To support biosafety and biosecurity investigations into the introduction of SARS-CoV-2 into the human
population through a laboratory incident; the SAGO notes that....
the need to access to & review evidence of all lab activities (both in vitro & in vivo studies) with coronaviruses including SARS-CoV-2-related viruses or close ancestors & the lab’s approach to implementation & improvement of lab biosafety & biosecurity.
3. POLITE SAGO
"As it is not common practice to publish the institutional implementation of biosafety & biosecurity practices of individual labs in peer-reviewed scientific journals, additional information will need to be obtained and reviewed to make conclusive recommendations"
4. OBJECTIONS OVERULED
SAGO agreed (apart from 3 objections) that:
"it remains important to consider all scientific data available either through published or other official sources to evaluate the possibility of the introduction of SARS-CoV-2.. through a laboratory incident"
5. SAGO RECOMMENDS..
"Additional investigations should be carried out with the staff... in the laboratories working with SARS-like viruses in Wuhan and potentially with those located worldwide where early COVID-19 cases have been retrospectively detected before 2020"
6. SAGO, BETTER LATE THAN NEVER...
"This would provide an opportunity for more specific questions to be asked related to biosafety and biosecurity management of SARS-like virus studies at the individual laboratories"
"This would provide an opportunity for staff and scientists to give their perspective on the
possibility of a laboratory incident and whether any occupational illnesses occurred before
the recognized start of the pandemic."
8. OH SAGO, WHAT A NICE SURPRISE!
"Examine regulatory biosafety or biocontainment standards and biocontainment levels and risk-mitigation strategies for SARS-like CoV-associated studies"
9. WAY TO GO, SAGO!
Determine occupational hazards intrinsic to labs working with SARS-like CoV & nature of studies performed before 1st reported COVID-19 cases in Wuhan, if they involved reverse engineering/GOF/ genetic manipulation/animal studies with strains of SARS-like CoV
10. SAGO's 1, 2,3
1.
Determine risks associated with field-related activities, such as the collection of specimens from bats or other wildlife sources and the potential for SARS-like CoV infection of staff.
11. SAGO's 1, 2,3
2.
Evaluate potential scenarios where a breakdown in biosafety or biosecurity procedures led to a possible laboratory-acquired infection with the studied pathogen.
12. SAGO's 1, 2,3
3. Determine if there were any biocontainment breaches or lab incidents or accidents with SARS-like coronaviruses in BSL2/3/4 labs that may have resulted in escape and/or infection of staff members prior to December 2019 where early cases were detected in China
13. SAGO PROPOSES
"Global engagement with scientists working on SARS-like viruses in bats to seek input on the molecular biology and evolution of these viruses and to identify potential biosafety issues"
14. SAGO ALSO PROPOSES...
15. SAGO INTEGRITY
Despite scurrilous attempts by Dr. Dedkov, Pasteur Institute Russia, Dr Morel, MOH, Brasil & Professor Yungui Yang, Beijing Institute of Genomics to delete mentions of a possible lab leak, it seems that SAGO acted with certain integrity in this investigation.
16. Dr. Dedkov's "DeadCov Position"
was summed up here in Xinhua in 2021:
Interview: Politicizing emergence of new viruses hinders scientific research: Russian expert
"All of the scientists joining this process understand the external pressures, scrutiny & visibility of the process. It may be our last chance to understand the origins of this virus in a mutually responsible way”
Overall, this report by SAGO is good news for those who remain convinced that SARS-COV-2 resulted from a Lab Leak, but how it translates into reality remains to be seen, as with cooking a SAGO pudding
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1. The long awaited 293 questions for Dr. Ralph Baric have finally been completed and shared! Long live the quest for truth! You are hereby invited to read the sharpest, most lethal 293-question dossier ever built.
1. "These tiny fragments were far smaller than cells and even smaller than many viruses. Some were close to the size of DNA strands. Under high magnification, she noticed small hooked shapes with sharp points.
✴️2. OVERLOOKED
"She realized that the plastic in human brains was not only present, but surprisingly small. The fragments were so tiny that common diagnostic tools could not detect them. Pathologists had likely been overlooking them for years."
"The two original samples showed a strong link between plastic particles and dementia. As Bearer expanded her work to ten more donated brains, she found plastic in every single one. None were free of synthetic fragments."
Unfortunately, there is no direct proof provided by Redfield in this new interview, but he cites engineering features, early data, and classified information.
🧵3. Summary of Redfield's Statements
(on SARS-CoV-2 Origins & Cover-Up)
He claims SARS-CoV-2 originated from GOF research in a lab and emphasizes a significant US role alongside China.
He views this as a major biosecurity failure with ongoing suppression of transparency.
"Of note, the spike protein of this novel bat coronavirus possesses a functional FCS at the S1/S2 junction with a unique amino acid sequence motif (RDAR) that differs from that found in SARS-CoV-2 (RRAR) by only 1 amino acid."
"The molecular biology capabilities of WIV & the genome assessment are consistent with the hypothesis that SARS-CoV-2 was a lab-engineered virus that was part of a bank of chimeric viruses in Zheng-Li Shi's laboratory at WIV that escaped from containment"
Between 2017 and 2019, WIV created full-length a infectious clone in pBAC-CMV using an unpublished bat Coronavirus genome as template (BatCoVX)
page 85
3. Hypothesis 3:
Between 2017 and 2019, WIV created chimeric Bat-CoV-X viruses using the pBACCMV-BCOVX backbone and swapping out key cassettes with other bat Coronaviruses (RBD, RBM, etc.) and adding additional features such as a furin cleavage site