Alina Chan Profile picture
Feb 12 9 tweets 3 min read
I'm proud of VIRAL. @mattwridley & I had to write this book in record time, compiling months of research and fact checking the book multiple times.

Despite great efforts by natural origin proponents, they have failed to point out even a single piece of misinformation in VIRAL.
@mattwridley The largest criticisms have been that VIRAL is too technical for some readers and that it does not conclude whether SARS-CoV-2 / COVID-19 emerged naturally or due to research activities.

We can't do anything about the latter because there is no direct evidence for either origin.
One question that often comes up is how can we investigate now that 2 years has passed? Isn't this a situation where we will never know the #OriginOfCovid?

My answer is no, there are so many approaches of investigation still left unexplored. It's way too early to give up.
The problem is that many of these routes of inquiry, if clearly specified in the book or publicly, will unnecessarily stigmatize numerous individuals and entities. These investigations should be conducted in a way that protects them from being targeted by the public.
I'm more than happy to be consulted for investigations or commissions on #OriginOfCovid, but VIRAL will not be laying out steps (naming individuals or entities) for investigative efforts.

I recently submitted my recommendations on this topic to the UK Parliament STC.
Some other criticisms from pro-natural origin scientists & journalists are that the book does not go deeply enough into mechanisms of recombination in viruses, and that it should answer for pseudoscientific theories that the book does not mention and neither Matt nor I endorse.
For example, one particular straw man that natural origin folks keep banging on is that RaTG13 was somehow transformed into SARS-CoV-2 in the Wuhan lab.

This is a hypothesis I have repeatedly called a straw man or implausible in public.
Probably because there is no misinformation in our book, critics have tried to insert their own misinformation or even propagate their own misinformation in critical reviews of the book.

Another example:
It gives me confidence in the robustness of the book if its worst critics cannot find a single piece of misinformation in it and have to invent their own misinformation or ask us to answer for misinformation spread by other people.

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More from @Ayjchan

Feb 14
This is an archived page of the Wuhan Institute of Virology 野生动物携带病毒病原特色数据库 database backend h/t @C_Small_

It lists the date, # independent IPs, # visitors, page visits, # requests, and downloads (GB). These ground to a halt in Sep 2019.
archive.md/9MNVZ Image
@C_Small_ Interestingly, the database interface page was visited from outside of China as well during this period: Image
Unfortunately, because the database's public interface page has been removed, it's not easy to tell what was originally there.

A public description of the interface had been archived:
archive.fo/jPPkB Image
Read 11 tweets
Feb 13
People on both sides of #OriginOfCovid agree it was risky to experiment with live SARS-like viruses at BSL2 (low biosafety) & virus hunting + manipulation possibly led to COVID.

The key difference is that one side doesn't think the lab has been transparent. The other side does.
This is why one side insists that there should be an inspection of lab records, research documents, databases etc.

Whereas the other side is willing to take it on trust that the Wuhan lab(s) did not have a SARS-CoV-2 precursor in their possession prior to the detected outbreak.
As a scientist, I am incredulous that all of the virus strains and sequences in a top research lab have already been published at any one time.

But some other scientists seem to believe it is possible for all virus strains and sequences in a lab to be in the public domain.
Read 13 tweets
Feb 9
2 early takeaways from this saga:

1. Chinese scientists asked @NIH NCBI database to delete deposited data containing sequences of early versions of SARS-CoV-2 virus.

2. US-based @biorxivpreprint blocked European scientists from posting their analysis of this data as a preprint.
Never thought I'd ask this, but... @biorxivpreprint @cshperspectives

What is bioRxiv's gatekeeping policy when it comes to original analyses? And would you consider a more transparent approach to this gatekeeping by publishing the name of the reviewer and reason for rejection?
@biorxivpreprint @cshperspectives Although bioRxiv is not a peer review service, it still confers a certain level of credibility to the preprints it has screened.

Has the team at bioRxiv considered that now there may be conflicts of interest among its screeners that should be carefully managed?
Read 5 tweets
Feb 8
An oldie but a goodie.
"Particularly sensitive is the mine shaft where the closest relative of the COVID-19 virus.. was discovered after an outbreak in 2012.. Wuhan Institute of Virology and the China CDC both studied bat coronaviruses from this shaft."
apnews.com/article/united…
I don't buy that elite scientists in China - Wuhan Institute of Virology, Chinese CDC director's lab, Beijing Institute of Pathogen Biology - scoured the Mojiang mine repeatedly over years for bat coronaviruses without thinking the miners were likely infected by a 🦇coronavirus.
These top scientists literally sampled the shit out of thousands of bats, rodents and other animals in that mine for years - testing every sample for viruses that might potentially infect humans.

And some people think they did not suspect the miners had been felled by a virus?
Read 13 tweets
Feb 8
What a difference a year can make.

March 2021:
"many virologists also remain unconvinced by the idea that SARS-CoV-2 was engineered"
buzzfeednews.com/article/petera…
May 2021:
"More investigation is still needed to determine the origin of the pandemic. Theories of accidental release from a lab and zoonotic spillover both remain viable. Knowing how COVID-19 emerged is critical..."
science.org/doi/10.1126/sc…
June 2021:
"You can't distinguish between the two origins from just looking at the sequence. So, naturally, you want to know were there people in the virology laboratory in Wuhan who were manipulating viral genetic sequences?"
caltech.edu/about/news/the…
Read 6 tweets
Feb 8
It troubles me that there are emails and documents located here in the USA which can tell us what SARS-like viruses and rare cleavage sites scientists in Wuhan had discovered.

Why are these not being subpoena'ed so that we can end speculation about #OriginOfCovid?
I keep seeing tweets about not being able to investigate the #OriginOfCovid unless the Chinese government lets us. If you think it through, there is so much info, documentation & communications scattered around the world. A lot of it here in the USA. We've known this since 2020.
The numerous scientists, many here in the US and some in other countries, who were part of the DEFUSE proposal just kept mum about their 2018 furin cleavage site insertion pipeline for nearly 2 years until some anonymous person leaked it.
Read 5 tweets

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