Dr Aditya Ganguly Profile picture
Jun 17 12 tweets 3 min read
1) Bell's palsy (BP) is typically defined as an IDIOPATHIC unilateral LMN type CN7 palsy.

It is named after the Scottish neurophysiologist, Charles Bell. (vide infra)
2) But an LMN type CN 7 palsy is NOT the same as Bell's palsy.

It is merely the idiopathic form, often thought to be due to herpes or varicella induced direct nerve damage or as post infectious demyelination.
3) There are certain RED FLAGS in the diagnosis of an LMN type CN 7 palsy.

1. Vesicles on the tympanic membrane or ear canal (Ramsay Hunt syndrome type 2)

2. Bilateral involvement - Lyme disease, sarcoid, GBS, Melkersson-Rosenthal syndrome, Mobius syndrome etc!
4)
3. Systemic manifestations --> fever, bleeding diathesis, rash etc --> we had a case of leukemia with middle ear bleed (hemotympanum) --> facial nerve palsy.

If you are in the US, you must look for the rash of Lyme disease!
5)
4. Sudden onset with maximal severity at onset
5. Insidious onset of symptoms
6. Progressive worsening beyond 3 weeks
7. No recovery at all beyond 4 months

These are hard RED FLAG signs for Bell's palsy.
6) The last 3 red flags are important to rule out --> a tumour of the pontomedullary junction (intra or extra axial), CP angle tumours, internal acoustic canal, middle ear and the parotid gland +/- mets to the same!
7) Rarely, a lesion restricted to the lower motor branches of the facial nerve (that supply the superficial muscles of facial expression) --> can mimic a UMN type of CN 7 palsy as well --> beware of these cases!
8) Ear discharge +/- earache +/- ear fullness --> you must rule out middle ear pathology like a choleasteatoma/COM.

Severe infection in these causes can cause petrous ridge osteomyelitis of the temporal bone --> Gradenigo syndrome --> triad of CN 6,7 palsy, retroorbital pain
9) One must never forget to ask about tinnitus and vertiginous sensations +/- frank dizziness.

Since CP angle tumours like vestibular schwannoma are very slow growing, the asymmetry of vestibular input develps very slowly --> patients can complain of only very mild dizziness!
10) As we can see, Bell's palsy is very different from a CN7 palsy of the LMN type.
Missing out on important diagnoses and labelling something as an idiopathic variety without a proper evaluation ---> NO NO!

#MedTwitter
#NeuroTwitter
#JustinBieber
#RamsayHuntSyndrome
Please retweet if you find this useful. I have seen many cases of misdiagnosed CN 7 palsy (LMN type) in my residency --> it is important that physicians not miss the red flags --> this will optimize outcomes for patients.
Here is a case of a pontine stroke causing isolated facial weakness mimicking Bell's palsy!
jmedicalcasereports.biomedcentral.com/articles/10.11…

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Dr Aditya Ganguly

Dr Aditya Ganguly Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @AdiG1993

Jun 19
1) Have you ever seen a case of rabies?

I saw two cases 5 years back and they have stayed with me since.

I do not fear any disease per se but I am not ashamed to say that I dread rabies --> it is a terrible affliction.
2) The first patient was a small child of around 7 years old --> he had been bitten by a street dog around 1 month back. But his family had opted for natural healers.

When he was brought in, he was crying uncontrollably with a terror stricken expression on his face.
4) The delirium worsens over a period of hours to days as the patient gradually lapses into a coma, if the autonomic storm doesn't kill him or her first.

Rarely, the patients may develop a form of ascending paralysis mimicking GBS --> paralytic rabies.
Read 13 tweets
Jun 18
1) As an intern, GP or a gen med resident, you are constantly exposed to MR imaging of the brain. This is a complicated imaging modality that requires a radiologist for optimum analysis and reporting. But you must know the basic sequences and how to identify them.
2) The five most common sequence that we use in internal medicine are the T1 (with or without contrast), T2, FLAIR, DWI and ADC sequences. SWI/GRE sequences are also used in certain cases.
3) First check whether the soft tissue of the scalp and the skull (black) are visible or not --> if yes, you are dealing with T1,T2 or FLAIR.
Read 10 tweets
Jun 17
1) The Agnipath recruitment scheme has spawned chaos aross states --> but it is symptomatic of a larger problem.

The system of pension is economically unviable in the long term --> lifespans have increased disproportionate to retirement ages across economies.
2) Visual capitalist has created an illustrative infographic to explain this particular problem --> they call this the financial equivalent of climate change!
visualcapitalist.com/pension-time-b…
3) There are only three outcomes possible

1. Pension systems will cease to exist.
2. People will have to continue working into their 90s.
3. The reproductive rates will have to go down as most people go childless --> but this will slow down in the economy decades hence.
Read 5 tweets
Jun 10
1) I was recently contacted by a young man who was unsure of pursuing NEET since he had a tumor during his preparatory phase which had badly derailed his studies.

He was worried that he had lost 'a lot of time' and that his peers were far ahead of him!
2) I told him something I had learnt from one of my mentors long back --> No plan in life, as in war, survives first contact with the enemy!
3) This is his life and his glory or his failure will be his alone --> he has faced what others (including myself) could not have dreamt of --> in my opinion, he is a warrior!
Read 4 tweets
Jun 8
1) Cephalosporins are a commonly used class of antibiotics --> what's not so commonly known is that some members of this drug class can cause major bleeding complications!

4 groups of cephalosporins have been implicated in this problem!
2) This is based on the different side chains attached to position 3 of the cephem nucleus!
The first and largest group is the NMTT (N-methylthiotetrazole) side chain containing group --> cefamandole, cefotetan, cefmatazole, moxalactam and cefoperazone!
3) Other groups include MTDT and HTT side chain containing cephalosporins as well as cefoxitin which doesn't have any side chains attached to the 3 position of the cephem nucleus!
Read 10 tweets
Jun 6
The youngest STEMI (heart attack) patient I ever saw was aged 23.
He was obese, hypertensive,never excercised and drank soft drinks everyday! He had lost his father and uncle to STEMI as well! We suspected FH but there was no evidence!

Young age no longer rules out ACS!
FH --> Familial hypercholesterolemia, the most common AD genetic disease --> problems with the LDL receptor --> your liver cannot clear LDL --> LDL laden cholesterol gets oxidized (more in Indians, African Americans and Hispanics) --> atherosclerosis!
Statins usually work by reducing HMG CoA reductase which helps in cholesterol synthesis in the liver --> so the liver draws in more chol. from the LDL in blood using LDL receptors. They may/may not work in FH, depending on how badly the receptors are affected.
Read 6 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(