Thread by @JosephSassineMD

Happy to share our review of antiviral treatment of #monkeypox, co-authored with the amazing @EmilySiegrist4 and just published in @CIDJournal! @OUHealth @IDSAInfo @SIDPharm @PaulSaxMD #IDTwitter #TxID #TwitteRx #MedTwitter #OpenAccess

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academic.oup.com/cid/advance-ar…

In this paper, we review three antiviral agents with activity against #monkeypox:
1. Cidofovir
2. Brincidofovir
3. Tecovirimat
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For each agent we discuss:
1. Basic Pharmacology
2. Pharmacokinetic Data
3. Animal Data
4. Toxicity
5. Clinical Data in Humans
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We hope this paper will be of help to the physicians, pharmacists and others who are increasingly considering antiviral treatment of #monkeypox as the cases continue to rise.
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My personal favorite is Table 1, which elegantly summarizes all the info you will need on the frontline, h/t @EmilySiegrist4. Thanks to the @OU_Libraries we kept it open access for the entire medical community, so make sure to check it out!
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