My first 1st author paper is out in @TheBJPsych ! We found out that psilocybin is superior in reducing rumination and chronic suppression of negative emotions compared to escitalopram. Big thanks to @RCarhartHarris and @LeorRoseman for the guidance. #Psilocybin #psychiatry #LSD 
Rumination and thought suppression are 2 maladaptive coping strategies and, despite appearing sort of opposite, they reinforce each others (suppressed thoughts usually come back stronger, fuelling rumination).
While psilocybin appeared superior to escitalopram in reducing both of those maladaptive strategies, we wanted to see if psilocybin was just superior of if the effect was specific.
Focusing on the groups who responded to the 2 treatments we found that rumination decreased in participants who got better in both conditions. Suppression only got better in psilocybin responders. In escit group suppression remained high even if people were much less depressed.
Analyses are exploratory but this suggests that rumination decreases more in function of depressive symptoms while thought suppression decreases are specific of psilocybin treatment. The 2 drugs work differently.
Big ups also to @sarahbuehler_ , @KettnerHannes, @RaduCatia , Bruna Giribaldi and @ProfDavidNutt for the help and contributions!
More here: doi.org/10.1192/bjo.20…
• • •
Missing some Tweet in this thread? You can try to
force a refresh
