Prof. Jose-Luis Jimenez Profile picture
Jan 28, 2022 8 tweets 4 min read Read on X
1/ @Nature: "COVID-10: endémico NO significa inofensivo"

"La palabra 'endémica' se ha convertido en una de las peor utilizadas de la pandemia. Y muchas de las suposiciones erróneas fomentan una complacencia fuera de lugar"

Por virólogo @ArisKatzourakis

www-nature-com.translate.goog/articles/d4158…
2/ "Una enfermedad puede ser endémica, generalizada y mortal. La malaria mató a más de 600.000 personas en 2020. 10 M enfermaron de tuberculosis ese mismo año y 1,5 M murieron. Endémico ciertamente no significa que la evolución haya domesticado de alguna manera un patógeno"
3/ Existe una idea errónea generalizada y optimista de que los virus evolucionan con el tiempo para volverse más benignos. Este no es el caso: no existe un resultado evolutivo predestinado para que un virus se vuelva más benigno..."
4/ "...especialmente aquellos, como SARS-CoV-2, en q la mayor parte de la transmisión ocurre antes de q virus cause una enfermedad grave. Alfa y Delta son más virulentos que la cepa de Wuhan. La segunda ola de la pandemia de influenza de 1918 fue mucho más letal que la primera."
5/ "La mejor manera de evitar que surjan más variantes, más peligrosas o más transmisibles es detener la propagación sin restricciones, y eso requiere muchas intervenciones integradas de salud pública, incluida, de manera crucial, la equidad de la vacuna."
6/ "Cuanto más se replique un virus, mayor será la probabilidad de más variantes problemáticas, muy probablemente donde la propagación sea mayor. Alpha se identificó en Reino Unido, Delta en India y Omicron en sur de África, todos lugares donde la propagación era rampante."
7/ "Pensar que la endemicidad es leve e inevitable es más que erróneo, es peligroso: expone a la humanidad a muchos más años de enfermedades, incluidas oleadas impredecibles de brotes."
8/ "Es más productivo considerar cuán mal podrían ponerse las cosas si seguimos dando al virus oportunidades para burlarnos. Entonces podríamos hacer más para asegurarnos de que esto no suceda."

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More from @jljcolorado

May 26
1/ Survey of CO2 indoors during trip

CO2 (above ~400 ppm outdoors) indicates the amount of exhaled air (& virus) trapped in a space

Also per recent scientific results by @ukhadds, CO2 helps SARS-CoV stay infectious in air much longer

@united flight boarding, pretty terrible! Image
2/ This is the trip so far:

-Low outdoors
-Pretty high ~2000 in @RideRTD bus to airport
- ok ~800 at @DENAirport, except restroom ~1500. Not sure why restrooms at this airport are so often poorly ventilated
- Then boarding on @united, ventilation OFF, so huge increase till ON Image
3/ For details of the recent results on how and why CO2 makes SARS-CoV-2 stay infectious much longer in the air, see this recent thread by @ukhadds

Read 9 tweets
May 8
1/ "After four years of fighting about it, @WHO has finally proclaimed that viruses, including the SARS-CoV-2 virus that causes COVID, can be spread through the air"



By @maggiemfoxscientificamerican.com/article/a-figh…
2/ "It took four years to get here because some leaders in public health, medicine and science clung too tightly to precision and semantics"

"One particular moment of shame came on March 28, 2020, when WHO tweeted: “FACT: #COVID19 is NOT airborne.”

3/ "Words matter. When people heard that COVID might spread on surfaces, they wasted time wiping down groceries. People who misunderstood airborne spread needlessly wore masks on outdoor walks and veered off sidewalks to avoid their neighbors."
Read 7 tweets
Apr 18
1/ @WHO has published a report on updated terminology for disease transmission

I've seen some debate about it. My take:

- Terminology itself is ok. Big progress
- But no recommendations of how to protect!

Report:

Press release: who.int/publications/m…
who.int/news/item/18-0…
2/ The report was likely the result of intense pressure on @WHO during the pandemic:

- They denied that #COVIDIsAirborne on March 2020
- They finally accepted it 2 years later

nature.com/articles/d4158…
@WHO 3/ To their credit, @WHO did invite some of their critics to be part of the committee.

What was the terminology before. In medical circles:

- droplet transmission: if it happened in close proximity, or if particles were > 5 microns

- airborne transmission: if it happened far
Read 34 tweets
Mar 28
1/ New paper in @ScienceMagazine: "Mandating Indoor Air Quality for Public Buildings"

Explaining current status of indoor air quality standards (in short: bad or non-existent), the huge health benefits that would arise from them & proposing a path forward
science.org/doi/10.1126/sc…
Image
2/ "People living in urban & industrialized societies, which are expanding globally, spend more than 90% of time indoors, breathing indoor air (IA)."

"Most countries do NOT have legislated indoor air quality (IAQ) performance standards for public spaces"

science.org/doi/10.1126/sc…
3/ "Few building codes address operation, maintenance, and retrofitting, and most do NOT focus on airborne disease transmission."

"We propose that Indoor Air Quality (IAQ) standards be mandatory for public spaces"

science.org/doi/10.1126/sc…
Read 14 tweets
Oct 4, 2023
1/ Checking the ventilation by measuring CO2 as I travel to the #AAAR2023 conference

@RideRTD bus to Denver airport. Bus route had started 3 min before I got in, already 1500 ppm

Typical of these @RideRTD buses, poor ventilation Image
2/ Not getting any better as time passes in the @rideRTD bus to the airport...

7% of the air is being re-breathed, it has already been in someone else lungs when each of us breathe it. Image
@RideRTD 3/ Given the often poor-to-mediocre ventilation in US transportation systems, I wear N95 masks (not KN95, less good)

In this case @3M VFlex, which I tested at 99.99% filtration for myself

It also stays sealed when I talk, doesn't distort my speech (& add to my Spanish accent) Image
Read 14 tweets
Oct 2, 2023
1/ Video de mi presentación sobre "Transmisión de enfermedades por el aire: cómo funciona, por qué se malentendió, y cómo reducirla"

como parte de la presentación del libro de ventilación de @aireamos

2/ Las diapositivas se pueden bajar de este enlace.

(Son de una charla más larga así que tienen más detalles, pero están todas las de la presentación de @Aireamos)

drive.google.com/file/d/1Bs0RRG…
@aireamos 3/ Miguel Ángel Campano @MA_Campano y @Aireamos han sido los motores del libro de ventilación:

Read 4 tweets

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