"The phenomenon of low risk outdoors and high risk indoors deserves some explanation. This is probably the most important observation in this pandemic. There is a simple explanation: dilution." /2
"For an ideal expired jet from a person breathing at rest, at a distance >1 m, there is >10-fold dilution from surrounding air because of...entrainment. If the surrounding air is totally free from infectious virus, as it is outdoors, the concentration beyond 1 m is very low." /3
"In any well-ventilated indoor environment...with an outdoor-air ventilation rate of 10 L/s/person or more, the background concentration in room air is similarly low. This means that...10 L/s/person ventilation is likely to produce a close-range inhalation risk like outdoors." /4
"Thus, in a well-ventilated indoor space, the infection risk is comparably low to risk outdoors....This reasoning supports an important conclusion: that SARS-CoV-2 transmission does not occur everywhere, but mostly indoors in poorly ventilated spaces." /5
"The dominant view in public health toward fearful airborne transmission fails to account for the power of dilution. Sufficient dilution of airborne infectious aerosols is the key to reducing inhalation transmission, both at close range and at room scale." /6
"Is this the right time for an indoor air revolution? For the first time in history, the COVID-19 pandemic has focused the world's attention on the roles of ventilation in disease transmission." /7
Forgot to list the first author: Yuguo Li. He has been prolific on the topic for a long time, and he understands what's happening with droplets and aerosols at close range better than almost anyone. /8
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Tang & I wrote about updating transmission routes to inhalation, spray, and touch, following up on suggestions by Yuguo Li and @Don_Milton. academic.oup.com/cid/advance-ar… /1
"Current infection-control guidelines subscribe to a contact/droplet/airborne paradigm that is based on outdated understanding. Here, we propose to modify and align existing guidelines with a more accurate description of the different transmission routes." /2
"This will improve the effectiveness of control measures as more transmissible variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge." /3
Just as I advocated for mask use when needed, I'm going to join @j_g_allen in advocating for ending mask rules when no longer needed. In my mind, that's after kids 5-11 have a chance to get vaccinated. /1
My 10-yo will get vaccinated as soon as possible, not because I'm particularly worried about her getting Covid-19 but because I'm worried about her *spreading* it. /2
With the normalization of mask wearing in the US, I hope that people will feel comfortable wearing them or not wearing them as it makes sense (not for political reasons). /3
I wrote about applying what we've learned from Covid-19 to the flu. nytimes.com/2021/10/19/opi… Cleaner air (ventilation & filtration) is a "powerful tool for reducing the risk of Covid-19 transmission, & it should be embraced more thoroughly during this pandemic and to reduce flu"/1
We inadvertently squashed the flu last year, probably thanks to our interventions against Covid-19 combined with our pre-existing immunity to flu. @Lakdawala_Lab showed that this factor is a barrier to airborne transmission. journals.plos.org/plospathogens/… /2
@Lakdawala_Lab "I hope that Covid-19 has catalyzed a shift in thinking about the air we breathe. You wouldn’t drink a glass of water full of pathogens, chemicals and dirt. Why should we put up with breathing contaminated air?" /3
Our paper examining the origins of the erroneous 5 μm cutoff for aerosols v. droplets and the 6' rule is now published. One of my fave interdisciplinary collaborations yet, involving rhetoric, history, aerosol science, fluid dynamics. royalsocietypublishing.org/doi/10.1098/rs… /1
With @katierandall@EThomasEwing@jljcolorado Bourouiba. The 5-μm error came from conflation of how droplets/aerosols move through the air with where they deposit in the respiratory tract. The 6' rule came from misinterpretation of studies with bacteria settle plates. /2
These became entrenched through "citogenesis," which I would define as propagation of mis-cited work. /3 xkcd.com/978/
We did some more testing yesterday and updated tinyurl.com/VTkidsmasks with a column dedicated to efficiency as worn. Added results for KF94/KN95s received from @masknerd. Take homes: N95 clearly the best (small 3M Vflex 9105S), KF94/KN95s around 90%, most cloth masks ~60-80%. /1
Based on our testing and some new studies, we moved all cloth masks to the BETTER category and moved surgical + brace or surgical + cloth double masking to the BEST category, which also has KN95/KF94 (small-sized N95s may work for big kids). /3
Our new preprint led by Hawks and Duggal shows infectious virus emitted in air from hamsters (upper right) on days 1-2 but not later, even though RNA still there (lower right). biorxiv.org/content/10.110… /1
We used a condensation particle sampler with & without cyclone. Saw similar amounts of infectious virus, so it's mostly <8 μm.
8-μm particles can float around for at least 13 minutes, and the smaller ones stay in the air for hours. /2
Sampling method does not exclude potential for resuspension from fur and ground, but there was more virus in oral swab & nasal wash than on fur. Either way, though, there's infectious virus in the air. /3