids, in a way where the government’s experts contend it was imprudent or unwise, when that physician intended and reasonably believed they were acting within standard of care
3/Most prosecutions of non-MDs under the Controlled Substance Act require “mens rea” criminal intent.

If I sell you a PlayStation, believing it is a PlayStation, which turns out to have cocaine inside, I can’t be convicted of a criminal violation of CSA. No criminal intent
Read 10 tweets
Dec 20, 2021
1/There is a *reason* that the decline in Veterans experiencing homelessness is that steep.

It reflects the adoption Housing First approaches, as well as could be done, by @DeptVetAffairs

Anyone who wants to see our research on strengths & weaknesses of this work, see 🧵 Image
2/Bear in mind that our work considered Housing First with “eyes open” as I had raised relevant questions as to what it can deliver, most especially where addiction is part of the picture pubmed.ncbi.nlm.nih.gov/19523126/
3/However, on whole and despite the very real challenges that will happen when housing people with serious mental illness and addiction challenge, the data have been reassuring as to potential for success, like this pubmed.ncbi.nlm.nih.gov/21285095/
Read 7 tweets
Dec 10, 2021
1/It is helpful to see a review of the concerns raised by professionals & patients prior to the publication of the 2016 CDC Opioid Prescribing Guideline - take a look. I will add highlights from my 2016 docket submission. Nearly all issues re-emerged in published research
2/My own 2016 submission to CDC’s docket was- as is appropriate- respectful of authorial expertise and good intentions.

But my top line concerns were 4.

1/Inappropriately broad conclusions derived from untestable propositions

stefankertesz.medium.com/considering-cd…
2/ CDC’s Dose-related recommendations prioritized *relative* risk over *absolute* risk, and minimized consideration of interaction of risk and protective factors -

This is different from approaches applied to nearly all other risk evaluations in medicine (eg NSTEMI, A-fib)
Read 8 tweets

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