This is @TheLancet report on the pandemic failures. #LongCovid a disease that has disabled, made ill for prolonged periods of time, and even killed hundreds of millions of people is only mentioned in a small piece at page 57. Which doesn't address the gravity of the disease
#LongCovid is not exactly "emerging" as we've known about it since 2020. It was known before the pandemic a great percentage of SARS survivors never recovered or were ill for years #longSARS. Failure to mitigate SARS-CoV-2 spread and to support survivors is a huge failure
The short report has some good points. But is also highlights "post traumatic stress disorder", "mental health" and an incomplete list of symptoms more than the devastating cardiovascular, metabolic, multi-organ etc. sequelae that we know are a key facet of #LongCovid since 2020
The report also mentions SARS-CoV-2 being on its route to becoming endemic. We don't have any real evidence this is happening. SARS-CoV-2 remains a pandemic virus. It is also an unstable virus, which is spreading and evolving at a truly worrying pace, leading to local epidemics
Failure to recognize the real burden of SARS-CoV-2, the severity of #LongCovid, and the needs for mitigations are yes! another failure. I would hoped a @TheLancet commission on "pandemic failures" and "moving forward" would have been more accurate in its reporting
Also, another problem in my opinion is to speak about #LongCovid only after three months of symptoms is something I don't support. People especially if with severe symptoms need an immediate diagnosis and treatment. Not waiting three months.
Another issue with the piece: it fails to underline the patient made origin of #LongCovid. The disease was identified by patient themselves. Isn't it a huge failure in pandemic policy that people left at home to live or die on their own, had to do the work of health bodies?
Sorry to self-cite, but here a piece by co-authors and I from 2020. We openly mentioned cardiovascular, thrombotic and multi-organ sequelae, and the enormous costs of #LongCovid. We knew. Isn't it a huge failure not to have acted on this information?
The study conducted by the two UK charities also found that people could develop #LongCovid on their 2nd (10%) or, more rarely, on their 3rd infection (1%). This survey reinforces evidence provided by patients and researchers that reinfections aren't benign
A pre-print from the Al-Aly VA team had shown that "repeatedly catching Covid appears to increase the chances that a person will face new and sometimes lasting health problems after their infection."
"However you slice it, there was never an instance where COVID-19 was milder than the flu," says Dr. Ziyad Al-Aly of Washington University in St. Louis, who has done research comparing COVID to the flu.
"We've never, ever in the history of the pandemic, in all our studies from the beginning until now, have found that COVID-19 is equally risky to the flu," Al-Aly says. "It's always carried a higher risk."
Some key publications from the @zalaly team on covid's dangers | @Nature 2021
"Our results show an increased risk and excess burden of a broad array of symptoms as well as multiple organ involvement among people with covid" [vs influenza]
Three major original "sins" of the pandemic failure, not in a particular order
Seeing Covid as a respiratory disease only
Denying airborne transmission
Failing to grasp the huge morbidity to come
Number three should be clearly considered and highlighted in the recent @TheLancet. We are still failing on it badly.
Of course, not that the others have been fixed, especially as regards airborne prevention
I'm more specific on why I picked those three (of course not the only ones!) 1. Airborne transmission: there was evidence both from SARS CoV and the early Wuhan-EU etc. data, that SARS-CoV-2 could be airborne (it was of course! And airborne scientists showed it soon enough)
"Premature ovarian failure as a #LongCovid sequelae"
[the study] reports the case of a 34 year-old woman who contracted SARS-CoV-2 twelve months before, and presented with irregular periods and infertility as a likely post-covid sequelae.
🧵
The patient didn't have a notable history of obstetric issues prior to covid. She already had a child. She suffered from "moderate" acute covid, which led to admission with ground glass opacities in the lung. She had suffered from hypomenorrea and irregular periods since.
The patient reported inability to conceive. Her partner was found to be fertile and with no sexual dysfunction. Raised C reactive protein at the time of evaluation for apparent infertility suggested to the authors prolonged inflammation in #LongCovid.
“Becoming chronically ill can be difficult and challenging. Be kind.”
I talked to the @EveningStandard and A. Jagani about school accommodations for children living with #LongCovid
“Schools must
allow exible hours, personalised
schedules, and homeschooling.
Long Covid can present with a
relapsing-remitting pattern, with
periods of worsening and others of
improvement.”
[Long Covid] can also present as
an invisible illness, and a child can
be very ill without looking as such at
first glance.”
Covid~#LongCovid is~are among the most studied diseases in history. The amount of biomedical knowledge is staggering —if you read the literature and follow the science. Among the most cutting-edge techniques have been applied to Covid. Anyone saying otherwise is not up-to-date
Or they are intentionally presenting a picture inconsistent with where the science currently stands. Huge interests revolve around full recognition of #LongCovid: this is something which comes with huge costs (political etc) to those who promoted mass infection with a SARS virus
And note first-wave covid survivors already put together the early data and the research framework, which is leading to novel breakthroughs in #LongCovid research. It was the patient community to show covid was a multi-system, prolonged disease in many