I fail to understand how a disease —covid— could kill an estimated 15 million people in two years despite the prodigies of modern medicine and unprecedented safety measures — and leave almost all survivors basically unscathed.
Make no mistake. Morbidity from covid is huge.
Several lines of evidence — which are irrefutable especially when taken together — point to severe levels of prolonged disease, increased mortality risk, chronic illness, and disability following SARS-CoV-2 infection
First, the lived experience of survivors, who have been raising the alarm since the first wave and in subsequent waves. Patients identified, defined, and named Long Covid. Further research have fully confirmed those reports. We did say Long Covid was a catastrophe in the making
Second, the top health body in the world, the WHO, recognized Long Covid at the speed of light in August 2020 following patient advocacy —in a rather unprecedented move in medicine. I don't approve everything of the WHO. But you don't do this for a little fever, or tiredness
Third, serious research based on pathophysiology, analysis of health records, accurate symptom descriptions, and clinical signs in acute and Long Covid, show the devastating impact of this disease on the human body. Covid is now one of the most studied diseases in medical history
Fourth, socio-economic research and investigative journalism are shedding light on the link between covid morbidity —Long Covid—
and a long series of problems we're facing as a society, like labour shortages. Even key financial institutions have expressed their concern
Fifth, SARS. Many survivors of the first SARS were ill for years or never recovered. The SARS virus is called SARS-COV. The virus responsible for covid is called SARS-CoV-2. For a good reason. The two pathogens, while not identical, have a lot in common

#longSARS
We know other viruses have long-term health effects. Being SARS-CoV-2 particularly similar to SARS CoV, SARS should be our first reference point to start to grasp the sequelae of covid —although research on SARS long-term damage could have been done sharply imo. But it's enough
As regards those who think covid is like the seasonal flu, we have key research comparing the two diseases, such as recently the huge VA sample by the Al-Aly team: Covid is always more dangerous than seasonal influenza. And this isn't the only research on the topic, of course!
Sixth, sadly SARS-CoV-2 is a very unstable, fast-evolving pathogen. It has, especially now with "omicron", massive capacity to reinfect. We know from patient experiences/data and research that reinfections aren't benign, but actually increase the risks of sequelae.
Seventh, as I have shown in a few threads | for those who follow me! and others have also done e.g. @MeetJess mortality and morbidity from covid are also vast among personalities, singers, football stars etc. These are "rare" people. Big numbers there are a "red flag"
Eight, SARS-CoV-2 is airborne. It means, broadly speaking, it can spread in the air a bit like cigarette smoke. This confers it great capability to infect. Communication on this has been murky. Many people don't fully grasp it. We don't have clean air. We scrapped masks.
Ninth, airborne prevention and covid testing to protect healthcare settings aren't implemented! This means nosocomial infections (i.e. hospital related) and other infections in contexts like dentistry, are common. Vulnerable people are exposed, increasing the risks of sequelae!
Tenth, covid is bad enough. But, in collapsed healthcare systems like in the early red zones, people with severe covid have been literally phone triaged and left at home with no medical care. No medical care equals more damage, that is, more morbidity. This continues to this day
Eleventh, morbidity from SARS-CoV-2 infection #LongCovid is now recognized —sometimes under different names like post covid syndrome— by a significant percentage of countries and health bodies in the world. Including the very same White House and CDC! It's real
Twelfth, health institutions like the NIH, universities, but also private investors are putting billions into #LongCovid research. Not all of this money is spent fast enough, etc. But they wouldn't do that, or manage to justify it, if the risks from the disease weren't massive
Thirteenth, health ministers like the German one are now openly speaking up about the dangers of covid. We know policymakers aren't prone to raise the alarm on #LongCovid for many reasons (economy etc.). If some are willing to do it, we're on the brink of very severe effects

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More from @elisaperego78

Sep 22
"Low-field MRI showed persistent pulmonary dysfunction in both children and adolescents recovered from covid and with long covid."
I tweeted this 2.000 times. #LongCovid can be "silent", subclinical 🧵

"Pulmonary dysfunction after pediatric covid" pubs.rsna.org/doi/10.1148/ra…
Many of those who report minimal symptoms or are apparently "asymptomatic" in the acute and long phase of covid, might still have severe underlying, "silent" pathology. Symptoms | perception and reporting by the patient | don't always match deep-down pathology.
Many diseases, especially in their early phases, can be asymptomatic or pauci-symptomatic, including cancers, like colon cancer. This is why we have screening in place! To pick up underlying, "silent" pathology.
Read 10 tweets
Sep 22
The extent of long-term covid sequelae emerging from the analysis of health records is huge.
Now, let's think many never had access to a covid test, to proper care, diagnosis, and testing. Their Long Covid is nowhere to be seen. The ramifications of this pandemic are monstrous.
Did we know this was going to happen in 2020? Yes, because those of us in the early red zones were seeing it, and reporting, including in scientific papers. Policymakers and health bodies have minimized this critical evidence and allowed a SARS virus to rip through the population
Many studies on covid sequelae require a positive SARS-CoV-2 test to include a patient. Many people, especially in the early hotspots, were denied testing. Tests were often available only to those who had been in China! even when SARS-CoV-2 was already spreading everywhere
Read 9 tweets
Sep 21
[death, covid]

A thread on musicians and associates who died or suffered from severe covid—#LongCovid 2020—2022. I came across many stories by chance in an unrelated search. Artists are "rare" people. High numbers there means covid's havoc isn't rare

🧵
Musicians and other performing artists are also among, potentially, the most exposed categories: they might have to interact with many people, travel, and perform live. Not everyone, however, was exposed through work. Thread underlines the need for safe spaces and ventilation
Joseph Kamal Rodrigues, 68, one of Bangladesh's most celebrated singers, died from covid in February 2021. He allegedly suffered from kidney disease, which may have aggravated his covid

asianews.it/notizie-it/Mor…
Read 69 tweets
Sep 21
"The alarm bells are going off"
German football stars Manuel Neuer and Leon Goretzka tested positive for covid. They will miss the upcoming Nations League games.
The two attended the Oktoberfest a few days ago.
Winter is coming.
Early, actually.

apnews.com/article/soccer…
As usual, even if the two don't develop #LongCovid or suffer from other severe outcomes, adding a new, dangerous, fast-evolving pathogen to our world, is going to be highly disruptive for every day life.
Another player in the squad, Julian Brandt, has also left the Germany team, with flu-like symptoms, though he has tested negative for the coronavirus.

eurosport.co.uk/football/manue…
Read 6 tweets
Sep 21
We have some answers to this question i.e. who is dying from covid in these last few waves. Children. Elderly people. Middle age people. Quite a few who were vaccinated. A famous Spanish writer. Human beings.

🧵
Spanish author Javier Marias died from covid-pneumonia complications in September 2022, after being hospitalized for months. Javier was considered one of the great of contemporary Spanish literature

#LongCovid

scmp.com/news/world/eur…
A 10 year-old child died from covid at the Bambino Gesù hospital in Rome in February 2022. He had been hospitalized in critical care since 31 January.

adnkronos.com/covid-italia-b…
Read 24 tweets
Sep 20
More evidence of cardiovascular events in covid and #LongCovid

Incidence of vascular events like arterial thromboses and VTEs remains elevated up to 49 weeks after a covid diagnosis

A huge analysis of clinical records from 2020 in England and Wales

ahajournals.org/doi/10.1161/CI…
"High relative incidence of vascular events soon after COVID-19 diagnosis declines more rapidly for arterial thromboses than VTEs. However, incidence remains elevated up to 49 weeks after COVID-19 diagnosis. "
"These results support policies to prevent severe covid by means of covid vaccines, early review after discharge, risk factor control, and use of secondary preventive agents in high-risk patients."

#LongCovid
Read 4 tweets

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