🐍 #SnakeBites are a severe issue in India, with 46,000 deaths annually. The country reports more snake bites than any other region, including SA & Africa. I recently had an opportunity to talk about it.
👇👇Sharing some thoughts on snake envenomation and its effects on the kidneys
🐍 WHO did acknowledge that snakebites aren't a disease but "an injury" but
the "envenoming" — the injection of the snake's venom — can be considered a disease.
Both acute and chronic morbidity are REALY high☠️
Amongst the venomous snakes exist the infamous ‘Big Four’ — Indian Spectacled cobra, Indian Common krait, Indian Russell’s viper, and Indian Saw-scaled viper.
SGLT2i 💊 are emerging as a promising agent to prevent and ⤵️the progression of DKD
Ever wondered
What do they do to electrolytes❓
Why r these diuretics not associated with electrolyte depletion❓
What is the impact of SGLT2i on Na and water hemostasis?
First, let’s revisit, how Na and glucose are handled in the nephron 📜
💥100% of the filtered glucose is reabsorbed along the nephron (90%, via SGLT2 in PCT)
💥1 Na+ ion for every glucose molecule gets absorbed from the lumen
💥In PCT 60 - 80% of sodium is reabsorbed