#tbt This is Toshiko Yuasa, the first woman physicist from Japan. It's 1940 & with her science prospects at home blocked by gender prejudice, she'd managed to get into wartime Paris to do physics research... en.wikipedia.org/wiki/Toshiko_Y…
...The drawcard in Paris was Marie Curie's daughter, Irène Joliot-Curie & her husband Frédéric. Yuasa was inspired by their papers on artificial radioactivity.
Here's Toshiko & Irène at the Joliot-Curie home in 1941... en.wikipedia.org/wiki/Ir%C3%A8n…
...Yuasa was born in downtown Tokyo in 1909, the next-to-youngest of 7 children. Her mother came from a long line of poets, in the family of a renowned 19th century scholar, Tachibana Moribe. Her father was an engineer & inventor who worked at the patent office...
...In 1931 she became the first woman to study physics in Japan, at the only university that accepted women students. Yuasa graduated in 1934, publishing her first paper that year too.
She'd applied to get to Paris before the war started & gained a degree there...
...When the Allies landed at Normandy, as a citizen of an enemy country, Yuasa had to leave. She went to Berlin, where she built a double-focusing beta-ray spectrometer. She got back to Japan just before the atomic bombs fell, via Trans-Siberian Railway, with her spectrometer...
...Under US occupation, Japanese scientists weren't allowed to study nuclear physics. So she taught young women scientists - 3 of whom became physics professors, & lobbied for the 1st women's university. In 1949 she returned to Paris to be able to research..
...Yuasa lived in Paris for the rest of her life, & celebrated in Japan. She became a chief researcher @CNRS. There's more on her work in theoretical & experimental physics here: citeseerx.ist.psu.edu/viewdoc/downlo…
In 1962, she gained a PhD from Kyoto University for a thesis on beta-decay...
...Here she is in 1978, aged 68. She'd been coping with stomach cancer for a few years & died in 1980.
On the day she died, she heard a project she'd been promoting was funded: it was carried forward by Joliot-Curie's daughter & a scientist from Kyoto... archive.mith.umd.edu/gcr/text/text_…
...Yuasa also painted, wrote poems, popular essays about Paris, & advocated for French-Japanese collaboration. There's a prize in her name to enable young Japanese scientists to study in France.
More on her life: lib.ocha.ac.jp/archives/en/re… // 🧵 end

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More from @hildabast

Apr 27
When it hit me that I knew nothing about early women scientists in Ukraine, I went down a mind-blowing rabbit hole...
So hard to pick, but I whittled down to 15 amazing stories of women born before WWII.
Today, part 1, with the first 5 women 🧵 @PLOS absolutelymaybe.plos.org/2022/04/27/ear…
...This is Maria V. Pavlova (1854-1938), at her desk in the 1920s with fossils. She corrected an error in assumptions about the ancestry of horses... Image
...Sofia Okunevska-Morachevska (1865-1926) was an activist doctor - the 1st medically qualified woman in the Austro-Hungarian empire, not just Ukraine.... Image
Read 23 tweets
Feb 28
Such terribly sad news: the loss of Chris Del Mar, a giant of the Australian – and global – evidence community.
💔 for Tammy & family.
You'll hear a lot about this wonderful, lovable person & his amazing life ....
...Here's a quick overview from late last year, when Chris was awarded the Order of Australia - one of my faves because of the lovely family photo.... www1.racgp.org.au/newsgp/profess…
...I want to add to the remembrances & accolades for Chris, memories of a specific stream of his life - patient empowerment. From back in the early 2000s when we used to use this photo. He was the Chair of the Board of the consumer health information NGO I headed back then...
Read 5 tweets
Feb 2
1st Covid human challenge trial results shows it is feasible: 34 people were inoculated with a very low dose. It was enough to infect 18 people (53%) & 89% of them developed symptoms ...🧵 researchsquare.com/article/rs-112… HT @HelenBranswell
..Viral shedding quantifiable within 40 hours. They concluded up to 44% of infections would happen before virus can be detected. Results support 10-day isolation periods & professionally-administered LFA/RAT was "highly reliable in predicting the disappearance of viable virus"...
...The people were 18-29 years old, & stayed in individual negative pressure quarantine rooms. No safety signals in these first 28 days of follow-up. (They'll follow them for a year)...
Read 9 tweets
Sep 22, 2021
First phase 3 efficacy results for the Clover vax are out in a detailed press release. cloverbiopharma.com/news/83.html

Great relief: it's a critical vax for the COVAX supply. Protein subunit vax, with a Dynavax adjuvant & alum. Records on it: zotero.org/groups/2528572… ...1/n HT @lutl88 Image
...The trial has 30,128 participants in Philippines, Brazil, Colombia, South Africa, Belgium. All infections sequenced were variants. Because of vax programs in these countries, not many older people...2/n
...For people without previous SARS-CoV-2 infection, 207 tested positive & 146 of these sequenced so far. 73% were Delta (most of them), Mu, & Gamma...3/n
Read 15 tweets
Aug 11, 2021
🧵 recent studies on Covid vax in people who are immunocompromised: none are randomized trials. But first, 3 new trials are kicking off … 1/21
….Trial registered in Israel for 450 people with kidney transplants who didn’t have a strong response to 2 BNT-Pfizer doses: a 3rd dose, with or without reducing immunosuppressive treatment clinicaltrials.gov/ct2/show/NCT04… #IC …2/21
…Trial in the US for 200 people with kidney transplants who didn’t have a strong response to 2 doses of BNT-Pfizer or Moderna will get a 3rd dose of the same vax clinicaltrials.gov/ct2/show/NCT04… #IC ...3/21
Read 22 tweets
Jul 28, 2021
6-month followup for major BNT-Pfizer vax trial. While still blinded, overall vaccine efficacy was:

- against symptomatic Covid-19: 91.1% (89-93)
- against severe Covid-19: 96.7% VE (80-99.9)

...1/n
medrxiv.org/content/10.110… (preprint)
...Vaccine efficacy peaked before 2 months after dose 2, & then waned somewhat over time: from 4-6 months it was 83.7% (75-90). They estimate it declines by about 6% every 2 months... 2/n
...They analyzed the infections in South Africa - there were 800 people there (401 vaxed). All 9 people with Covid-19 were in the placebo group: 8 of them were infected with the Beta variant... 3/n
Read 7 tweets

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