A brilliant plenary at #CROI2022 by @mugecevik reviewing the global COVID epidemiology. 🧵for key points: global epidemic patterns mixed, the main difference in outcomes lies in vaccine coverage for > 60 yo; ⬆️ death rate in US and ⬆️ hospitalized during Omicron explained by that
Factors driving transmission include host, virus, environment & structural; SARS-CoV-2 is here to stay; recovery is part of pandemic response; population health cannot be addressed in short term.
Final points made by @mugecevik in her talk: people are not the drivers of transmission, it’s their unmet needs; we need a systems approach in pandemic response & evidence synthesis is crucial for policymaking. Finally, thanks Muge for allowing me to share your slides!

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More from @CarlosdelRio7

Dec 23, 2021
In the last 72 hrs my phone has exploded with calls/texts/emails of people who have tested positive and are asking for advice. Thus I put together a 🧵with answers:
1. If I have symptoms and my RT is neg do I don't have COVID? Maybe or maybe not. Get a 2nd test 24 hrs later.
2. Can I gather with family for Christmas? Yes but everyone vaccinated (ideally boosted), without symptoms and a negative RT the day before and right before the gathering (double negative RT).
3. Where can I get a RT? In Atlanta Viral Solutions for sure.
4. Can I go to Church Christmas eve/day? Yes but no singing (congregational signing is very high risk), fully masked with a high quality mask and a large room not packed with a short service.
5. Should I cancel a flight? It is safe to fly, wear a high quality mask and keep it on
Read 5 tweets
May 31, 2020
Today marks 5 months from the date China notified @WHO of an outbreaks of atypical pneumonia in Wuhan. Since then 6.2 M cases and > 300K deaths have been notified from 213 countries (US 1.8 M cases and 105K deaths). We have learned a lot about #COVID19 since then:
Transmission: this is a respiratory infection with most transmission occurring from close contact "person-to-person" through respiratory droplets when the person talks or coughs. Is 6 ft distance enough to prevent transmission? Probably not which is why masks are recommended.
Transmission through contaminated surfaces where a person touches and then touches their mouth, nose or eyes is possible. How long viable virus remains on surfaces depends on the type of surface,, the temperature and humidity. Cleaning and hand hygiene important for prevention.
Read 7 tweets
Mar 12, 2020
A few thoughts after hearing Trump: at this point, we are past containment. Containment is basically futile. Containment efforts won’t reduce the number who get infected in the US.
Now we’re just trying to slow the spread, help healthcare providers deal with the demand peak.
Social distancing is critical now to "flatten the curve", to lower the peak of the surge of demand that will hit healthcare providers. And to buy time, in hopes a drug can be developed.
How many in the community already have the virus? No one knows.
We are in mitigation now.
We are currently where at where Italy was a week ago. 40-70% of US population will be infected over the next 12-18 months. After that level we will start to get herd immunity. Unlike flu this is entirely novel to humans, so there is no latent immunity in the global population.
Read 5 tweets

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