Thread by @sarahhudsonuk

💥My top 10 learning points from the #ESCCongress 2022💥

A thread for cardiologists/general physicians

1) Addition of IV acetazolamide to IV furosemide in AHF results in 46% higher incidence of successful decongestion after 3 days

EVIDENCE: ADVOR nejm.org/doi/full/10.10…

2) Revascularization with PCI does not improve event-free survival in pts with severe LVSD over OMT alone
(HF cohort, not acute ACS pts or significant angina)

Evidence: REVIVED
nejm.org/doi/full/10.10…

#ESCCongress

3) In pts with rheumatic heart disease and AF, RCT evidence supports VKA use over rivaroxaban, with decreased composite of CV events and death with VKA and no increase in bleeding.

Evidence: INVICTUS nejm.org/doi/full/10.10…

#ESCCongress

4) There is no difference in outcomes taking antihypertensive medications in either morning or evening.

Evidence: TIME

#ESCCongress

5) Dapagliflozin reduces the risk of CV death or worsening HF in pts with mildly reduced or preserved EF.

Evidence: DELIVER
nejm.org/doi/full/10.10…

#ESCCongress

6) Treatment with a polypill containing aspirin, ramipril and atorvastatin after MI resulted in a significantly decreased risk of major adverse events than usual care

Evidence: SECURE
nejm.org/doi/pdf/10.105…
#ESCCongress

7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictive (target PaO2 9-10kPa) or liberal (Pa02 13-14kPa) oxygen strategy during mechanical ventilation.

Evidence: BOX

nejm.org/doi/full/10.10…

#ESCCongress

8) An ordinary smartphone can be useful to detect treatment-relevant AF, using the standard camera lens.

Evidence: eBRAVE AF

#ESCCongress

9) Metanalysis shows muscle symptoms are common in pts on statins, but 93% are NOT attributable to statins

Evidence: thelancet.com/journals/lance…

#ESCCongress

10) Metanalysis supports pts with Marfan Syndrome being given both ARB and BB to slow rate of aortic enlargement.

Evidence: thelancet.com/journals/lance…

#ESCCongress

Thanks to @escardio for putting on a great conference, and for maintaining a 'virtual' option alongside the in person event.

#ESCCongress