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Helen Branswell 🇺🇦 Profile picture
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Jul 23 • 10 tweets • 8 min read
1. A #monkeypox 🧵
The US has surpassed the UK in #MPX cases, trailing only Spain at this point, I believe. Friday's tally from @CDCgov is 2891 cases. A couple of weeks ago the tally grew by about 50 cases a day. Now it's hundreds — nearly 400 today.
2. At a White House briefing late today, Jennifer McQuiston from @CDCgov said 99% of the US #monkeypox cases are gay, bisexual & other men who have sex with men. CDC knows of 2 cases in children (household transmission), 8 cases in cisgendered women & 5 in transgendered men.
3. In the UK, the #monkeypox case total is 2208, the vast majority of which were detected in England. @UKHSA updates its case count on Tuesdays & Fridays; today's total was only up 71 cases from what HSA reported on Tuesday.
4. In fact, @UKHSA reported Friday that it believes transmission in the UK has slowed and may be leveling off.
The percentage of cases in London, previously at about 75%, has declined & is now at about 66%.
5. @UKHSA has been watching #monkeypox cases in women as a proxy for a sign that transmission might be moving beyond gay, bisexual & other men who have sex with men. So far modeling suggests it has not, but the trend is being closely watched.
6. Of the 13 women in the UK who have been diagnosed with #monkeypox, 4 have needed hospital care for their symptoms. Women have had fever, swollen lymph nodes, genital lesions & lesions in the mouth & throat.
7. @UKHSA has surveyed some of the people diagnosed with #monkeypox in the U.K. More than 96% are gay, bisexual & other men who have sex with men. 31% have had 10 or more sex partners in the last 3 months. More than half have had an STI in the past year.
8. This is an interesting statistic that illustrates the challenge public health authorities have trying to stop #monkeypox transmission by finding the contacts of cases. Only 8% of known cases were listed as a contact of a previous case.
9. The latest @UKHSA #monkeypox technical brief has lots of interesting information, including this table on the test positivity rate by population groups. Nearly 54% of adult men tested are positive. For women, it's just over 2%.
They classify males 15 & older as adults!
10. The newest @UKHSA #monkeypox technical brief is here: gov.uk/government/pub…
Last note: @WHO will announce tomorrow if #monkeypox will be designed a public health emergency of international concern.

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More from @HelenBranswell

Helen Branswell 🇺🇦 Profile picture
Jul 22
1. A short #Marburg 🧵
@WHO issued an update on the cases of Marburg in Ghana today. It didn't declare the outbreak over, but it did say that all 108 known contacts of the 2 cases have gone through 21 days without becoming sick, so they are in the clear. Good news. Image
2. However, investigations into the two men — both of whom died — have not revealed how they contracted #Marburg. Hard to rule out the possibility there might be other, as yet undetected cases. This is the first time Marburg has been detected in Ghana. Image
3. Both men were from the Ashanti region of Ghana, the most heavily populated part of the country. One of the men — the first to seek care — had traveled to the western part of Ashanti before he became ill & he was buried in the Savannah region. It was not a safe burial. Image
Read 5 tweets
Helen Branswell 🇺🇦 Profile picture
Jul 20
1. A short #MPX 🧵
The U.S. #monkeypox case count is now 2,323. Cases have been reported from all but 7 states: Wyoming, Montana, North Dakota, Mississippi, Alaska, Vermont and Maine. cdc.gov/poxvirus/monke… Image
2. The latest #monkeypox report from @ECDC_EU & @WHO_Europe is out. 36 countries in the European region have reported 10,604 cases. As usual, there's lots of interesting data in this report. monkeypoxreport.ecdc.europa.eu
3. Some stats:
- 42% of #monkeypox cases are 31 - 40 yo.
- 99.5% are male.
- 38% are people living with HIV (of cases for whom HIV status is known, ~1/5th of all cases)
- 94.5% had a rash.
- 31 were health workers, but they aren't thought to have been infected at work.
Read 5 tweets
Helen Branswell 🇺🇦 Profile picture
Jul 19
1. #ACIP, @CDCgov's vaccine advisory panel, meets today to study the data on Novavax's Covid vaccine and will vote on whether to recommend its use.
I'll be live tweeting the meeting.
If you want to watch the meeting yourself, it's viewable here: video.ibm.com/channel/VWBXKB…
2. Several members of #ACIP appear not to be attending today's meeting. Perhaps they'll join later but I think there are at least 4 of the 15 voting members not present.
3. Make that 3 missing members. I think.
#ACIP
Read 37 tweets
Helen Branswell 🇺🇦 Profile picture
Jul 14
1. Short #MPX 🧵
There's an interesting #monkeypox paper today in @Eurosurveillanc from researchers in Barcelona. They took 147 specimens from 12 MPX patients, sampling saliva, semen and feces as well as skin/lesion samples and swabs of the throat and anus.
2. They found a high level of positivity among those samples — including finding #MPX DNA in the saliva of all 12 patients in their study. They also found #monkeypox virus DNA in semen (7/9 cases), urine (9/12 cases) and feces (8/12 cases). This raises an obvious question.
3. Sadly, this paper can't answer that question, which is: Can #MPX be transmitted through contact with bodily fluids/products? It can't answer it because the researchers didn't try to grow virus from the specimens, so it's not clear if this was viral debris or infectious virus.
Read 8 tweets
Helen Branswell 🇺🇦 Profile picture
Jul 13
1. A thread on #PediatricHepatitis of unknown etiology.
@WHO issued an update today. It reports that 35 countries have reported 1010 cases. There've been 22 deaths (2%) & 46 (5%) of the children have needed liver transplants.
2. @WHO says it appears that the trend of cases is decreasing, but notes this should be interpreted with caution because there are reporting delays, likely under-reporting, and limited surveillance for such cases in many countries.
3. To that end, @WHO has launched an effort to try to assess whether there is a true increase in #PediatricHepatitis cases in the past 10 months or so. This comes on the heels of data from @CDCgov showing there has not been an increase of liver transplants among kids in the US.
Read 7 tweets
Helen Branswell 🇺🇦 Profile picture
Jul 7
1. Short #MPXV thread, based on data from @WHO_Europe & @ECDC:
The Euro #monkeypox outbreak continues to grow. Of +5200 cases reported here, 29 were women — which seems to be an increase. 15 health workers among cases; not clear if exposure was on the job.
monkeypoxreport.ecdc.europa.eu
2. This may not be new-new, but I haven't noticed this previously: @WHO has pushed back the date on its case definition for suspected #monkeypox cases. They'd previously said March 15; now saying since Jan. 1. Suggests they believe the outbreak started earlier.
3. These regular #monkeypox updates from @WHO_Europe & @ECDC_EU contain really useful information, like this breakdown of symptomology among cases.
Read 9 tweets

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