Thread by @MackayIM

"Almost 40% of patients that shared a hospital room with someone with occult SARS-CoV-2 infection became infected.
The risk was highest for patients sharing rooms with individuals with very low Ct counts. Others"
#ViralLoad #InfectiousDose

"although nosocomial spread of SARS-CoV-2 is relatively rare with standard infection protocols, there is a high risk of transmission for patients in shared hospital rooms if their roommate is acutely infected."
academic.oup.com/cid/article/74…

"PCR-positive results in contacts independently increased with higher case viral loads (lower cycle threshold [Ct] values)"
"Overall, 85.4% PCR-positive contacts had an index case with an estimated viral load of ≥10 000 RNA copies/ml (Ct ≤ 24.4)."
#ViralLoad #InfectiousDose

"Using the estimated sensitivity by viral load of
4 LFDs, we estimate they would detect 83.0%–89.5% of cases leading to onward transmission."
academic.oup.com/cid/article/74…