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Eric Feigl-Ding Profile picture
@DrEricDing
Apr 23, 2022 • 10 tweets • 5 min read • Read on X
WANING—After 3 doses, effectiveness of Pfizer vaccine against Omicron (BA1) hospital admission was 📌85% at <3 months but fell to 📌55% at 3-5 months. For ER admission, VE of 3 doses was 📌77% at <3 months but fell to 📌53% at 3-5 months. 2 doses worse. 🧵
thelancet.com/journals/lanre… Image
2) Trends in waning against SARS-CoV-2 outcomes due to the delta variant were generally similar, but with higher effectiveness estimates at each timepoint than those seen for the (BA1) #omicron variant.
3) Analyses were done for 11,123 hospital or ED admissions at Kaiser… ➡️effectiveness of two doses against the omicron variant was 41% against hospital admission and 31% against emergency department admission at 9 months or longer after the second dose. 👀
4) we have long known 2 shots has very poor efficacy against #Omicron. It was low ever since it emerged. Booster is still very very very important for protection with 70% efficacy against symptomatic infection early on.
5) there’s advantages to mixing vaccine types for boosters. See older thread 🧵 below.
6) and it seems the Moderna booster is very different than the Pfizer booster. The T cell response seems different too. Many experts advise mixing up the vaccines for broader immunity coverage.
7) And what is the efficacy protection against #Omicron mortality with 2 shots? It’s now only 59%! But with a 3rd shot booster— surges to 95%! You don’t want to stay at 59% protection. You want 95% with a booster folks! Please I beg you all. #getboosted
8) And again, data from 🇬🇧 shows, have had a full Moderna 2 shot series is much stronger than 2 shots of Pfizer or AstraZeneca. The data shows it’s over and over again. It’s the vaccine that has the least relative waning against #Omicron.
9) Here is an example of misinfo/ misunderstanding about vaccine efficacy / effectiveness. this is claim of 50/50 chance is a grave misreading. 55% vaccine effectiveness means it cuts risk by 55. So if instead of 2 in 100 with severe disease, it is lowered by half to ~ 1 in 100. Image
10) in case I’m not clear— the Moderna vaccine seems much stronger than the Pfizer vaccine. Even if the Booster for Moderna is just 50 mcg instead of Pfizer’s 30 mcg, it’s still likely stronger. Also the upcoming age <5 Moderna vaccine will be 25 mcg vs just 3 mcg for Pfizer.

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More from @DrEricDing

Eric Feigl-Ding Profile picture
Aug 14
JUST IN— W.H.O. Declares Global Emergency Over New Mpox Outbreak. The threat this time is deadlier. Since the beginning of this year, the Democratic Republic of Congo alone has reported more than 14,000 mpox cases and 524 deaths. Those most at risk include women and children under 15. The outbreak has spread through 13 countries in Africa, including a few that had never reported mpox cases before.

(Gift 🎁 link)
nytimes.com/2024/08/14/hea…Image
2) public health emergency of international concern— Also known as PHEIC, this is a status given by WHO to “extraordinary events” that pose a public health risk to other countries through the international spread of disease.

cnn.com/2024/08/14/hea…
3) The Africa Centres for Disease Control and Prevention declared the outbreak a public health emergency of continental security the day before — the first such declaration by the agency since its inception in 2017.
Read 15 tweets
Eric Feigl-Ding Profile picture
Jul 19
Concerning—CDC now says that 42 states are seeing rising rates of #COVID19 again—with levels high or very high in 35 states (and rising). COVID wastewater levels have already surpassed last summer’s peak and climbing fast. #CovidIsNotOver
cdc.gov/forecast-outbr…


Image
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2) Substantial 28% increase in one week. Question is how high it will go. It’s a new variant (mostly KP2 and KP3 and JN1), which are evasive against past infection and past vaccines.
3) COVID is surging in many countries worldwide. Eg in Italy where deaths are also climbing once again. New variants, new surges.
Read 4 tweets
Eric Feigl-Ding Profile picture
Jul 3
A girl using cover name JANE DOE testified under oath at Ghislaine Maxwell’s criminal trial that she was introduced to Trump by Jeffrey Epstein when she was 14 years old. Pass it on.
Trump’s name appears 7 times in Epstein’s latest files. They regularly called each other according to phone logs. Trump says Epstein is a “terrific guy”. And he traveled on flights, according to logs, to Epstein’s island multiple times.
3) THIS STUFF IS NEW—not old Epstein-Trump info. New information regarding Epstein's child trafficking activities was released 7/2/24. Documents from 2016 are now out of date and do not show the depth of Trump's dealings with Epstein... READ MORE:

nymag.com/intelligencer/…
Read 4 tweets
Eric Feigl-Ding Profile picture
Jul 2
Reminder—Trump had expressed executing people on many occasions while President, according to his own Attorney General. Now the Supreme Court has green lit any official act with full presidential immunity. Germany did the same in 1933. It turned out great.
2) If we ignore history, we are bound to repeat it. How Germany became Nazi Germany in 1933….
3) And the U.S. military will become Trump’s official personal army.
Read 8 tweets
Eric Feigl-Ding Profile picture
Jul 1
American Democracy is dead. Long Live the King. The King can now “assassinate you, officially”.

By @ElieNYC
thenation.com/article/societ…
Image
2) Laws aren’t really laws anymore to the President of the United States. Who do you want as president now?
3) American democracy had a great 240-year run. Too bad it’s now sorta over after today’s SCOTUS ruling.
Image
Read 6 tweets
Eric Feigl-Ding Profile picture
Jun 23
📍 The New York Times Is Failing Its Readers Badly on Covid

📌“Example of ‘science opinion’ run amok in the [NY Times] is a piece… by Zeynep Tufekci, a commentator with no training in biological science or epidemiology… ➡️Tufekci plays into the hands of the anti-science politicians who now seek vengeance on the flimsiest of grounds.”

By GREGG GONSALVES and JOHN P. MOORE
thenation.com/article/societ…Image
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2) “Tufekci also adds to the ongoing pile-on about whether the directive to maintain a distance of six feet from others was needed. Although the precise distance was indeed somewhat arbitrary, there was no possibility of obtaining hard data in the relevant time frame. The six-foot distance was a reasonable assumption based on public health history, and the practice of social distancing for other respiratory pathogens, particularly those spread by droplets. It was also adopted in multiple other countries, for the same reasons.”
3) “The problem here isn’t that Tufekci is questioning the evidentiary basis of the six-foot rule—science and public health cannot progress if we don’t evaluate the results of our work. But that progress is more effective when grounded in good-faith inquiry, rather than the kinds of attacks Tufekci levels against government scientists for doing their best in desperate circumstances. This only serves to bolster the forces who seek to destroy the US public health infrastructure, not make it better.

Tufekci also leaves the impression that she alone realized SARS-CoV-2 was airborne early on. In fact, the debate about transmission was fast and furious within the scientific community at that time”
Read 9 tweets

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