@ESICMpubmed.ncbi.nlm.nih.gov/27626706/ Successful weaning (or successful separation) - extubation without death or reintubation within next 7 days. same for tracheostomy.
Different groups and trajectories
ABCDE of weaning 1. airway and lung (compliance, resistance and gas exchange) 2. Brain (delirium, cognitive dysfunction) 3. Cardiac (Echo, after load reduction ) 4. Diaphragm (Pi max, early mobilisation) 5. Endocrine.(adequate energy intake ) pubmed.ncbi.nlm.nih.gov/21143773/
Very comprehensive. Essentially excellent holistic icu care
Q: How to perform SBT?
a). low PS and PEEP
b). low PS without PEEP
c). using cPAP(i.e., PEEP)
d). T-piece with o2 supply
What would you do ?
pressure support can mask cardiac failure due to PS reducing LV after load.
Potentially gastric pressure monitoring can also give additional information. Eadi - measure electrical activity of the diaphragm - more commonly known as "NAVA"
NAVA levels set accordingly - e.g., 2cmH20 per micro volt. What is the effect of PS on EA di ? atsjournals.org/doi/pdf/10.116…
Mariangela PELLEGRINI
Uppsala- Sweden
"Do we Need a biological definition of ARDS"
- Berlin definition has NO Diffuse alveolar damage .
- the Berlin defn does not capture well
Frohlich - different definitions specificity of 0.63, 0.42, 0.31 even! #ventilation#ards#LIVES2022
ARDS - new definition or phenotypes by @GicoBellani refreshing with Kigali definition of ARDS - useful not just low resource but during pandemic in supposedly high income settings and only draw back is no PEEp requirement #ards#ventilation#LIVES2022@ESICM
@GicoBellani@ESICM Resolved versus confirmed ARDS
- prospectively applying Berlin definition did work but if ya wait 24 hrs and re-measure P/F ratio, you end up stratifying much better.
- Better separation of groups
NEXT Speaker : VA ecmo for which patients?
Alain COMBES
Severe cardiogenic shock has different phenotypes 1. medical cardiogenic shock(AMI, end stage dilated CM, myocarditis, septic shock) 2. Post cardiotomy refractory CS (post CABG) #LIVES2022 @ESICM#ecmo#resuscitation#ALS
@ESICM 2022 what do the guidelines say
- ESC recommends short term MCS should be considred in cardiogenic shock.
IABP may be considered but not routinely recommended in post MI #LIVES2022
@ESICM PARAMEDIC 2 - big study
8007 pts, adrenaline 4000, placebo 3999
- a lot of discussion post trial
- need a nuanced interpretation.
- 19 "more good" survivors and 5 "more bad" survivors in adrenaline arm.