1. #Marburg: Concerning details from @WHO about the Marburg outbreak in Ghana. The 2 newest cases (#3 & #4) are the wife & child of the first case, who died June 27. @SoceFallBirima says the child was infected through contact with the mother, not Case #1. The child has died.
2. The wife, #Marburg case #3, refuses to go to a treatment center where she can be safely cared for. She is in a prayer camp, where the practice of laying on of hands is used to try to heal people, @SoceFallBirima said. The response team is trying to negotiate her transfer.
3. This is a dangerous situation which could result in a number of additional #Marburg cases in the Ghana outbreak.
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1. The UK's #monkeypox total has climbed to 2,432 cases, up 224 since Friday. @UKHSA has now started presenting cases as either "Confirmed" or "Highly Probable." gov.uk/government/pub…
2. The number of women infected with #monkeypox is slowly ticking up. Women make up a tiny fraction of all cases, but it's unlikely that will remain the case. There've now been 18 women among the UK's cases.
3. @WHO_Europe regional director @hans_kluge issued a statement on #monkeypox today. Kluge suggested the number of cases among women & children is increasing. While some are household contacts of confirmed cases, sometimes there's no discernible link to a previous case.
1. #PediatricHepatitis: 2 groups of researchers in the UK have posted preprints that flesh out a new theory on what may be behind the apparent increase in cases of pediatric hepatitis of unknown etiology seen this spring in the UK & Europe & first reported in Alabama last fall.
2. The tl;dr version: It's complicated.
A combination of 3 factors, exacerbated by a 4th, is likely responsible for these cases of #PediatricHepatitis, the studies conclude. statnews.com/2022/07/25/new…
3. For a time, the leading theory was that these unusual cases of #PediatricHepatitis were caused by adenovirus 41, which was found in all the Alabama cases & a number in the UK. But the new theory suggests it's more complicated than that.
1. A #monkeypox 🧵
The US has surpassed the UK in #MPX cases, trailing only Spain at this point, I believe. Friday's tally from @CDCgov is 2891 cases. A couple of weeks ago the tally grew by about 50 cases a day. Now it's hundreds — nearly 400 today.
2. At a White House briefing late today, Jennifer McQuiston from @CDCgov said 99% of the US #monkeypox cases are gay, bisexual & other men who have sex with men. CDC knows of 2 cases in children (household transmission), 8 cases in cisgendered women & 5 in transgendered men.
3. In the UK, the #monkeypox case total is 2208, the vast majority of which were detected in England. @UKHSA updates its case count on Tuesdays & Fridays; today's total was only up 71 cases from what HSA reported on Tuesday.
1. A short #Marburg 🧵 @WHO issued an update on the cases of Marburg in Ghana today. It didn't declare the outbreak over, but it did say that all 108 known contacts of the 2 cases have gone through 21 days without becoming sick, so they are in the clear. Good news.
2. However, investigations into the two men — both of whom died — have not revealed how they contracted #Marburg. Hard to rule out the possibility there might be other, as yet undetected cases. This is the first time Marburg has been detected in Ghana.
3. Both men were from the Ashanti region of Ghana, the most heavily populated part of the country. One of the men — the first to seek care — had traveled to the western part of Ashanti before he became ill & he was buried in the Savannah region. It was not a safe burial.
1. A short #MPX 🧵
The U.S. #monkeypox case count is now 2,323. Cases have been reported from all but 7 states: Wyoming, Montana, North Dakota, Mississippi, Alaska, Vermont and Maine. cdc.gov/poxvirus/monke…
3. Some stats:
- 42% of #monkeypox cases are 31 - 40 yo.
- 99.5% are male.
- 38% are people living with HIV (of cases for whom HIV status is known, ~1/5th of all cases)
- 94.5% had a rash.
- 31 were health workers, but they aren't thought to have been infected at work.
1. #ACIP, @CDCgov's vaccine advisory panel, meets today to study the data on Novavax's Covid vaccine and will vote on whether to recommend its use.
I'll be live tweeting the meeting.
If you want to watch the meeting yourself, it's viewable here: video.ibm.com/channel/VWBXKB…
2. Several members of #ACIP appear not to be attending today's meeting. Perhaps they'll join later but I think there are at least 4 of the 15 voting members not present.