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Feb 11 • 9 tweets • 5 min read
New special issue of @RSocPublishing #InterfaceFocus on airborne transmission of SARS-CoV-2 royalsocietypublishing.org/toc/rsfs/2022/…

Intro royalsocietypublishing.org/doi/full/10.10… by Tang, Li, Eames, and me summarizes the contents. /1
"Spread of infectious agents through the air in complex spaces" explores effects of buoyancy, turbulence and their influence on how far aerosols travel, also effects of turbulence and stratification on the spread of infectious agents indoors. royalsocietypublishing.org/doi/full/10.10… /2
"COVID-19: the case for aerosol transmission" reviews evidence from respiratory physiology, lab studies, field measurements, outbreak investigations, animal models. /3
"Comparing aerosol number and mass exhalation rates from children and adults during breathing, speaking and singing" reports that older kids and adults produce similar amounts of aerosols, and singing > talking >> breathing. royalsocietypublishing.org/doi/full/10.10… /4
"Outbreak of SARS-CoV-2 at a hospice: terminated after the implementation of enhanced aerosol infection control measures" included opening of windows, universal masking for staff & taking breaks separately, screening for asymptomatic infection. royalsocietypublishing.org/doi/full/10.10… /5
"High attack rate in a Tong Lau house outbreak of COVID-19 with subdivided units in Hong Kong" finds evidence of spread through wastewater drainage pipes, poor ventilation. Attack rate = 25%. royalsocietypublishing.org/doi/full/10.10… /6
"Modelling airborne transmission of SARS-CoV-2 using CARA: risk assessment for enclosed spaces" presents a model to assess potential exposure of airborne SARS-CoV-2 viruses, with emphasis on virological and immunological factors. royalsocietypublishing.org/doi/full/10.10… /7
"An exploration of the political, social, economic and cultural factors affecting how different global regions initially reacted to the COVID-19 pandemic" looks at answers to the questions shown below in different regions: royalsocietypublishing.org/doi/full/10.10… /8
Oops, forgot the link to Tellier's review: royalsocietypublishing.org/doi/full/10.10…

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More from @linseymarr

Linsey Marr Profile picture
Jan 25
Delighted to have collaborated with @MicroLevitator @jfdavies and team to continue our deep dive into understanding mechanisms of virus decay in droplets and aerosols. /1
Levitated aerosols of various model fluids--we did not test any real respiratory fluids--evaporate and become semi-solid at moderate relative humidity (RH), solid at low RH. Diffusion of potential disinfectants would be inhibited, slowing kinetics of decay reactions. /2
We expect kinetics to also be affected by solute concentrations, which increase at lower RH, so a competing effect. elifesciences.org/articles/65902 by @dylanhmorris & co-authors /3
Read 8 tweets
Linsey Marr Profile picture
Jan 3
Some thoughts for the new year:

How do we do public health better in a country with such a strong culture of individualism? /1
The reluctance to promote rapid tests and N95s is due in part to rules for diagnostics and worker protection (@michael_mina). If the boat is sinking, I'll take any life vest I can get. /2
How do we start adapting our buildings for clean air like we did for clean water? It's time for an Indoor Clean Air Act. @kprather88 See science.org/doi/10.1126/sc… /3
Read 4 tweets
Linsey Marr Profile picture
Dec 21, 2021
Our paper (@isjinpan @ajprussin Duggal lab) on SARS-CoV-2 on surfaces and HVAC filters in dorm rooms housing infected students is now published pubs.acs.org/doi/full/10.10… /1
Free preprint
drive.google.com/file/d/1LB0sb-… /2
We found RNA on 71% of HVAC filters, 57% of surface samples (faucet handle, doorknob, floor, etc.), 67% of bathroom vent grilles at 10 to 10,000 gc/swabbed area of ~10x10 cm2. /3
Read 5 tweets
Linsey Marr Profile picture
Nov 18, 2021
@theNASEM webinar on Public Health Lessons for Non-Vaccine Influenza Interventions: Looking Past COVID-19 today at 1 pm nam.edu/event/advancin… Report released yesterday at bit.ly/3kHhZeW /1
The report recommends use of respirators, surgical/procedural masks, and multi-layer woven cloth face masks to reduce transmission of SARS-CoV-2, and states that face shields alone are not effective /2
It highlights the importance of physical distancing, ventilation, & air filtration to remove pathogens from the air, but recognizes that physical barriers are not effective & may actually be harmful /3
Read 4 tweets
Linsey Marr Profile picture
Oct 22, 2021
Tang & I wrote about updating transmission routes to inhalation, spray, and touch, following up on suggestions by Yuguo Li and @Don_Milton. academic.oup.com/cid/advance-ar… /1
"Current infection-control guidelines subscribe to a contact/droplet/airborne paradigm that is based on outdated understanding. Here, we propose to modify and align existing guidelines with a more accurate description of the different transmission routes." /2
"This will improve the effectiveness of control measures as more transmissible variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge." /3
Read 20 tweets
Linsey Marr Profile picture
Oct 21, 2021
Great editorial about "The COVID-19 crisis is almost certainly an indoor air crisis; it is very likely a ventilation crisis." (among other crises) onlinelibrary.wiley.com/doi/full/10.11… by Nazaroff @WBahnfleth @WargockiPawel Zhang /1
"The phenomenon of low risk outdoors and high risk indoors deserves some explanation. This is probably the most important observation in this pandemic. There is a simple explanation: dilution." /2
"For an ideal expired jet from a person breathing at rest, at a distance >1 m, there is >10-fold dilution from surrounding air because of...entrainment. If the surrounding air is totally free from infectious virus, as it is outdoors, the concentration beyond 1 m is very low." /3
Read 8 tweets

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