Thread by @wong_yujun

#ILC2022 @EASLedu @EASLnews @ebtapper @BloomPringle @Apichatka @markakismd @MartaBAfonso @LouisHSLau @jlouissaint89 @ajay_duseja @salvatore_piano

https://twitter.com/wong_yujun/status/1540255305270931456

🔥#ACLF-3: early vs late transplant @JosephAlukal

👉UNOS database: n=3,498
✅Better 90-day and 1-year survival for early LTx (<7 days)
🤔 Selection bias who goes for early vs late LTx?

#ILC2022 #Livertwitter @EASLedu @EASLnews
@VinaySundaramMD @RajivJalan1 @DrLiver @ebtapper

🔥Urine NGAL predicts response to Terlipressin/albumin in HRS by Dr Carmine Gambino

N=162 #cirrhosis, 🇮🇹
AKI>48hrs
urine NGAL:
⏫ ATN-AKI
⬇️ in Terli responders
💡NGAL>220 predict 90-day Mortality (AUROC: 0.85)

#ILC2022 #Livertwitter @salvatore_piano @ProfPaoloAngeli

Hospitalized #cirrhosis 🌎 study by @JasmohanBajaj
n=1,383,

✅Inpatient mortality 15%
✅Inpatient transplant 3%
✅MELD-NA, infection predicts #organ failures (🧠,🫁,🫀, AKI)

👉Better outcomes in high-income countries #disparity

#ILC2022 #Livertwitter @ashok_doctor

@EASLedu @EASLnews @sconglymd @stephentbarclay @ebtapper @BloomPringle

Can urine biomarkers (CysC & uNGAL) predict AKI? by Dr Rakhi Maiwall

n=369 #cirrhosis, 🇮🇳
✅urine CysC & nGAL
🎯 AKI by D7, CKD
👉AKI at D7 80%, CKD 46%
⏫ uGAL & alcohol predict AKI at D7

#ILC2022 #Livertwitter

🤔Can ammonia predict #ACLF in stable outpt #cirrhosis? by Dr Maria Pilar Ballester

✅Most have portalHTN, 11% had #ACLF

💡Ammonia >1,4xULM predict:
✅Organ failures (liver, kidney,🧠 , 🫁 )
✅#ACLF grade
⏫Mortality

#ILC2022 #Livertwitter @DebbieShawcros1 @RajivJalan1