Yes. We've been walking blindfolded into uncharted territory. Not only the huge range of action of SARS-CoV-2 via ACE2. Not only the transmission rate. But also the great capability of the virus to evolve fast, relentlessly. It was already clearly evolving in China and Lombardy
The other two severe coronaviruses which spilled into humans, SARS CoV and MERS CoV, never became pandemic. We didn't learn enough from them. What we clearly knew, such as about high morbidity levels, wasn't considered appropriately at the beginning of the pandemic.

#longSARS
Covid doesn't have a huge mortality rate, especially with vaccination. It does have, though, a monstrous morbidity rate. This is evident from current research, patient testimony, and the virus' nature itself. You can't pretend a virus which uses the ACE2 receptors |
which are widespread throughout the human body, and has great ability to disrupt the immune system, not to have huge morbidity levels. As we are in uncharted territory, cutting surveillance and "letting it rip", is deranged policy

#LongCovid

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More from @elisaperego78

Apr 11
It is now reported Queen Elizabeth is suffering from #LongCovid symptoms, like severe exhaustion. I find it troubling, from the interview, she seemed not really aware of the possibility of Long Covid even after a "mild" case, at the beginning

🧵

thedailybeast.com/queen-elizabet…
Apparently, the Queen insisted to keep working through symptoms in the early phase of the disease. She is now asking for confirmation that feeling rough after covid is "normal". I don't know how much of this is fully genuine (it's the press!). But just a few pointers.
#LongCovid is not uncommon. It can happen even after a "mild" case and even after a post-vaccination infection. Feeling rough, exhausted and sick is not unheard of for viral infections. This is especially the case of a severe, pandemic disease like covid.
Read 7 tweets
Apr 11
Your daily reminder that covid is not becoming "endemic".
In epidemiology, endemic means present in limited geographical area, at a baseline level, with no external imput.
Covid is a pandemic disease.

🧵
SARS-CoV-2 is evolving fast. It's not present at a stable, baseline level in any area. Cases go up and down hugely, and (for now) are coming in waves. International travel and a deeply interconnected world make it impossible to avoid "external input". Variants may travel globally
I see the chart tries a reclassification of influenza as an "endemic" disease (we all know influenza doesn't meet the criteria I outlined above!). And, lol we are really in an age of speed-of-light re-writing of epidemiology, public health, and recent pandemic history
Read 6 tweets
Apr 11
Many cyclists and bikers, including top C. Sagan and V. Nibali, are reporting prolonged symptoms and/or multiple SARS-CoV-2 infections. These are having a severe impact on their careers

"We probably underestimated the effects of the virus"

#LongCovid

meteoweb.eu/2022/04/colbre…
Note how the article (in Italian but one of the many on the topic) avoids to mention #LongCovid directly, although the link with covid is addressed. It also speaks of a mysterious flu-like illness that would have been massively hitting professionals in the last few months (uhm)
Thanks @Jennings18Karl for mentioning this issue a few days ago, too! This article in Italian is more explicit about the covid link
Read 4 tweets
Apr 11
Extremely concerning evidence from countries under scrutiny since 2020 for their inadequate approach to SARS-CoV-2: e.g. the UK in 2022, 160,000+ dead, 1.7+ million with #LongCovid, healthcare on the verge of collapse, chaos even at the airports!
We need accountability
This is by Hancock is basically the same tweet by @sajidjavid who succeeded Hancock as Health Minister. Obviously, both supervised the extremely faulty strategy who led to death, social disruption and #LongCovid in the UK

I answered here:

The disparaging of zero covid by those who chose the opposite strategy is obviously necessary. They have to defend themselves, especially if future inquiries into their choices are being carried out in the future

They are desperate to prove zero covid was impossible. It wasn't
Read 4 tweets
Apr 11
It was already established in the biomedical literature in 2020 that covid is not a respiratory disease only. The virus spreads via a predominantly airborne route i.e. through the air as cigarette smoke.
But the disease is multi-systemic, with a strong cardiovascular component.
Baffled governments and policy makers are still claiming covid is a respiratory disease, after the publications of hundreds of thousands of scientific publications on the topic.
The morbidity i.e. long term health effects i.e. #LongCovid is also massive and of severe concern.
Many people in the world including many children in the UK itself remain unvaccinated. Letting such a dangerous virus to spread unchecked will impact other countries too, including those less able to access vaccination.

#LongCovid
Read 4 tweets
Apr 11
I wouldn't be proud if I were Fauci to be in agreement with Wen. The world need competent, brave, emphatic leadership. We can't "live with the virus" as these people mean i.e. by accepting mass disability, increasing inequalities, healthcare disruption, #LongCovid, and death

🧵
Policy makers need to be crystal clear about the reality and severity of covid, the nature of the virus, its propensity for immune escape and fast evolution, and the great morbidity risk = #LongCovid. They need to be open about the risks of symptomatic breakthrough infections.
They need to be honest about the risk of #LongCovid after breakthrough infection. About inequalities around getting the vaccine and antivirals. About the chaotic disruption in every day life that will come with repeated infections, even if such infections are "mild" in many.
Read 6 tweets

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